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121.
研究了负P表示非经典光场的Wehrl熵和Shannon熵与场参数m和平均光子数(-n)的关系,结果显示,负P表示的非经典光场的Wehrl熵随着场参数m和平均光子数的增大而减小,当(-n)增大到一定程度时Wehrl熵趋向于一个不变的常数.用数值计算的方法研究了负P表示光场的Shannon熵与平均光子数(-n)的关系,结果表明,Shannon熵随着场参数m和平均光子数(-n)的增大而增大.同时发现,Wehrl熵随光场总噪声的增大而减小,Shannon熵随力学量起伏的减小而减小. 相似文献
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123.
Zelong Gong Xuefeng Gao Qingqing Yang Jingxian Lun Hansen Xiao Jiayu Zhong Hong Cao 《Molecules (Basel, Switzerland)》2022,27(13)
Enterovirus 71 (EV71) is a dominant pathogenic agent that may cause severe central nervous system (CNS) diseases among infants and young children in the Asia-pacific. The inflammasome is closely implicated in EV71-induced CNS injuries through a series of signaling pathways. However, the activation pathway of NLRP3 inflammasome involved in EV71-mediated CNS injuries remains poorly defined. In the studies, EV71 infection, ERK1/2 phosphorylation, and activation of NLRP3 are abolished in glioblastoma cells with low vimentin expression by CRISPR/Cas9-mediated knockdown. PD098059, an inhibitor of p-ERK, remarkably blocks the vimentin-mediated ERK1/2 phosphorylation in EV71-infected cells. Nuclear translocation of NF-κB p65 is dependent on p-ERK in a time-dependent manner. Moreover, NLRP3 activation and caspase-1 production are limited in EV71-infected cells upon the caffeic acid phenethyl ester (CAPE) administration, an inhibitor of NF-κB, which contributes to the inflammasome regulation. In conclusion, these results suggest that EV71-mediated NLRP3 inflammasome could be activated via the VIM-ERK-NF-κB pathway, and the treatment of the dephosphorylation of ERK and NF-κB inhibitors is beneficial to host defense in EV71-infected CNS. 相似文献
124.
125.
Yongqing Cai Tao Xie Huan Yang Dingsong Wu Jianwei Huang Wenshan Hong Lu Cao Chang Liu Cong Li Yu Xu Qiang Gao Taimin Miao Guodong Liu Shiliang Li Li Huang Huiqian Luo Zuyan Xu Hongjun Gao Lin Zhao X.J.Zhou 《中国物理快报》2021,(5):138-143
High resolution angle-resolved photoemission spectroscopy(ARPES) measurements are carried out on CaKFe_4 As_4,KCa_2 Fe_4 As_4 F_2 and(Ba_(0.6)K_(0.4))Fe_2 As_2 superconductors.Clear evidence of band folding between the Brillouin zone center and corners with a(π,π) wave vector has been found from the measured Fermi surface and band structures in all the three kinds of superconductors.A dominant ~(1/2)×~(1/2) surface reconstruction is observed on the cleaved surface of CaKFe_4As_4 by scanning tunneling microscopy(STM) measurements.We propose that the commonly observed ~(1/2)×~(1/2) reconstruction in the FeAs-based superconductors provides a general scenario to understand the origin of the(π,π) band folding.Our observations provide new insights in understanding the electronic structure and superconductivity mechanism in iron-based superconductors. 相似文献
126.
