Astrophysical S-factors from asymptotic normalization coefficients

S-factors for direct capture reactions can be found at astrophysical energies from asymptotic normalization coefficients which provide the normalization of the tail of the overlap function. For example the overlap for ⁸B → ⁷Be+p defines the S-factor for ⁷Be (p, γ)⁸B. Peripheral transfer reactions offer a technique to determine these asymptotic normalization coefficients. As a test of the technique, the ¹⁶O(³He, d)¹⁷F reaction has been used to determine asymptotic normalization coefficients for transitions to the ground and first excited states of ¹⁷F. The S-factors for ¹⁶O(p, γ)¹⁷F calculated from these ¹⁷F → ¹⁶O+p asymptotic normalization coefficients are found to be in very good agreement with recent measurements. Following the same technique, the ¹⁰B(⁷Be, ⁸B)⁹Be and ¹⁴N(⁷Be, ⁸B)¹³C reactions have been used to measure the asymptotic normalization coefficient for ⁷Be(p, γ)⁸B. This result provides an indirect determination of S ₁₇(0).     

Line intensities for the ν1, ν3 and ν1+ν3 bands of 34SO2

Using both high resolution (0.0018 cm^?1) and medium resolution (0.112 cm^?1) Fourier transform spectra of an enriched ³⁴S (95.3%) sample of sulfur dioxide, it has been possible to accurately measure a large number of individual line intensities for some of the strongest of the SO₂ bands, i.e. ν₁, ν₃ and ν₁₊ν₃. These intensities were least-squares fitted using a theoretical model which takes into account the vibration–rotation interactions linking the upper energy levels where needed, and, in this way, expansions of the various transition moment operators were determined. The Hamiltonian parameters determined in previous analyses together with these moments were then used to generate synthetic spectra for the bands studied and their corresponding hot bands providing one with an extensive picture of the absorption spectrum of ³⁴SO₂ in the spectral domains, 8.7, 7.4, and 4 μm.     

Atmospheric pressure desorption/ionization on silicon ion trap mass spectrometry applied to the quantitation of midazolam in rat plasma and determination of midazolam 1'-hydroxylation kinetics in human liver microsomes

The application of atmospheric pressure desorption/ionization on silicon (AP-DIOS) coupled with ion trap mass spectrometry (ITMS) was investigated for the quantification of midazolam in rat plasma, and determination of midazolam 1'-hydroxylation kinetics in pooled human liver microsomes. Results indicate good sensitivity with absolute detection limits for midazolam in rat plasma of approximately 300 femtograms. A linear dynamic range from approximately 10-5000 ng/mL was obtained in rat plasma with analysis times of 1 min per sample. Kinetic constants for midazolam 1'-hydroxylation in human liver microsomes yielded an apparent Km of 10.0 microM and Vmax of 6.4 nmol/min/mg. Studies investigating the inhibition of 1'-hydroxymidazolam formation by the cytochrome P450 3A4 model inhibitor ketoconazole yielded an IC50 of 0.03 microM. Quantitative precision for replicate analysis of rat plasma and human liver microsomal samples was variable with relative standard deviation (RSD) values ranging from a low of approximately 3% to over 50%, with the highest variability observed in data from human liver microsomal incubations. While preliminary studies investigating the application of AP-DIOS-ITMS suggested feasibility of this technique to typical pharmacokinetic applications, further work is required to understand the underlying causes for the high variability observed in these investigations.     

Injection of atoms and molecules in a superfluid helium fountain: Cu and Cu2He(n) (n = 1, ..., ∞)

We introduce an experimental platform designed around a thermomechanical helium fountain, which is aimed at investigating spectroscopy and dynamics of atoms and molecules in the superfluid and at its vapor interface. Laser ablation of copper, efficient cooling and transport of Cu and Cu(2) through helium vapor (1.5 K < T < 20 K), formation of linear and T-shaped Cu(2)-He complexes, and their continuous evolution into large Cu(2)-He(n) clusters and droplets are among the processes that are illustrated. Reflection is the dominant quantum scattering channel of translationally cold copper atoms (T = 1.7 K) at the fountain interface. Cu(2) dimers mainly travel through the fountain unimpeded. However, the conditions of fountain flow and transport of molecules can be controlled to demonstrate injection and, in particular, injection into a nondivergent columnar fountain with a plug velocity of about 1 m/s. The experimental observables are interpreted with the aid of bosonic density functional theory calculations and ab initio interaction potentials.     

