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311.
Shah Saud Guoqing Li Yingjie Sun Muhammad Idrees Khan Ashfaq Ur Rehman Asad Uzzaman Weiwen Liu Chan Ding Hua Xiao Yuxing Wang Chengxi Cao 《Electrophoresis》2019,40(20):2767-2774
A novel analytical protocol was developed for general quality screening of chicken meat based on IEF and protein extraction. To demonstrate the developed protocol, 24 chickens were divided into three groups; each had eight chickens. The chickens in Group 1 were slaughtered by exsanguination, Group 2 asphyxiated in water, and that in Group 3 were infected by new castle disease virus. Proteins were extracted from the meat samples by using pure water as an extractant, separated by IEF, verified by western blot, and quantified via imaging analysis. The relevant experiments demonstrated that two myoglobin (Mb) bands were detected at pI 6.8 and 7.04 for all samples of Groups 1, 2, and 3, but there were additional hemoglobin (Hb) bands at pI 7.09 and 7.13 (P < 0.05) for the samples of Groups 2 and 3. The results implied that Hb bands might be a potential biomarker for the screening of chicken meat quality. The RSD values of two Mb bands (pI 6.8 and 7.04) in Group 1 were respectively 4.08 and 3.63%, the ones of two Hb bands (pI 7.09 and 7.13) in Group 2 were 3.66 and 2.10%, and those in Group 3 were 2.17% and 2.77%, respectively. All the RSD values indicated high stability and reliability of the developed protocol. Additionally, the protocol had a direct readout of protein bands in IEF without staining. However, it was time‐consuming and had high cost. Even so, the relevant general method and finding have potential for screening of chicken meat quality. 相似文献
312.
Kinetic theory has been applied to study the damping characteristics of dust ion acoustic waves (DIAWs) in a dusty plasma comprising q‐non‐extensive distributed electrons and ions, while the dust particles are considered extensive following the Maxwellian velocity distribution function. It is found that the results of the three‐dimensional velocity distribution function are more accurate compared to the results of the one‐dimensional velocity distribution function. The numerical solution of the dispersion relation is carried out to study the effect of the non‐extensivity parameter q on the dispersion, the damping rate, and the range of the values of the normalized wavenumber ( k λD) for which the DIAWs are weakly damped. It is found that the change in the value of the electron non‐extensivity parameter qe has a minor effect on the dispersion, the damping rate, and the range of the values of the normalized wavenumber ( k λD) for which the DIAWs are weakly damped, while on the other hand, ion non‐extensivity parameter qi has a strong effect on these arguments. The effect of other parameters, such as the ratio of electron to ion number density and ratio of electron to ion temperature, on the damping characteristics of DIAWs is also highlighted. 相似文献
313.
Mohammed Mansour Quradha Rasool Khan Mujeeb-ur- Rehman Abdulrahman Abohajeb 《Natural product research》2019,33(17):2554-2559
Chemical composition, antioxidant, anticancer, and antimacrobial activities of essential oil obtained from leaves of Rumex nervosus has been evaluated here for the first time. GC/MS analysis reveals the presence of Palmitoleic Acid (28.35%) and Palmitic acid, (25. 37%) as their methyl ester as major components. The essential oil showed significant DPPH radical scavenging activity (94.907 ± 0.1089% and 94.003 ± 0.0749%) at concentration (100 and 80) μg/mL respectively. The oil showed promising activity against staph aureus, while showed weak activity against (Hela and 3T3) cell lines. The crude extract / fractions of R. nervosus (leaves) showed significant antioxidant activity at dose (100 and 80) μg/mL. Futhermore the crude showed significant activity against (MCF-7 and MDA-MB-231) cell lines with IC50 (20.5138 ± 0.933 and 25.1728 ± 0.9176) μg/mL respectively, and chloroform fraction showed good activity against (MCF-7 and MDA-MB-231) cell lines with IC50 (31.154 ± 0.965 and 42.269 ± 2.1045) μg/mL. 相似文献
314.
Sadiq‐ur‐Rehman Saqib Ali M. Mazhar Amin Badshah Masood Parvez 《Heteroatom Chemistry》2006,17(5):420-432
The complexes Me2SnL2 ( I ), Me3SnL ( II ), Et2SnL2 ( III ), n‐Bu2SnL2 ( IV ), n‐Bu3SnL ( V ), n‐Oct2SnL2 ( VI ), Bz2SnL2 ( VII ), and Ph3SnL ( VIII ), where “L” is ( E )‐3‐(3‐fluorophenyl)‐2‐phenyl‐2‐propenoate, have been prepared and structurally characterized by means of elemental analysis, infrared, mass, and multinuclear (1H, 13C, 119Sn) NMR spectral techniques. The spectroscopic results showed that the geometry around the Sn atom in triorganotin(IV) derivatives is four‐coordinated in noncoordinating solvent and behaves as five‐coordinated linear polymers with bridging carboxylate groups or five‐coordinated monomers, both acquiring trans‐R3SnO2 geometry for Sn in the solid state. While all the diorganotin(IV) derivatives may acquire trigonal bipyramidal structures in solution due to collapse of the Sn←OCO interaction and octahedral geometries in the solid state, which have been confirmed by the X‐ray crystallographic data of the compound III . The crystal structure of Et2SnL2 ( III ) has been determined by X‐ray crystallography and is found skew‐trapezoidal bipyramidal, which substantiates that the ligand acts as an anisobidentate chelating agent, thus rendering the Sn atom six coordinated. The crystal is monoclinic with space group C21/n. All the investigated compounds have also been screened for biocidal and cytotoxicity data. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:420–432, 2006; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20243 相似文献
315.
