Photooxidation of 2,3-dihydroquinazolin-4(1H)-ones: retention or elimination of 2-substitution

Molecular Diversity - A series of mono and disubstituted 2,3-dihydroquinazolin-4(1H)-ones (DHQZs) were synthesized and the electronic and steric effects of the C2- and N3-substitutions on the...     

Analysis of non-pharmaceutical interventions impacts on COVID-19 pandemic in Iran

The COVID-19 pandemic shows to have a huge impact on people's health and countries' infrastructures around the globe. Iran was one of the first countries that experienced the vast prevalence of the coronavirus outbreak. The Iranian authorities applied various non-pharmaceutical interventions to eradicate the epidemic in different periods. This study aims to investigate the effectiveness of non-pharmaceutical interventions in managing the current Coronavirus pandemic and to predict the next wave of infection in Iran. To achieve the research objective, the number of cases and deaths before and after the interventions was studied and the effective reproduction number of the infection was analyzed under various scenarios. The SEIR generic model was applied to capture the dynamic of the pandemic in Iran. To capture the effects of different interventions, the corresponding reproduction number was considered. Depending on how people are responsive to interventions, the effectiveness of each intervention has been investigated. Results show that the maximum number of the total of infected individuals will occur around the end of May and the start of June 2021. It is concluded that the outbreak could be smoothed if full lockdown and strict quarantine continue. The proposed modeling could be used as an assessment tool to evaluate the effects of different interventions in new outbreaks.

     

Correction to: Synthesis and antibacterial study of 2-amino-4H-pyrans and pyrans annulated heterocycles catalyzed by sulfated polysaccharide-coated BaFe12O19 nanoparticles

Research on Chemical Intermediates -     

Design of the novel calix[n]BODIPY molecules (n = 4–8): TDDFT and AIM study

Journal of Inclusion Phenomena and Macrocyclic Chemistry - In this study, based on BODIPY molecule, new calix-like structures with significant electrical and optical properties were designed. These...     

MnSb2O6-chitosan nanocomposite: An efficient catalyst for the synthesis of coumarins via Pechmann reaction

In this work, MnSb₂O₆-chitosan nanocomposites were synthesized and have been employed in Pechmann condensation for the synthesis of coumarin derivatives. MnSb₂O₆-chitosan nanocomposites were characterized by Fourier transform infrared (FTIR), X-ray powder diffraction (XRD), scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDX) techniques. The particles of MnSb₂O₆-chitosan have uniform spheres with sizes that are less than 100 nm. Simplicity, easy work-up, and short reaction times are advantages of this reaction. Also, we evaluated the antibacterial activity for some of the products, and the result showed significant pharmaceutical activities as antibacterial reagents against Staphylococcus aureus and Escherichia coli.     

Ferric (III) complex supported on superparamagnetic Fe3O4@SiO2 as a reusable Lewis acid catalyst: a new highly efficient protocol for the synthesis of acridinedione and spiroquinazolin-4(3H)-one derivatives

Research on Chemical Intermediates - Nano-Fe3O4@SiO2-3,4-dihydroxybenzaldehyde/barbituric acid/phthalhydrazide-FeCl3 (nano-Fe3O4@SiO2-HBP-FeCl3) was prepared and authenticated by usual analytical...     

Empirical correlations development for heat transfer and friction factor of a solar rectangular air passage with spherical-shaped turbulence promoters

Journal of Thermal Analysis and Calorimetry - A study was conducted to enhance the thermo-hydraulic performance of a rectangular solar air passage with integrated spherical-shaped turbulence...     

Numerical simulation of critical heat flux in forced boiling of a flow in an inclined tube with different angles

Journal of Thermal Analysis and Calorimetry - In this paper, the effect of changing tube slope on the critical heat flux for the evaporation of upward saturated flow of a liquid (water) in a...     

Synthetic fluorescent probes to apprehend calcium signalling in lipid droplet accumulation in microalgae——an updated review

Lipid bodies are dynamic organelles of photosynthetic microalgae that can be used as the third generation resources for biofuel production.Biosynthesis of lipids can be influenced by different signalling processes.Visualisation of these processes can provide useful information about the fate and associated roles of lipid molecules in different biological systems.In photosynthetic organisms,however,studies of calcium ediated lipid biosynthesis is bottlenecked due to the limitation of proper and efficient technologies,which also include visualisation techniques.Currently,most studies to visualise lipid droplets in vivo have used traditional dyes,and proper visualisation of lipid drops is hindered by dye-specific limitations.This hurdle could be overcome by using recently developed aggregation-induced emission biooprobes.This review reveals current knowledge gaps in the studies of lipid drops and calcium ions in microalgae,as calcium signaling is important secondary messenger to detect a wide variety of environmental stimuli in plant and animal cells.To obtain insight into the mechanisms of these processes,the merits and demerits of currently available visualisation techniques for lipid drops and calcium are also detailed.Finally,opportunities and possibilities are proposed to recommend further improvement of techniques for detecting the role of calcium during lipid formation in microalgae for biofuel production.