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421.
Polymer supported reagents have found many applications in recent years. Scientists in research laboratories of agrochemical and pharmaceutical industries now routinely utilize these compounds to prepare ensembles of small organic molecules for screening. This review is aimed to highlight some of the most important applications of these promising materials in organic synthesis. Furthermore, an extensive listing of polymeric reagents that were recently used in organic synthesis is included.  相似文献   
422.
In the present study measurement of radon and its progeny concentration has been undertaken in the buildings constructed in the surroundings of National Hydroelectric Power Corporation (NHPC). LR-115 Type-II solid state nuclear track detectors fixed on a thick flat card were exposed in bare mode. Track etch technique has been used to estimate the radon concentration in the rooms of some buildings. Annual effective dose has been calculated from the radon concentration to carry out the assessment of the variability of expected radon exposure of the population due to radon and its progeny. The radon levels in these dwellings vary from 9±4 to 472±28 Bq m−3 with an average value of 158±14.9 Bq m−3 whereas annual effective dose varies from 0.1±0.04 to 7±0.4 mSv y−1 with an average value of 2.3±0.2 mSv y−1. These values are below the recommended action levels.  相似文献   
423.
We establish some fixed point theorems for fuzzy contractive and fuzzy locally contractive mappings on a compact metric space with the d-metric for fuzzy sets. Our results generalized well-known classical results of Edelstein.  相似文献   
424.
The primary aim of this article is to resolve a global optimization problem in the setting of a partially ordered set that is equipped with a metric. Indeed, given non-empty subsets A and B of a partially ordered set that is endowed with a metric, and a non-self mapping ${S : A \longrightarrow B}$ , this paper discusses the existence of an optimal approximate solution, designated as a best proximity point of the mapping S, to the equation Sx?=?x, where S is a proximally increasing, ordered proximal contraction. An algorithm for determining such an optimal approximate solution is furnished. Further, the result established in this paper realizes an interesting fixed point theorem in the setting of partially ordered set as a special case.  相似文献   
425.
Given non-empty subsets A and B of a metric space, let ${S{:}A{\longrightarrow} B}$ and ${T {:}A{\longrightarrow} B}$ be non-self mappings. Due to the fact that S and T are non-self mappings, the equations Sx = x and Tx = x are likely to have no common solution, known as a common fixed point of the mappings S and T. Consequently, when there is no common solution, it is speculated to determine an element x that is in close proximity to Sx and Tx in the sense that d(x, Sx) and d(x, Tx) are minimum. As a matter of fact, common best proximity point theorems inspect the existence of such optimal approximate solutions, called common best proximity points, to the equations Sx = x and Tx = x in the case that there is no common solution. It is highlighted that the real valued functions ${x{\longrightarrow}d(x, Sx)}$ and ${x{\longrightarrow}d(x, Tx)}$ assess the degree of the error involved for any common approximate solution of the equations Sx = x and Tx = x. Considering the fact that, given any element x in A, the distance between x and Sx, and the distance between x and Tx are at least d(A, B), a common best proximity point theorem affirms global minimum of both functions ${x{\longrightarrow}d(x, Sx)}$ and ${x{\longrightarrow}d(x, Tx)}$ by imposing a common approximate solution of the equations Sx = x and Tx = x to satisfy the constraint that d(x, Sx) = d(x, Tx) = d(A, B). The purpose of this article is to derive a common best proximity point theorem for proximally commuting non-self mappings, thereby producing common optimal approximate solutions of certain simultaneous fixed point equations in the event there is no common solution.  相似文献   
426.
Clustering phenomenon has been studied in a film-deposition model in which a monolayer of particles is deposited onto a substrate. The occupation of a given site is assumed to depend on the occupation states of its nearest neighbouring sites as well as on the temperature of the particles being deposited. It is found that the percolating clusters remain ramified in that the number of their boundary sites are proportional to the number of particles in the cluster. The percolation threshold, however is lowered to (54±2)% as compared to 59% density for the uncorrelated case.  相似文献   
427.
    
A screening design is an experimental plan used for identifying the expectedly few active factors from potentially many. In this paper, we compare the performances of 3 experimental plans, a Plackett‐Burman design, a minimum run resolution IV design, and a definitive screening design, all with 12 and 13 runs, when they are used for screening and 3 out of 6 factors are active. The functional relationship between the response and the factors was allowed to be of 2 types, a second‐order model and a model with all main effects and interactions included. D‐efficiencies for the designs ability to estimate parameters in such models were computed, but it turned out that these are not very informative for comparing the screening performances of the 2‐level designs to the definitive screening design. The overall screening performance of the 2‐level designs was quite good, but there exist situations where the definitive screening design, allowing both screening and estimation of second‐order models in the same operation, has a reasonable high probability of being successful.  相似文献   
428.
429.
    
Image encryption based on elliptic curves (ECs) is emerging as a new trend in cryptography because it provides high security with a relatively smaller key size when compared with well-known cryptosystems. Recently, it has been shown that the cryptosystems based on ECs over finite rings may provide better security because they require the computational cost for solving the factorization problem and the discrete logarithm problem. Motivated by this fact, we proposed a novel image encryption scheme based on ECs over finite rings. There are three main steps in our scheme, where, in the first step, we mask the plain image using points of an EC over a finite ring. In step two, we create diffusion in the masked image with a mapping from the EC over the finite ring to the EC over the finite field. To create high confusion in the plain text, we generated a substitution box (S-box) based on the ordered EC, which is then used to permute the pixels of the diffused image to obtain a cipher image. With computational experiments, we showed that the proposed cryptosystem has higher security against linear, differential, and statistical attacks than the existing cryptosystems. Furthermore, the average encryption time for color images is lower than other existing schemes.  相似文献   
430.
    
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has stressed the global health system to a significant level, which has not only resulted in high morbidity and mortality but also poses a threat for future pandemics. This situation warrants efforts to develop novel therapeutics to manage SARS-CoV-2 in specific and other emerging viruses in general. This study focuses on SARS-CoV2 RNA-dependent RNA polymerase (RdRp) mutations collected from Saudi Arabia and their impact on protein structure and function. The Saudi SARS-CoV-2 RdRp sequences were compared with the reference Wuhan, China RdRp using a variety of computational and biophysics-based approaches. The results revealed that three mutations—A97V, P323I and Y606C—may affect protein stability, and hence the relationship of protein structure to function. The apo wild RdRp is more dynamically stable with compact secondary structure elements compared to the mutants. Further, the wild type showed stable conformational dynamics and interaction network to remdesivir. The net binding energy of wild-type RdRp with remdesivir is -50.76 kcal/mol, which is more stable than the mutants. The findings of the current study might deliver useful information regarding therapeutic development against the mutant RdRp, which may further furnish our understanding of SARS-CoV-2 biology.  相似文献   
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