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191.
Bertrand Schweitzer-Chaput Massaba Keita Thierry Milcent Sandrine Ongeri Benoit Crousse 《Tetrahedron》2012,68(35):7028-7034
A series of fluorinated N-aminoaziridines have been synthesized by the PhI(OAc)2-mediated aziridination procedure. The reaction was carried out with various protected hydrazides and fluorinated alkenes. The reaction was extended to alkenes bearing an amino acid and the ring opening of the CF3–N-aminoaziridines has been investigated. 相似文献
192.
Nadge Brun Itab Youssef Marie‐Claire Chevrel David Chapron Cornlius Schrauwen Sandrine Hoppe Patrice Bourson Alain Durand 《Journal of Raman spectroscopy : JRS》2013,44(6):909-915
Free radical polymerization of styrene was monitored in situ by combining Raman spectroscopy to other experimental techniques (gravimetry and rheology). Three different processes were investigated: bulk, emulsion and miniemulsion polymerization. A complete analysis of the evolution of Raman spectrum during the course of reaction showed that a lot of information about molecular dynamics could be extracted and related to chemical phenomena. In addition, we report for the first time the coupling of Raman spectroscopy to a rheometer in order to monitor styrene bulk polymerization both at the scale of chemical bonds and at the scale of macroscopic phenomena (viscosity variation). Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
193.
AC Cruickshank CJ Dotzler S Din S Heutz MF Toney MP Ryan 《Journal of the American Chemical Society》2012,134(35):14302-14305
The structure of copper phthalocyanine (CuPc) thin films (5-100 nm) deposited on single-crystal ZnO(11?00) substrates by organic molecular beam deposition was determined from grazing-incidence X-ray diffraction reciprocal space maps. The crystal structure was identified as the metastable polymorph α-CuPc, but the molecular stacking was found to vary depending on the film thickness: for thin films, a herringbone arrangement was observed, whereas for films thicker than 10 nm, coexistence of both the herringbone and brickstone arrangements was found. We propose a modified structure for the herringbone phase with a larger monoclinic β angle, which leads to intrastack Cu-Cu distances closer to those in the brickstone phase. This structural basis enables an understanding of the functional properties (e.g., light absorption and charge transport) of (opto)electronic devices fabricated from CuPc/ZnO hybrid systems. 相似文献
194.
This contribution focuses on two different developments of mechanical-computational methods for the optimal determination of the initial shape of formed functional components knowing the deformed configuration, the applied loads and the boundary conditions. The first method uses an inverse mechanical formulation and can be applied to materials with hyperelastic behaviors. For materials with elastoplastic properties this method is not advocated, without knowing the final plastic strains, due to the non uniqueness of the solution. The second method uses a shape optimization formulation in the sense of an inverse problem via successive iterations of the direct problem. For hyperelastic materials the inverse mechanical formulation is preferred for its velocity and the non exhibition of possible mesh distortions. In the shape optimization formulation mesh distortions can be avoided by an update of the reference configuration of the functional part. Both methods are using a formulation in the logarithmic strain space. A numerical example for materials with isotropic elastoplastic behaviors illustrates the shape optimization formulation. (© 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim) 相似文献
195.
Magali Deleu Sylvain Gatard Emeline Payen Laurence Lins Katherine Nott Christelle Flore Romain Thomas Michel Paquot Sandrine Bouquillon 《Comptes Rendus Chimie》2012,15(1):68-74
A two-step synthesis, with good yields, of d-xylose-based bolaamphiphiles is described. The monolayer properties, the adsorption behavior and membrane destabilization properties of two bolaamphiphiles differing by their spacers (presence or absence of one double bond) were studied. The presence of one unsaturation has no influence on the interfacial organization at low compression but impairs the stability of the monolayer at high compression. Saturated and unsaturated molecules are suggested to adopt a loop structure at the interface at low compression. The higher degree of freedom of the saturated hydrophobic spacer does not affect the initial diffusion step of the bolaform from the subphase to the interface but greatly slows the arrangement step at the interface. However, once at the interface, their surface-active properties are similar. The higher flexibility of the saturated analogue spacer also greatly increases its lipid vesicle destabilizing property. Its rearrangement within the lipid bilayer is in favour of the formation of inverted phases, facilitating membrane fusion. 相似文献
196.
