Reliability of high‐resolution electron backscatter diffraction determination of strain and rotation variations using phase‐only and cross correlation

This contribution analyzes the reliability of strain and rotation variation determination using cross‐ as well as phase‐only correlation of experimental wide‐angle electron backscatter diffraction (EBSD) patterns. For both rotation and three‐point bending the resulting displacement gradient tensor components are examined in terms of magnitude and statistical scatter as a function of various correlation procedure parameters and signal‐to‐noise ratio. It is shown that on the one hand the Fourier filter width has a major impact on the strain results. At higher noise level a smaller filter width has to be applied for obtaining maximum precision. On the other hand, the influence of the degree of overlap of the regions of interest positioned in the patterns is less important. For both rotation and bending experiments the cross‐correlation variant yields a smaller standard deviation with respect to phase‐only correlation, in particular for elevated noise level. The difference is attributed to the stronger propagation of noise effects in the course of phase‐only correlation function calculation and fitting. In the rotation experiment a standard deviation of ∼1.0 × 10⁻⁴, averaged over the displacement gradient tensor components, and a rotational precision of ∼1.5 × 10⁻⁴ rad have been achieved by using optimized evaluation settings.     

Von Steinkohlenteer bis zu Krebsmedikamenten

When Friedrich Bayer and Johann Friedrich Weskott laid foundation for todays Bayer group, they initially exclusively focused on dyestuffs. However coal tar, which formed the common basis for these dystuffs, offered further opportunities for its application: from crop protection agents across antipyretic medicines up to anti‐cancer drugs. By means of exemplarily chosen chemical substances and their history of development – from the early days until today – the corporate history of Bayer is illustrated.     

Cyclizations to new azolopyridazines and related ring systems

In the course of our recent synthetic activity in the area of ring closure reactions we have found that relatively little had been published on azolopyridazines and related compounds, and this circumstance prompted us to explore novel pathways to such ring systems. In the present short review three such approaches from our laboratory leading to various fused azoles are discussed.     

Synthese des 1-(2,3-Dimethoxybenzyl)-5,6-dimethoxyisochinolins

Ohne Zusammenfassung     

VIER- UND FÜNFGLIEDRIGE PHOSPHORHETEROCYCLEN,XVI 1.3.4.2Λ3-OXADIAZAPHOSPHOLINE

Abstract

Die Kondensation von N ¹-substituierten N-Acetyl-und-Benzoyl-hydrazinen mit P[N(CH₃)₂]₃ oder CH₃P[NCH₃)₂]₂ fuhrt stets zu 3-substituierten 1.3.4.2Λ³-Oxadizaphospholinen, auch wenn der jeweilige Substituent die Bildung von anderen isomeren Fünfringen oder von Isomeren mit größerem Ring oder eine weitergehende Kondensation zuließe. Sie können in die 2.2-Dichloro- und 2-Thioxo-1.3.4.2Λ⁵-Oxadiazaphospholine übergeführt werden.

Condensation of N ¹-substituted N-acetyl and N-benzoyl hydrazines with P[N(CH₃)₂]₃ or CH₃P[N(CH₃)₂] 2 always gives 3-substituted 1.3.4.2Λ3-oxadiazaphospholines, even if the substituent would allow other isomeric five membered or larger ring phosphorus heterocycles to be formed, or the condensation to proceed further. The title compounds can be oxidized to 2.2-dichloro and 2-thioxo 1.3.4.2Λ⁵-oxadiazaphospholines.     

New approach for the synthesis of 3H-pyrrolo[2,3-c]isoquinoline derivatives

Synthesis of new 2,3-diaryl-3H-pyrrolo[2,3-c]isoquinoline derivatives has been elaborated starting from isoquinoline-3-amine. Buchwald–Hartwig arylation and subsequent iodination in position 4 afforded 3-arylamino-4-iodoisoquinolines. These compounds were subjected to Sonogashira cross-coupling reactions with some selected acetylenes, and the resulting coupled products underwent cyclization in the presence of tetrabutylammonium fluoride to give title derivatives.     

Literatur

Ohne Zusammenfassung     

Prospects of open charm production at GSI-FAIR and J-PARC

We present a detailed phenomenological study of the prospects of open charm physics at the future p̄p and pp facilities GSI-FAIR and J-PARC, respectively. In particular, we concentrate on the differential cross sections and the charge and longitudinal double-spin asymmetries at next-to-leading order accuracy. Theoretical uncertainties for the proposed observables are estimated by varying the charm quark mass and the renormalization and factorization scales. PACS 12.38.Bx; 13.88.+e