An effective synthesis method for secondary fluorinated alcohols via the reaction of esters of polyfluorinated acids with trialkylalanes

Unlike nonfluorinated analogs, complex esters of polyfluorinated acids in reactions with trialkylalanes produce only polyfluorinated secondary alcohols.Department of Fine Organic Synthesis, Institute of Organic Chemistry, Urals Branch, Russian Academy of Sciences, 450054 Ufa. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 10, pp. 2339–2341, October, 1992.     

A multi-objective integrated facility location-hardening model: Analyzing the pre- and post-disruption tradeoff

Two methods of reducing the risk of disruptions to distribution systems are (1) strategically locating facilities to mitigate against disruptions and (2) hardening facilities. These two activities have been treated separately in most of the academic literature. This article integrates facility location and facility hardening decisions by studying the minimax facility location and hardening problem (MFLHP), which seeks to minimize the maximum distance from a demand point to its closest located facility after facility disruptions. The formulation assumes that the decision maker is risk averse and thus interested in mitigating against the facility disruption scenario with the largest consequence, an objective that is appropriate for modeling facility interdiction. By taking advantage of the MFLHP’s structure, a natural three-stage formulation is reformulated as a single-stage mixed-integer program (MIP). Rather than solving the MIP directly, the MFLHP can be decomposed into sub-problems and solved using a binary search algorithm. This binary search algorithm is the basis for a multi-objective algorithm, which computes the Pareto-efficient set for the pre- and post-disruption maximum distance. The multi-objective algorithm is illustrated in a numerical example, and experimental results are presented that analyze the tradeoff between objectives.     

Laser Diode-Pumped Nd：LuVO4 Acousto-Optic Q-Switched Laser at 916 nm

A compact laser diode-pumped solid-state Nd：LuVO4 acousto-optic Q-switched laser is demonstrated at 916 nm of a quasi-three level for the first time. A pulse width of 130ns is observed when the pulse-repetition frequency is 10 kHz. The laser experiment shows that the Nd：Lu VO4 crystal can be used for efficient diode-pumped Q-switched lasers.     

内蒙古地区沙生植物--沙枣中维生素C含量的测定

在 pH 6.0的 HAc-NaAc缓冲溶液中,用活性炭吸附沙枣中的色素,Cu(Ⅱ)催化氧化维生素C,在λmax=268 nm处可直接测定沙枣中维生素C含量.与传统碘量法相比,测定结果基本一致.为内蒙古地区沙枣天然植物资源的药用开发、食品加工等提供了参考数据.     

Radical polymeric photoinitiators bearing side‐chain camphorquinone moieties linked to the main chain through a flexible spacer

New polymeric photoinitiators bearing the side‐chain camphorquinone moiety spaced from the backbone by a long and flexible connection have been prepared and tested in the photocuring of acrylic monomers upon irradation with visible light in the presence of tertiary amine coinitiator. The results indicate that the photoinitiating activity of the polymeric initiators may be comparable to the related combination of low molecular weight derivatives when the camphorquinone component has a polymeric structure, and depends on the chemical structure of both the components of the initiator/coinitiator pair. © 2005 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 5879–5888, 2005     

Predicting the Performance of Granulation Binders Through Micro‐Mechanistic Observations

The selection of an appropriate polymeric binder to be used to agglomerate drug with excipients is a critical issue for the development of high shear wet granulation processes for pharmaceutical tablet systems. The aim of the study reported here is to determine the potential for successful granulation through measurement of the interactions of two polymer binder solutions, hydroxypropyl methylcellulose (HPMC) and polyvinyl‐pyrrolidone (PVP), with individual paracetamol drug crystals. A novel micro‐force balance (MFB) has been used to measure different parameters of the crystal‐to‐binder interaction, including the forces exerted by axially strained liquid bridges formed between either two paracetamol crystals or between a reservoir of binder solution and a single paracetamol crystal, the paracetamol‐to‐binder wettability, the post rupture volume distribution and the residue deposited on each crystal. Video images of the separation sequences were obtained simultaneously for analysis of bridge geometry, contact angles, volume distribution and binder residues. It was found that the formation of liquid bridges and their ability to bond particles together depends on the amount of binder left on a crystal after contacting a reservoir of binder (for example, large binder drop). Crystals in contact with HPMC were able to retain more liquid from a binder reservoir than those contacted with PVP solutions. This behaviour is seen to be more important to the final granule strength than the liquid binding force holding particles together in the wet agglomerate.     

Pulse behaviour of a compact RF discharged CO2 slab laser

We present the measurements made on a medium power, 35 cm long, radio-frequency discharge CO₂ slab laser operated in a pulsed regime obtained by switching the RF discharge. In this way, pulses with peak power up to 480 W at pulse repetition frequencies in the range 1 to 10 kHz have been obtained. Pulse energy and average extracted power have been experimentally characterized with respect to the pulse repetition frequency and to the pulse duration, and the pulse shape and characteristic times have been measured. We also investigated the propagation properties of the beam emerging from our laser.     

EXAFS-XANES evidence of in situ cesium reduction in Cs-Ru/C catalysts for ammonia synthesis

We present here a X-ray absorption spectroscopy (XAS) investigation on the local chemical order and electronic structure of Cs and Ba, promoters of the Ru/C catalysts for ammonia synthesis that attracted interest because of highly increased productivity. The role of the promoters is still largely unclear, although indirect evidence for Cs partial reduction has been obtained by this and other groups. Our XAS analysis with in situ H(2) reduction directly supports the partial Cs reduction in the promoted Ru/C catalysts, depending on the presence of Ru and on the graphitization degree of the support. Higher coordination of Ba was observed with respect to Cs in the reduced samples, without evidence of heavy atoms (Ru, Cs, and Ba) in the surroundings. Because of the strong electropositive nature of Cs, direct experimental evidence of its partial reduction is of outstanding significance also for other applications.     

Duty cycle and directional jet effects of a plasma actuator on the flow control around a NACA0015 airfoil

This paper reports on the effects of a series of fluid-dynamic dielectric barrier discharge plasma actuators on a NACA0015 airfoil at high angle of attack. A set of jet actuators able to produce plasma jets with different directions (vectoring effect) and operated at different on/off duty cycle frequencies are used. The experiments are performed in a wind tunnel facility. The vectorized jet and the transient of the flow induced by unsteady duty cycle operation of each actuator are examined and the effectiveness of the actuator to recover stall condition in the range of Reynolds numbers between 1.0 × 10⁵ and 5.0 × 10⁵ (based on airfoil chord), is investigated. The actuator placed on the leading edge of the airfoil presents the most effective stall recovery. No significant effects can be observed for different orientations of the jet. An increase of the stall recovery is detected when the actuator is operated in unsteady operation mode. Moreover, the frequency of the on/off duty cycle that maximizes the stall recovery is found to be a function of the free stream velocity. This frequency seems to scale with the boundary layer thickness at the position of the actuator. A lift coefficient increase at low free stream velocities appears to linearly depend on the supply voltage.