316.
After reporting the excellent etching properties of molten Ba(OH)2 8H2O as an etchant, we now report some more new and efficient etchants for CR-39 detector. CR-39 detectors were irradiated with fission fragments and alpha particles with a thin 252Cf source. The irradiated detectors were etched in a number of our newly introduced etching solutions as well as in conventionally used 6 M NaOH at 70 degrees C. The newly prepared etching solutions included NaOH/ethanol and NaOH/1-propanol. Processing conditions were optimized for these etchants. From fission and alpha track diameters, bulk etching velocity (VB), track etching velocity (VT), etching efficiency (eta) and their activation energies were determined and compared with that obtained for 6M NaOH at 70 degrees C. 相似文献
317.
Fakhar-e-Alam M. Firdous S. Atif M. Khan Y. Zaidi S. S. Z. Suleman R. Rehman A. Khan R. U. Nawaz M. Ikram M. 《Laser Physics》2011,21(12):2156-2164
Drug delivery into the malignant cell is a basic requirement for effectiveness of photosensitizing systems for photodynamic
therapy (PDT). For anticancer tumoricidal drugs, e.g., 5-aminolevulinic acid (ALA), zinc oxide (ZnO) nanoparticles (NPs) are
used as efficient intracellular photosensitizer carriers. Apoptotic effect of tumoricidal drugs (ALA and Photofrin cells in
the presence and absence of ZnO NPs using confocal microscopy as well as Neutral Red Assay (NRA). In dark, ZnO NPs conjugated
with ALA or Photofrinhas been found to have a remarkable fluorescence in Hepatucellular carcinoma (HepG2) cells. This fact
illustrates the great potential of ZnO NPs as biomarker in relevant clinical and biomedical applications. 相似文献
318.
Present study evaluates the effects of photodynamic therapy (PDT) with aminolevulinic acid (5-ALA) as photo sensitizer using Human embryonic kidney (HEK293T) cell line as an experimental model. Porphyrins derivatives are used as active cytotoxic antitumor agents in PDT. Above mentioned cell line were irradiated with red light (a diode laser, λ = 635 nm) at different doses (0–160 J/cm2) of light. The influence/effectiveness of incubation time, various concentrations of aminolevulinic acid (5-ALA) and light doses on the cellular viability was studied. HEK293T cells were deliberated by exposing the ALA-PpIX (0–1000 μg/ml) of concentrations. The optimal uptakes of photosensitizer (PS) in cell lines were investigated by means of spectro photo metric measurements. Cells viability was determined by means of neutral red assay (NRA). It was observed that alone, neither photosensitizer nor light dose have significant effect on cells viability, but optimal concentration of PS along with suitable dose of light exhibit effective impact on the viability of cell. Our results showed that light doses of 40 J/cm2 demonstrates effective PDT outcome for HEK293T cell line when incubated with 400 μg/ml, with wrapping up view that HEK293T cell line is very sensitive to ALA-mediated PDT as compared to cell line published in our data. At the end results has been verified by using reactive oxygen species (ROS) measure test. 相似文献
319.
Javid Hussain Najeeb Ur Rehman Hidayat Hussain Liaqat Ali Ahmed Al‐Harrasi Viqar Uddin Ahmad 《Helvetica chimica acta》2011,94(11):2106-2110
The structure elucidation of two new phthalate derivatives named nepethalates A ( 1 ) and B ( 2 ) is reported. Both of these secondary metabolites were isolated from the MeOH extract of Nepeta clarkei. HR‐EI‐MS, IR and UV absorption spectrometry, and NMR experiments including COSY, HMQC, and HMBC were used for the determination of the structures and complete 1H‐ and 13C‐NMR assignments. 相似文献
320.
Unusual Structural Features in the Lysozyme Derivative of the Tetrakis(acetato)chloridodiruthenium(II,III) Complex
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Prof. Luigi Messori Tiziano Marzo Rute Nazaré Fernandes Sanches Hanif‐Ur‐Rehman Prof. Denise de Oliveira Silva Dr. Antonello Merlino 《Angewandte Chemie (International ed. in English)》2014,53(24):6172-6175
The reaction between the paddle‐wheel tetrakis(acetato)chloridodiruthenium(II,III) complex, [Ru2(μ‐O2CCH3)4Cl] and hen egg‐white lysozyme (HEWL) was investigated through ESI‐MS and UV/Vis spectroscopy and the formation of a stable metal–protein adduct was unambiguously demonstrated. Remarkably, the diruthenium core is conserved in the adduct while two of the four acetate ligands are released. The crystal structure of this diruthenium–protein derivative was subsequently solved through X‐ray diffraction analysis to 2.1 Å resolution. The structural data are in agreement with the solution results. It was found that HEWL binds two diruthenium moieties, at Asp101 and Asp119, respectively, with the concomitant release of two acetate ligands from each diruthenium center. 相似文献