全文获取类型
收费全文 | 249篇 |
免费 | 12篇 |
国内免费 | 3篇 |
专业分类
化学 | 207篇 |
晶体学 | 5篇 |
力学 | 4篇 |
数学 | 12篇 |
物理学 | 36篇 |
出版年
2024年 | 2篇 |
2023年 | 8篇 |
2022年 | 23篇 |
2021年 | 21篇 |
2020年 | 16篇 |
2019年 | 17篇 |
2018年 | 23篇 |
2017年 | 20篇 |
2016年 | 17篇 |
2015年 | 10篇 |
2014年 | 10篇 |
2013年 | 25篇 |
2012年 | 10篇 |
2011年 | 11篇 |
2010年 | 7篇 |
2009年 | 6篇 |
2008年 | 7篇 |
2007年 | 4篇 |
2006年 | 3篇 |
2005年 | 2篇 |
2004年 | 3篇 |
2003年 | 1篇 |
2002年 | 3篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1999年 | 3篇 |
1998年 | 3篇 |
1996年 | 2篇 |
1995年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1973年 | 1篇 |
排序方式: 共有264条查询结果,搜索用时 15 毫秒
211.
Sahar Baniyaghoob Mohammad Mahdi Najafpour Davar M. Boghaei 《Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy》2010,75(3):970-977
Charge-transfer (CT) complexes formed from the reactions of 4-nitropyrocatechol (4-nCat) as an electron acceptor with four amino alcohols: 2-aminoethanol, 1-amino-2-propanol, 4-aminobutanol and N-(2-hydroxyethyl)-1,3-diaminopropane (NHEDAP) as electron donors, have been studied spectrophotometrically in H2O and H2O/EtOH at 20, 25, 30, 35 and 40 °C. The calculated values of the oscillator strength and transition moment confirm the formation of CT-complexes. The thermodynamic and spectroscopic parameters were also evaluated for the formation of CT-complexes. The equilibrium constants ranged from 9.00 to 2.20 l mol?1 (M?1). These interactions are exothermic and have relatively large standard enthalpy and entropy changes (ΔH values ranged from ?15.58 to ?3.10 kJ mol?1; ΔS ranged from 26.81 to ?3.25 J K?1 mol?1). The solid CT-complexes have been synthesized and characterized by IR, NMR, mass spectrometry and thermal analysis. The photometric titration curves and other spectrometric data for the reactions indicated that the data obtained refer to the formation of 1:1 charge-transfer complex of [(4-nCat) (NHEDAP)] and 1:2 charge-transfer complexes of other amino alcohols [(4-nCat) (amino alcohol)2]. The effect of alkali and alkaline earth metals on increasing the equilibrium constant of the CT-complexation was also investigated. 相似文献
212.
Molecular Diversity - Possible application of incorporating a well-known drug (benzocaine) with cyanoacetamide function to get a powerful synthon ethyl 4-cyanoacetamido benzoate. This synthetic... 相似文献
213.
Bagher Eftekhari-Sis Sahar Mohajer Maryam Zirak Gholam Reza Mahdavinia Orhan Büyükgüngör 《Journal of the Iranian Chemical Society》2016,13(4):609-615
A new polymeric laponite nanoclay heterogeneous catalytic system based on HPMC (hydroxypropyl methyl cellulose) was developed for direct Mannich-type reaction of ketones with substituted benzaldehydes and anilines to afford corresponding β-amino ketones in good to high yields. Interestingly, cyclic ketones exhibited different chemoselectivity. Cyclopentanone underwent aldol condensation to give crossed-aldol product, while cyclohexanone and cyclopentanone afforded corresponding Mannich adducts. In the case of cyclohexanone, stereoselectivity was changed depending on the nature of the substitution on benzaldehydes, in which, moderate electron-donating and electron-withdrawing groups afforded the anti isomer as major products, but strongly electron-donating substituted benzaldehydes led to syn isomer as the major Mannich adducts. Mannich reaction with cycloheptanone led to Mannich adducts with excellent syn selectivity. 相似文献
214.
