Selective Uptake of Cylindrical Poly(2‐Oxazoline) Brush‐AntiDEC205 Antibody‐OVA Antigen Conjugates into DEC‐Positive Dendritic Cells and Subsequent T‐Cell Activation

To achieve specific cell targeting by various receptors for oligosaccharides or antibodies, a carrier must not be taken up by any of the very many different cells and needs functional groups prone to clean conjugation chemistry to derive well‐defined structures with a high biological specificity. A polymeric nanocarrier is presented that consists of a cylindrical brush polymer with poly‐2‐oxazoline side chains carrying an azide functional group on each of the many side chain ends. After click conjugation of dye and an anti‐DEC205 antibody to the periphery of the cylindrical brush polymer, antibody‐mediated specific binding and uptake into DEC205⁺‐positive mouse bone marrow‐derived dendritic cells (BMDC) was observed, whereas binding and uptake by DEC205^? negative BMDC and non‐DC was essentially absent. Additional conjugation of an antigen peptide yielded a multifunctional polymer structure with a much stronger antigen‐specific T‐cell stimulatory capacity of pretreated BMDC than application of antigen or polymer–antigen conjugate.     

Methode zur Brom-Bestimmung in Woll-Textilien mittels R?ntgen-Fluoreszenz-Spektroskopie

Ohne Zusammenfassung     

A class of multidimensional periodic splines

Periodic spline functions are introduced by use of reproducing kernel structure in Hilbert spaces. Minimum properties are described in interpolation and best approximation problems. A numerical method for determining interpolating splines and best approximations is proposed.Dedicated to Prof. Dr. F. Reutter on the occasion of his 70th birthday     

Quantum information and triangular optical lattices

The regular structures obtained by optical lattice technology and their behavior are analyzed from the quantum information perspective. Initially, we demonstrate that a triangular optical lattice of two atomic species, bosonic or fermionic, can be employed to generate a variety of novel spin-1/2 models that include effective three-spin interactions. Such interactions can be employed to simulate specific one-or two-dimensional physical systems that are of particular interest for their condensed matter and entanglement properties. In particular, connections between the scaling behavior of entanglement and the entanglement properties of closely spaced spins are drawn. Moreover, three-spin interactions are well suited to support quantum computing without the need to manipulate individual qubits. By employing Raman transitions or the interaction of the atomic electric dipole moment with magnetic field gradients, one can generate Hamiltonians that can be used for the physical implementation of geometric or topological objects. This work serves as a review article that also includes many new results.     

Sawtooth faceting in silicon nanowires

We observe in situ the vapor-liquid-solid (VLS) growth of Si nanowires, in UHV-CVD using Au catalyst. The nanowire sidewalls exhibit periodic sawtooth faceting, reflecting an oscillatory growth process. We interpret the facet alternation as resulting from the interplay of the geometry and surface energies of the wire and liquid droplet. Such faceting may be present in any VLS growth system in which there are no stable orientations parallel to the growth direction. The sawtooth structure has important implications for electronic mobility and scattering in nanowire devices.     

Clockwork SUSY: supersymmetric Ward and Slavnov-Taylor identities at workin Green's functions and scattering amplitudes

We study the cancellations among Feynman diagrams that implement the Ward and Slavnov-Taylor identities corresponding to the conserved supersymmetry current in supersymmetric quantum field theories. In particular, we show that the Faddeev-Popov ghosts of gauge and supersymmetries never decouple from the physical fields, even for abelian gauge groups. The supersymmetric Slavnov-Taylor identities provide efficient consistency checks for automatized calculations and can verify the supersymmetry of Feynman rules and the numerical stability of phenomenological predictions simultaneously.Received: 2 June 2003, Revised: 1 July 2003, Published online: 5 September 2003     

Instability-driven SiGe island growth

Three-dimensional islanding is generally assumed to proceed through nucleation and growth. Here we present studies showing the growth of Si1-xGex islands (0.2相似文献