Following the study of the alkoxypyrazoles nitrogen's reactivity toward arylation or alkylation reactions, we report here our results on the introduction of various aryl groups on carbon 4 position of 3-alkoxypyrazoles. This was achieved from the corresponding 4-halogeno derivatives via a Suzuki-Miyaura aryl-aryl coupling reaction. The unexpected difficulties (lack of reactivity or unwanted halogen reduction) encountered in the C-4 arylation of NH-free 4-halogenopyrazoles led us to design solutions to this recurrent problem. The cleavage of the 3-alkoxy group was also investigated using hydrogen bromide in acetic acid or boron tribromide in dichloromethane. This led, in one case, to the observation of a remarkable neighboring group-assisted electrophilic aryl boronylation. This second part of our work paves the way to the synthesis of many original chemical libraries featuring 3-alkoxy 1,4-diaryl pyrazoles as well as the corresponding 1,4-diaryl pyrazol-3-ones. 相似文献
197.
Fabrice Guittonneau Abdesselam Abdelouas Bernd Grambow Sandrine Huclier 《Ultrasonics sonochemistry》2010,17(2):391-398
Ultrasound treatment was used to study the decrease of the granulometry of graphite, due to the cavitation, which allows the erosion by separating grains. At a smaller scale, cavitation bubble implosion tears apart graphite sheets as shown by HRTEM, while HO and H radicals produced from water sonolysis, generate oxidative and reductive reactions on these sheet fragments. Such reactions form smaller species, e.g. dissolved organic matter. The methodology proposed is very sensitive to unambiguously identifying the in situ composition of organic compounds in water. The use of the atmospheric pressure chemical ionization (APCI) Fourier transform mass spectrometry (FTMS) technique minimizes the perturbation of the organic composition and does not require chemical treatment for analysis. The structural features observed in the narrow range (m/z < 300) were mainly aromatic compounds (phenol, benzene, toluene, xylene, benzenediazonium, etc.), C4–C6 alkenes and C2–C10 carboxylic acids. Synthesis of small compounds from graphite sonication has never been reported and will probably be helpful to understand the mechanisms involved in high energy radical reactions. 相似文献
198.
Sandrine Chalaye Elodie Bourgeat‐Lami Jean‐Luc Putaux Jacques Lang 《Macromolecular Symposia》2001,169(1):89-96
Encapsulation of silica nanoparticles was performed by dispersion polymerization of styrene, butyl acrylate and butyl methacrylate in aqueous alcoholic media. Following previous works1‐3), the silica beads were first modified by reacting on their surface the 3‐trimethoxysilyl propyl methacrylate coupling agent (MPS). In every case, the silica beads are all surrounded by polymer giving composite latex particles filled with silica. Each composite particle contains from one to a great number of silica beads. Changing the size or the concentration of the silica beads, and the experimental conditions for the synthesis of the polymer particles enables to control this number. One can take benefit of this to synthesize model composite particles with controlled compositions. 相似文献
199.
Estelle Rascol Sandrine Villette Etienne Hart Isabel D. Alves 《Molecules (Basel, Switzerland)》2021,26(21)
Plasmon waveguide resonance (PWR) is a variant of surface plasmon resonance (SPR) that was invented about two decades ago at the University of Arizona. In addition to the characterization of the kinetics and affinity of molecular interactions, PWR possesses several advantages relative to SPR, namely, the ability to monitor both mass and structural changes. PWR allows anisotropy information to be obtained and is ideal for the investigation of molecular interactions occurring in anisotropic-oriented thin films. In this review, we will revisit main PWR applications, aiming at characterizing molecular interactions occurring (1) at lipid membranes deposited in the sensor and (2) in chemically modified sensors. Among the most widely used applications is the investigation of G-protein coupled receptor (GPCR) ligand activation and the study of the lipid environment’s impact on this process. Pioneering PWR studies on GPCRs were carried out thanks to the strong and effective collaboration between two laboratories in the University of Arizona leaded by Dr. Gordon Tollin and Dr. Victor J. Hruby. This review provides an overview of the main applications of PWR and provides a historical perspective on the development of instruments since the first prototype and continuous technological improvements to ongoing and future developments, aiming at broadening the information obtained and expanding the application portfolio. 相似文献
200.