Immunoassays Based on Surface-Enhanced Fluorescence using Gap-Plasmon-Tunable Ag Bilayer Nanoparticle Films

A novel gap-plasmon-tunable Ag bilayer nanoparticle film for immunoassays is demonstrated. Different from a traditional Ag monolayer nanoparticle film, a desired number of polyelectrolyte (PEL) layers are deposited on the nanoparticles before the self-assembly of a second Ag nanoparticle layer. Interestingly, by controlling the number of the PEL interlayers, the gap plasmon between the two Ag nanoparticle layers can be tuned across the visible spectral range. The ability of the presented Ag bilayer nanoparticle films in fluorescence enhancement has been examined experimentally. A maximal enhancement of around 15.4 fold was achieved when 7 layers of polyelectrolyte were used. When this optimal Ag bilayer nanoparticle film was applied to fluorescence immunoassay, a performance with approximately 3.3-fold enhancement was obtained compared with that performed on a traditional glass substrate. The experimental results suggest that the presented gap-plasmon tunable Ag bilayer nanoparticle films have great potential in fluorescence-based immunoassays. The method of the bilayer-film construction presented here also provides new insights into the rational design of the plasmonic substrates.     

有ITO透明导电膜的平面分层介质系统的电磁波性能理论研究

理论研究了有ITO(indium tin oxide)透明导电膜的多层平面分层介质系统的电磁性能，给出的理论曲线和实测曲线符合很好.多层平面分层介质系统的电磁性能与ITO膜(方块电阻为8Ω)所在界面位置和平面分层介质系统层数及各层厚度等有关.优化设计了一种含有ITO透明导电膜的厚度仅7.35mm的四层平面分层介质系统，其在8—18GHz频段内电磁波反射性能很好.作为多层平面分层系统中的ITO导电膜，其方块电阻应低于30Ω，并且越小，其反射性能越好. 关键词： 多层平面介质系统 电磁性能 ITO透明导电膜     

Impurity effects of the Λhyperon in the hypernuclear systems ${}_{{\rm{\Lambda }}}^{25}\mathrm{Mg}$ and ${}_{{\rm{\Lambda }}}^{29}\mathrm{Si}$

Based on the beyond-mean-field Skyrme–Hartree–Fock model, impurity effects of the Λhyperon in the hypernuclear systems ${}_{\,{\rm{\Lambda }}}^{25}$ Mg and ${}_{\,{\rm{\Lambda }}}^{29}$ Si are investigated, respectively. Four cases, in which the Λhyperon occupies the single-particle orbitals ${\rm{\Lambda }}$[000]${\tfrac{1}{2}}^{+}$, ${\rm{\Lambda }}$[110]${\tfrac{1}{2}}^{-}$, ${\rm{\Lambda }}$[101]${\tfrac{3}{2}}^{-}$ and ${\rm{\Lambda }}$[101]${\tfrac{1}{2}}^{-}$, are focused. In each case, the potential energy surface and the energy curves projected on certain angular momenta are employed to show the influence of the Λhyperon on the nuclear core. Beside the shrinkage effect that is induced by the Λhyperon occupying the s_Λ orbital, it is found that the Λhyperon on the p_Λ orbital, ${\rm{\Lambda }}$[110]${\tfrac{1}{2}}^{-}$, drives the nuclear core toward a prolate shape, while the ones on the other two p_Λ orbitals, ${\rm{\Lambda }}$[101]${\tfrac{3}{2}}^{-}$ and ${\rm{\Lambda }}$[101]${\tfrac{1}{2}}^{-}$, drive the nuclear core toward an oblate shape. The energy spectra and the corresponding intra-band E2 transition rates for the rotational bands are given as a prediction for future experiments.     

In-medium pion dispersion relation and medium correction of Nπ■Δ near the threshold energy of pion production

Transport models cannot simultaneously explain very recent data on pion multiplicities and pion charged ratios from central collision of Sn+Sn at 0.27 A GeV.This stimulates further investigations on the pion dispersion relation,in-medium Nπ→Δ cross sections,and Δ→Nπ decay widths near the threshold energy or at subthreshold energy of pion production in isospin asymmetric nuclear matter.In this study,the pion dispersion relation,in-medium Nπ→Δ cross section,and Δ→Nπ decay width near the threshold energy are investigated in isospin asymmetric nuclear matter by using the one-boson-exchange model.With the consideration of the energy conservation effect,the in-medium Nπ→Δ cross sections are enhanced at s1/2 <1.11 GeV in a nuclear medium.The prediction of pion multiplicity and π-/π+ ratios near the threshold energy could be modified if this effect is considered in transport model simulations.     