Novel composite membranes embedded with molecularly imprinted porous polymeric nanospheres for targeted phenol 下载免费PDF全文
In the present research, novel hybrid molecularly imprinted polymer (HMIP) membranes were synthesized for selective adsorption and separation of phenol toxic molecules from aqueous solutions. Molecularly imprinted polymer (MIP) nanospheres for targeted phenol were successfully prepared using precipitation polymerization of methacrylic acid, trimethylolpropane trimethacrylate, and ethylene glycol dimethacrylate, followed by integrating into polysulfone matrix to create the HMIP membranes via a phase inversion method. The fabricated materials were characterized from the viewpoints of spectroscopic analysis, structural and surface morphological properties, porosimetry, and batch rebinding assays. The imprinted polymeric nanospheres with mean diameter value ranging from 210 to 250 nm and average pore diameter of 8 nm were obtained according to the morphological and Brunauer–Emmett–Teller analysis, respectively. Scanning electron microscopy pictures demonstrated that the MIP spheres were uniformly distributed on the surface and in the bulk polymer phase of the hybrid membrane. The surface roughness, porosity, and permeate flux of membrane were significantly augmented by addition of the imprinted polymer particles in the dope solution. HMIP‐2 membrane containing 10 wt% of MIP showed the highest binding capacity and an excellent molecular recognition for phenol with respect to the correlative blank membrane. The selective recognition of phenol on the HMIP‐2 membrane was 3.5 times larger than the analogous compound (i.e. catechol). Moreover, the maximum separation factor of phenol was obtained as 2.19 relative to catechol through selective permeation studies, which was also observed for HMIP‐2 membrane. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
215.
Understanding the composition of complex hydrocarbon mixtures is important for environmental studies in diverse fields, but many prevalent compounds cannot be confidently identified using traditional gas chromatography (GC) techniques. Increasing requirements on analyses of isomeric compounds and the problems encountered in their separation demand a study of more efficient systems which exhibit a high selectivity. Kelker and Fresenius first used nematic liquid crystals as stereospecific stationary phases in GC. Nematic liquid crystal has shown this particular selectivity and sensitivity as stationary phases for the separation of isomers having similar volatilities. Because of their unique selectivity towards rigid solute isomers, liquid crystal stationary phases were considered at one time to be a very promising class of materials that give gas chromatographic separations very different from those that can be obtained with any other stationary phase. Since then, a great deal of attention has been paid to the separation properties of this relatively wide group of substances. Liquid crystal can be used to separate a variety of compounds including isomer mixtures which cannot be separated on conventional stationary phases. This paper aims to review all specific experimental results and presents a comparative analytical study of monomeric nematic liquid crystal stationary phases used in GC. A further contribution of this review is in the field of isomeric compounds separation. 相似文献
216.
Abdollah Ardebili Mohammad Hassan Pouriayevali Sahar Aleshikh Marziyeh Zahani Mehdi Ajorloo Ahdieh Izanloo Abolghasem Siyadatpanah Hadi Razavi Nikoo Polrat Wilairatana Henrique Douglas Melo Coutinho 《Molecules (Basel, Switzerland)》2021,26(22)
The treatment of viral disease has become a medical challenge because of the increasing incidence and prevalence of human viral pathogens, as well as the lack of viable treatment alternatives, including plant-derived strategies. This review attempts to investigate the trends of research on in vitro antiviral effects of curcumin against different classes of human viral pathogens worldwide. Various electronic databases, including PubMed, Scopus, Web of Science, and Google Scholar were searched for published English articles evaluating the anti-viral activity of curcumin. Data were then extracted and analyzed. The forty-three studies (published from 1993 to 2020) that were identified contain data for 24 different viruses. The 50% cytotoxic concentration (CC50), 50% effective/inhibitory concentration (EC50/IC50), and stimulation index (SI) parameters showed that curcumin had antiviral activity against viruses causing diseases in humans. Data presented in this review highlight the potential antiviral applications of curcumin and open new avenues for further experiments on the clinical applications of curcumin and its derivatives. 相似文献
217.