Shaochuan Li Caiping Liu Qihui Chen Feilong Jiang Daqiang Yuan Qing-Fu Sun Maochun Hong 《Chemical science》2022,13(31):9016
Coordination hosts based on flexible ligands have received increasing attention due to their inherent adaptive cavities that often show induced-fit guest binding and catalysis like enzymes. Herein, we report the controlled self-assembly of a series of homo/heterometallic coordination hosts (Me4enPd)2n(ML)n [n = 2/3; M = Zn(ii)/Co(ii)/Ni(ii)/Cu(ii)/Pd(ii)/Ag(i); Me4en: N,N,N′,N′-tetramethylethylenediamine] with different shapes (tube/cage) from a flexible tetraazacyclododecane-based pyridinyl ligand (L) and cis-blocking Me4enPd(ii) units. While the Ag(i)-metalated ligand (AgL) gave rise to the formation of a (Me4enPd)4(ML)2-type cage, all other M(ii) ions led to isostructural (Me4enPd)6(ML)3-type tubular complexes. Structural transformations between cages and tubes could be realized through transmetalation of the ligand. The buffering effect on the ML panels endows the coordination tubes with remarkable acid–base resistance, which makes the (Me4enPd)6(ZnL)3 host an effective catalyst for the CO2 to CO32− conversion. Control experiments suggested that the integration of multiple active Zn(ii) sites on the tubular host and the perfect geometry match between CO32− and the cavity synergistically promoted such a conversion. Our results provide an important strategy for the design of adaptive coordination hosts to achieve efficient carbon fixation.A series of coordination hosts were prepared and their applications in CO2 fixation were studied. 相似文献
127.
MAIO Hong GAO Chong-Shou ZHUANG Peng-Fei 《理论物理通讯》2006,46(12)
Bound states, such as qq and q(q), may exist in quark-gluon plasma. As the system is at high density,the volume of the bound states may evoke a reduction in the phase space. We introduce an extended bag model to investigate qualitatively the volume effect on the properties of the system. We find a limit temperature where the bound states start to be completely melted. 相似文献
128.
129.
一步法直接合成碳酸二甲酯催化剂 总被引:5,自引:0,他引:5
采用浸渍法以MgO、海泡石(Sep)。γ-Al2O3为载体,制备了一系列金属盐Lewis酸-无机碱双组分负载型催化剂,以环氧丙烷(PO)一步合成碳酸二甲酯(DMC)反应为探针。考察了催化剂的不同载体活性组分和反应条件对合成DMC的产率及选择性的影响。结果表明,催化剂的活性次序为:NaOH—LiCl/MgO)NaOH—LiCl/Sep)NaOH—LiCl/γ-Al2O3;选择性的次序为:NaOH—LiCl/Sep)NaOH—LiCl/MgO)NaOH—LiCl/γ-Al2O3。NaOH—LiCl/SeP催化剂具有较高的活性和选择性;其最佳反应条件为:反应温度160℃。反应时间5h,甲醇与PO的量之比为1:1。在最佳条件下。PO转化率为82.6%,DMC的产率达到7.68%。 相似文献
130.
Yi Wang Xiangli Zhang Wenya Zhuang Yanlei Yu Xuanrong Sun Hong Wang Fengzhi Li Qingyong Li 《Molecules (Basel, Switzerland)》2022,27(12)
Irinotecan and Topotecan are two Camptothecin derivatives (CPTs) whose resistance is associated with the high expression of breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp). To reverse this resistance, two novel CPTs, FL77-28 (7-(3-Fluoro-4-methylphenyl)-10,11-methylenedioxy-20(S)-CPT) and FL77-29 (7-(4-Fluoro-3-methylphenyl)-10,11-methylenedioxy-20(S)-CPT), were synthesized by our group. In this study, the anti-tumor activities of FL77-28, FL77-29, and their parent, FL118 (10,11-methylenedioxy-20(S)-CPT), were evaluated and the results showed that FL77-28 and FL77-29 had stronger anti-tumor activities than FL118. The transport and uptake of FL118, FL77-28, and FL77-29 were investigated in Caco-2 cells for the preliminary prediction of intestinal absorption. The apparent permeability coefficient from apical to basolateral (Papp AP-BL) values of FL77-28 and FL77-29 were (2.32 ± 0.04) × 10−6 cm/s and (2.48 ± 0.18) × 10−6 cm/s, respectively, suggesting that the compounds had moderate absorption. Since the transport property of FL77-28 was passive diffusion and the efflux ratio (ER) was less than 2, two chemical inhibitors were added to further confirm the involvement of efflux proteins. The results showed that FL77-28 was not a substrate of P-gp or BCRP, but FL77-29 was mediated by P-gp. In conclusion, FL77-28 might be a promising candidate to overcome drug resistance induced by multiple efflux proteins. 相似文献