The effect of topical anesthesia on vocal fold motion

The objective of this study was to determine if topical anesthesia to the larynx and pharynx affects vocal fold motion during dynamic voice evaluation with transnasal flexible endoscopy. Transnasal dynamic laryngeal examinations of 10 patients with no voice complaints were evaluated by five blinded fellowship-trained laryngologists. Each patient was examined before and after application of topical anesthetic. Reviewers rated briskness of right and left vocal fold movement and longitudinal tension on a visual analogue scale. Statistical comparisons were made between individual subject scores before and after anesthetic application. Inter-rater reliability was also assessed. No statistical difference was observed between subject scores before and after anesthetic application. Average intraclass correlation coefficients were 0.643 and 0.591 for pre- and postanesthesia scores, respectively. Application of topical anesthesia to the larynx and pharynx does not affect vocal fold motion.     

等离子体边界层扩散时间演化的稳定性与突变 *

解析分析了外界控制下等离子体边界层扩散过程时间演化的稳定性与突变条件,并将这些条件应用于JFT-2M Tokamak,结果表明,一阶共振下粒子注入或(和)外加电场的无量纲幅值(ε₁或(和)ε₂)满足一定条件时系统处于稳定状态;二阶共振下当ε₁或(和)ε₂等于某值时系统会发生突变,从低约束态跃迁至高约束态.     

Determining a 'safe' high-mass limit in matrix-assisted laser desorption/ionisation time-of-flight mass spectra of coal derived materials with reference to instrument noise

Three methods for determining a 'safe' estimate for high-mass limits of MALDI spectra of coal derived liquids were explored, using a sample of coal-tar pitch and its pyridine-insoluble fraction. Co-addition of increasing numbers of single-shot spectra (10, 30, 50 and 100 pulses) showed visually observable reductions in noise levels, consistent with robust and statistically meaningful signals. Three separate types of post-acquisition calculation were used to identify high-mass limits of the spectra. (i) A literature method indicated high-mass limits similar to those observed visually-as a shift from baseline at the highest masses, nearly 350 000 u for the coal tar pitch and about 390 000 u for its pyridine insoluble fraction. (ii) Comparing instrument signal with pre-selected multiples of the standard deviation, upper mass estimates of between 40-60 000 u for the coal-tar pitch and about 95 000 u for its pyridine-insoluble fraction were found. (iii) Calculation of the slope was used to identify 'lift-off' of the spectrum from baseline. The angle between the smoothed spectrum and the baseline was matched to a pre-selected value (e.g. 0.5 degrees and 1 degrees ). However, the arbitrary specification of the key parameter did not establish this last method on a firm basis. The choice of a criterion for estimating high-mass limits of MALDI spectra remains a semi-quantitative procedure; a reasonably conservative high-mass limit may be estimated by comparison of signal with five times the standard deviation. However, evaluation of size exclusion chromatograms of the present samples using polystyrene standards suggests that molecular mass distributions of pitch samples arrived at by MALDI mass spectrometry are, at least partly, determined by the limitations of available instruments. Copyright 1999 John Wiley & Sons, Ltd.     

用于边缘检测的Laplace——样条(▽2S)算子

根据数据平滑理论,提出了一种图象边缘检测的方法:把二维四阶B样条函数与Laplacian算子相结合组合成▽²S算子,对图象卷积之后,根据过零点(ZeroCrossing)确定图象边缘。文中证明了它在图象平滑和边缘检测效果上,优于Marr和Hildreth提出的▽²G算子,且计算量较小。而▽²G算子可用高阶▽²S算子近似。文中给出了一些实验结果。     

非线性回旋动力方程

非线性回旋动力方程是处理等离子体中非线性电磁现象及相关输运现象的有力工具.在任意磁场位形、任意频率下,建立了一套适于描述非线性电磁现象、保留有限Larmor半径(FLR)效应的、自洽的非线性回旋动力的Vlasov-Maxwell方程.     

叶绿体结构和功能的研究——叶绿体残缺膜与线粒体嵴膜组合光合磷酸化活力的重建

本文证明了类囊体残缺膜可以与线粒体嵴膜组合而成为新囊膜。这种膜组织可以通过嵴膜的偶联因子借光能来进行光合磷酸化。电子显微镜图谱显示,这种膜组织是介乎残缺膜与嵴膜之间一种膜组织。 试验结果支持了这样一种观点,即:叶绿体内光合磷酸化与线粒体内氧化磷酸化的磷酸化机构是一致的,其细胞器可能是有着共同的来源。