Issam M. Gabr Hala A. El-Asmy Mohamed S. Emmam Sahar I. Mostafa 《Transition Metal Chemistry》2009,34(4):409-418
Synthetic procedures are described that allow access to the new complexes cis-[Mo2O5(apc)2], cis-[WO2(apc)2], trans-[UO2(apc)2], [Ru(apc)2(H2O)2], [Ru(PPh3)2(apc)2], [Rh(apc)3], [Rh(PPh3)2(apc)2]ClO4, [M(apc)2], [M(PPh3)2(apc)]Cl, [M(bpy)(apc)]Cl (M(II) = Pd, Pt), [Pd(bpy)(apc)Cl], [Ag(apc)(H2O)2] and [Ir(bpy)(Hapc)2]Cl3, where Hapc, is 3-aminopyrazine-2-carboxylic acid. These complexes were characterized by physico-chemical and spectroscopic
techniques. Both Hapc and several of its complexes display significant anticancer activity against Ehrlich ascites tumour cells (EAC) in albino mice. 相似文献
218.
Yasin Fadaei Ali Ahmadi Kiavash Fekri Rohollah Masoumi Ami Radunskaya 《Mathematical Methods in the Applied Sciences》2021,44(1):391-406
In this study, a mathematical, fractional‐order model was developed for B cell chronic lymphocytic leukemia, with immune system, and then analyzed. Interactions between B leukemia cells, natural killer cells, cytotoxic T cells, and T‐helper cells are considered to be incorporated into a system consisting of four fractional differential equations. For estimation of the parameters, clinical data of six patients were used. By numerical solution of the system, the interactions between the leukemia cell population and the immune system cell populations for values of α ∈ (0,1) at different times were explained. By determining points of equilibrium and stability of the system were met. Bifurcation analysis showed that use of the fractional‐order model, figure out unpredictable behaviors of the system such as saddle‐node, bistability and hysteresis phenomenon occurred in the system by changing the values of some of the parameters, it was predictable. 相似文献
219.
Molecular structure, conformational stability and vibrational wave numbers for the rotational isomers of 2-furoyl chloride and 3-furoyl chloride have been computed using the B3LYP method with the 6-311++G(d,p) basis set. From computations, 2-furoyl chloride was predicated to exist predominantly in cis conformation with cis–trans rotational barrier 40.40 kJ·mol?1, and 3-furoyl chloride was predicated to exist predominantly in the trans conformation with cis–trans rotational barrier 30.17 kJ·mol?1. The effects of solvents on the conformational stability of all the molecules in nine different solvents (heptane, chloroform, tetrahydrofuran, dichloroethane, acetone, ethanol, methanol, dimethylsulfoxide and water) were investigated. The integral equation formalism of the polarizable continuum model was used for all solution phase computations. The vibrational wave numbers and the corresponding vibrational assignments of the molecules in C1 symmetry were examined and the simulated infrared spectra of the molecules are reported. The geometrical parameters, highest occupied and lowest unoccupied molecular orbitals, Infrared intensities, and molecular electrostatic potentials results are reported. 相似文献
220.
Several novel 6-aryl-5-cyano thiouracil derivatives were synthesized and explored for their activities as antibacterial, antifungal and anticancer agents. The antimicrobial evaluation revealed that compounds 7b and 7c possessed superior antibacterial activity against the Gram positive bacteria S. aureus and B. subtilis compared to the reference drug amoxicillin. Moreover, compound 4i was found to be a broad spectrum antimicrobial agent and it also exhibited the highest antifungal activity against C. albicans, even higher than the reference drug amphotericin B (MIC = 2.34, 3.00 μg/mL respectively). Selected compounds were tested for in vitro cytotoxicity at a single 10-5 M concentration in accordance to the NCI (USA) protocol. The preliminary screening results showed that most of the compounds had limited cytotoxic activity against renal cancer UO-31 and/or A498 cell lines. Nevertheless, compounds 6d and 6i displayed potent growth inhibitory effect toward non-small cell lung cancer HOP-92 and leukemia MOLT-4 cell lines, respectively. 相似文献