Analysis of Electromagnetic Information Leakage Based on Cryptographic Integrated Circuits

Cryptographic algorithm is the most commonly used method of information security protection for many devices. The secret key of cryptographic algorithm is usually stored in these devices’ registers. In this paper, we propose an electromagnetic information leakage model to investigate the relationship between the electromagnetic leakage signal and the secret key. The registers are considered as electric dipole models to illustrate the source of the electromagnetic leakage. The equivalent circuit of the magnetic field probe is developed to bridge the output voltage and the electromagnetic leakage signal. Combining them, the electromagnetic information leakage model’s function relationship can be established. Besides, an electromagnetic leakage model based on multiple linear regression is proposed to recover the secret key and the model’s effectiveness is evaluated by guess entropy. Near field tests are conducted in an unshielded ordinary indoor environment to investigate the electromagnetic side-channel information leakage. The experiment result shows the correctness of the proposed electromagnetic leakage model and it can be used to recover the secret key of the cryptographic algorithm.     

Electrostatic potential in cylindrical dielectric media using the image charge method

We derive a simple analytical expression for the electric potential produced by a point charge in a cylindrical pore with relative permittivity different from that of the surrounding medium. The interface between the pore and the surrounding media may contain electric charge or be electrically neutral. The expression reduces to the known solutions when the surrounding dielectric medium is identical to the pore or an electric conductor. We discuss the convergence of the series expansion and numerically evaluate the electrostatic potential inside the cylindrical pore. The calculated potential shows the effect of the dielectric permittivity difference of the media. The results demonstrate that the expression can be implemented in a numerical dynamic simulation of charged systems in cylindrical geometry. We also give an expression for the case when the source charge is in the medium outside the cylinder.     

Interaction Between Neuroglobin and Caffeine by Multispectroscopic Methods

The interaction between neuroglobin (Ngb) and caffeine was studied by spectroscopy. UV-Vis spectra revealed that caffeine did not influence the native hexa-coordinated heme structure of neuroglobin. Fluorescence spectra indicated that caffeine could quench the intrinsic fluorescence of neuroglobin through static quenching mechanisms. The calculated thermodynamic parameters showed that the electrostatic force was the main intermolecular force in the reaction. Results also indicated that the microenvironmental changes of tryptophan and tyrosine residues within neuroglobin are inapparent. Furthermore, the circular dichroism (CD) spectra implied that caffeine could induce the formation of α-helix structure of neuroglobin.     

An improved evaluation of the neutron background in the PandaX-Ⅱ experiment

In dark matter direct detection experiments,neutron is a serious source of background,which can mimic the dark matter-nucleus scattering signals.In this paper,we present an improved evaluation of the neutron background in the PandaX-II dark matter experiment by a novel approach.Instead of fully relying on the Monte Carlo simulation,the overall neutron background is determined from the neutron-induced high energy signals in the data.In addition,the probability of producing a dark-matter-like background per neutron is evaluated with a complete Monte Carlo generator,where the correlated emission of neutron(s)andγ(s)in the(α,n)reactions and spontaneous fissions is taken into consideration.With this method,the neutron backgrounds in the Run 9(26-ton-day)and Run 10(28-ton-day)data sets of PandaX-II are estimated to be(0.66±0.24)and(0.47±0.25)events,respectively.     

相对性区域创新指数与经济周期挖掘

提出了一类新的相对性区域创新指数,并采用世界专利申请数据对其进行了具体计算.基于区域创新同经济发展水平之间的超线性关系,该指数消除了经济发展水平对创新能力的影响,可以实现对不同发展水平的经济体之间进行有效的创新能力横纵对比.该创新指数尽管极其简单,却揭示出一系列迥异于传统认知的现象,例如中国大陆地区的技术创新能力在1980年代就已经位居世界前列.采用该指数,不但可以在较高水平上解释世界各国的经济增长,还发现它同经济增长率之间的相关性存在一个20年的经济周期.这些结果显示,该指数作为一个单一性指标,以极小的数据依赖就实现了较高程度的解释性,不但重新定位了世界各经济体的创新能力,对深入理解创新同经济发展之间的关系提供了新的角度,而且暗示着这类相对性经济指标的发展潜力与应用空间.