The alkaloids from the fruits of the plant Daphniphyllaceae

Six alkaloids have been isolated from the fruits of the plant Daphniphyllaceae. Two of them are new alkaloids, namely methyl homodaphniphyllate (1) and daphnilactone-B (2). The structure of the former was deduced by chemical transformation from daphniphylline (3). The structure of daphnilactone-B was estimated by the exhaustive spectral analysis as well as by chemical evidences, and finally determined by an X-ray crystallographic analysis of the free base.     

Preparation of trimethylsilyl derivatives of amino acids and peptides for peptide synthesis

Russian Chemical Bulletin -     

Darstellung,Schwingungsspektren und Struktur von Oxotetrafluorovanadaten MIVOF4 (MI = Na,K, Rb,Cs, Tl, (CH3)4N)

Preparation, Vibrational Spectra, and Structure of Oxotetrafluorovanadates M^IVOF₄ (M^I = Na, K, Rb, Cs, Tl, (CH₃)₄N) The compounds M^IVOF₄ (M^I = K, Rb, Cs, Tl) and M^IVOF₄ · H₂O (M^I = Na, (CH₃)₄N) have been prepared. The crystal structure of KVOF₄ has been determined by single crystal X-ray diffraction. The VOF-ions form endless chains by fluorine bridges. The lengths of the bridge bonds are 1.875(7) and 2.333(7) Å. The terminal V? O- and V? F-distances are 1.572(8) and 1.793 Å (mean value), respectively. The vibrational spectra have been registered and assigned.     

Hydrocarbomethoxylation of 1-hexene with formic acid and methanol under conditions of phosphoric acid catalysis

Conclusions When the hydrocarbomethoxylation of 1-hexene with formic acid is run at atmospheric pressure and temperatures close to room temperature, in the presence of conc. H₃PO₄, an increase in the relative amount of the latter, as well as an increase in the reaction temperature in the investigated range, both favor an increase in the yields of the methyl esters of the C₇ acids, in particular, those containing two methyl groups on the quaternary carbon atom in the -position. An increase in the relative amount of formic acid also favors an increase in the amounts of these esters in the obtained mixtures of esters.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1116–1118, May, 1971.     

Hydrolysis of furan and 5-nitrofuran penicillins by penicillinase Bacillus licheniformis

The enzymatic hydrolysis of various furan and 5-nitrofuran penicillins by penicillinaseBacillus licheniformis 749/c was investigated. The effect of various side-chain structural groupings on the rate of inactivation of these compounds was studied. The introduction of bulky substituents in the ortho or positions to the amide group and lengthening the side chain or increasing its degree of unsaturation sharply decrease the catalytic action of penicillinase and, consequently, the rate of cleavage of the-lactam ring of the antibiotic. The majority of the furan and 5-nitrofuran penicillins surpass benzylpenicillin in resistance to the enzyme but are inferior to methicillin and oxacillin.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 295–298, March, 1971