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Biodegradable Cell-Seeded Collagen Based Polymer Scaffolds for Wound Healing and Skin Reconstruction
Mojtaba Ansari Soheila Salahshoor Kordestani Sanaz Nazralizadeh Hossein Eslami 《Journal of Macromolecular Science: Physics》2018,57(2):100-109
In the present study a collagen-glycosaminoglycans scaffold, following chemical modifications, was prepared as an analog of the extracellular matrix (ECM) by a freeze drying method. Appropriate tests related to its use for wound healing (evaluation of the structure by scanning electron microscopy, swelling properties, biodegradability properties, Fourier transform infrared spectroscopy and cell culture) were done on the scaffolds. Amniotic fluid-derived stem (AFS) cell seeded scaffolds were shown to be potentially useful for wound healing. 相似文献