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11.
A set of 11 non-symmetric cyclic sulfamide HIV-1 protease inhibitors were synthesized and evaluated. The use of a key microwave-assisted silver(I) oxide mediated selective mono N-benzylation reaction enabled fast and straightforward synthesis. The Ki values of the new inhibitors ranged between 0.28 μM and >20 μM. 相似文献
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Bijoy Kundu Hsiang-nan Li Jim Samuelsson Pankaj Jain 《The European Physical Journal C - Particles and Fields》1999,8(4):637-642
We recalculate the proton Dirac form factor based on the perturbative QCD factorization theorem, which includes Sudakov suppression.
The evolution scale of the proton wave functions and the infrared cutoffs for the Sudakov re-summation are carefully chosen
such that the soft divergences from large coupling constants are diminished and perturbative QCD predictions are stabilized.
We find that the King–Sachrajda model for the proton wave function leads to results which are in better agreement with experimental
data than those from the Chernyak–Zhitnitsky wave function.
Received: 27 November 1998 / Published online: 7 April 1999 相似文献
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Mats Andersson H⇘kan Samuelsson Sebastian Sandberg 《Journal d'Analyse Mathématique》2006,98(1):221-247
We introduce a class of (tuples of commuting) unbounded operators on a Banach space, admitting smooth functional calculi, which contains all operators of Helffer-Sjöstrand type and is closed under the action of smooth proper mappings. Moreover, the class is closed under tensor product of commuting operators. In general, and operator in this class has no resolvent in the usual sense, so the spectrum must be defined in terms of the functional calculus. We also consider invariant subspaces and spectral decompositions. 相似文献
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Shitov AV Zharmukhamedov SK Shutova TV Allakhverdiev SI Samuelsson G Klimov VV 《Journal of photochemistry and photobiology. B, Biology》2011,104(1-2):366-371
The effects of suppression of the carbonic anhydrase (CA) activity by a CA-inhibitor, acetazolamide (AA), on the photosynthetic activities of photosystem II (PS II) particles from higher plants were investigated. AA along with CA-activity inhibits the PS II photosynthetic electron transfer and the AA-induced suppression is totally reversed by the addition of bicarbonate (3-5 mM). Similar effect of recovery in the PS II photosynthetic activity was also revealed upon the addition of known artificial electron donors (potassium ferrocyanide and TMPD). Significance and possible functions of CA for the PS II donor side are discussed. 相似文献
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J. M. Curtis P. J. Derrick J. Holgersson B. E. Samuelsson M. E. Breimer 《Journal of the American Society for Mass Spectrometry》1992,3(4):353-359
A permethylated-reduced hexaglycosylceramide in a complex glycolipid mixture isolated from a unique human tissue has been identified by using tandem mass spectrometry (MS/MS). The mass spectrum of this glycolipid mixture, obtained by using in-beam electron ionization, is very complex, and fragment ions derived from the hexaglycosylceramide cannot be distinguished from other ions. Tandem mass spectrometry using a four-sector mass spectrometer gave the mass spectrum of the immonium ion of the permethylated-reduced hexaglycosykeramide (m / z 1645.8), which is characteristic of its structure. Comparison of this MS/MS spectrum with those of two similarly derivatized blood group hexaglycosylceramide isomers permitted identification of the unknown glycolipid structure. 相似文献
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