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21.
Yu KO Jung J Ramzi AB Kim SW Park C Han SO 《Applied biochemistry and biotechnology》2012,166(4):856-865
The conversion of low-priced glycerol to higher value products has been proposed as a way to improve the economic viability
of the biofuels industry. In a previous study, the conversion of glycerol to ethanol in a metabolically engineered strain
of Saccharomyces cerevisiae was accomplished by minimizing the synthesis of glycerol, the main by-product in ethanol fermentation processing. To further
improve ethanol production, overexpression of the native genes involved in conversion of pyruvate to ethanol in S. cerevisiae was successfully accomplished. The overexpression of an alcohol dehydrogenase (adh1) and a pyruvate decarboxylase (pdc1) caused an increase in growth rate and glycerol consumption under fermentative conditions, which led to a slight increase
of the final ethanol yield. The overall expression of the adh1 and pdc1 genes in the modified strains, combined with the lack of the fps1 and gpd2 genes, resulted in a 1.4-fold increase (about 5.4 g/L ethanol produced) in fps1Δgpd2Δ (pGcyaDak, pGupCas) (about 4.0 g/L ethanol produced). In summary, it is possible to improve the ethanol yield by overexpression of the genes
involved in the conversion of pyruvate to ethanol in engineered S. cerevisiae using glycerol as substrate. 相似文献
22.
Synergistic Effect of Bioactive Monoterpenes against the Mosquito,Culex pipiens (Diptera: Culicidae)
Amal Ramzi Abdelhakim El Ouali Lalami Saoussan Annemer Yassine Ez zoubi Amine Assouguem Mikhlid H. Almutairi Mohamed Kamel Ilaria Peluso Sezai Ercisli Abdellah Farah 《Molecules (Basel, Switzerland)》2022,27(13)
Mosquitoes represent one of the most important vectors and are responsible for the transmission of many arboviruses that affect human and animal health. The chemical method using synthetic insecticides disturbs the environmental system and promotes the appearance of resistant insect species. Therefore, this study investigated the insecticidal effect of some binary monoterpene combinations (1,8 cineole + α-pinene and carvone + R (+)-pulegone) using a mixture design approach. The fumigant toxicity was evaluated against Culex pipiens female adults using glass jars. The results show that the toxicity varies according to the proportions of each compound. Indeed, Mixture 1 (1,8-cineole + α-pinene) displayed a strong toxic effect (51.00 ± 0.86% after 24 h and 100.00 ± 0.70% after 48 h) when the pure compounds were tested at 0.25/0.75 proportions of 1,8-cineole and α-pinene, respectively. Nevertheless, the equal proportion (0.5/0.5) of carvone and R (+)-pulegone in Mixture 2 exhibited a toxic effect of 54.35 ± 0.75% after 24 h and 89.96 ± 0.14% after 48 h, respectively. For Mixture 1, the maximum area of mortality that the proposed model indicated was obtained between 0/1 and 0.25/0.75, while the maximum area of mortality in the case of Mixture 2 was obtained between 0.25/0.75 and 0.75/0.25. Moreover, the maximum possible values of mortality that could be achieved by the validated model were found to be 51.44% (after 24 h) and 100.24% (after 48 h) for Mixture 1 and 54.67% (after 24 h) and 89.99% (after 48 h) for Mixture 2. It can be said that all purev molecules tested through the binary mixtures acted together, which enhanced the insecticide’s effectiveness. These findings are very promising, as the chemical insecticide (deltamethrin) killed only 19.29 ± 0.01% and 34.05 ± 1.01% of the female adults after 24 h and 48 h, respectively. Thus, the findings of our research could help with the development of botanical insecticides that might contribute to management programs for controlling vectors of important diseases. 相似文献
23.
Patricia Gizecki Ramzi Ait Youcef Cline Poulard Robert Dhal Gilles Dujardin 《Tetrahedron letters》2004,45(52):9589-9592
Under Lewis acid conditions, reaction of N-Boc, O-Me acetals with the (R)-(+)-O-vinyl-pantolactone does not lead to the expected dihydrooxazine, but to the corresponding tetrahydrooxazinone, as a result of the loss of the t-Bu group. A diastereoselective and asymmetrical way to these new heterocyclic compounds is described, together with the first evidence of their ability to undergo N-acylation. 相似文献
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We re-prove various uniqueness theorems for the Navier–Stokes equations, stating the assumptions in terms of multipliers between Sobolev spaces instead of Lebesgue or Lorentz spaces. 相似文献
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Suppliers network in the global context under price discounts and uncertain fluctuations of currency exchange rates have become critical in today’s world economy. We study the problem of suppliers’ selection in the presence of uncertain fluctuations of currency exchange rates and price discounts. We specifically consider a buyer with multiple sites sourcing a product from heterogeneous suppliers and address both the supplier selection and purchased quantity decision. Suppliers are located worldwide and pricing is offered in suppliers’ local currencies. Exchange rates from the local currencies of suppliers to the standard currency of the buyer are subject to uncertain fluctuations overtime. In addition, suppliers offer discounts as a function of the total quantity bought by the different customer’ sites over the time horizon irrespective of the quantity purchased by each site. 相似文献
29.
Yufeng Jiang Ramzi Chakroun Peiyang Gu Andr H. Grschel Thomas P. Russell 《Angewandte Chemie (International ed. in English)》2020,59(31):12751-12755
Soft polymeric Janus nanoparticles (JNPs), made from polystyrene‐b‐poly(butadiene)‐b‐poly(methylmethacrylate), PS‐PB‐PMMA, triblock terpolymers, assemble into a monolayer at the water–oil interface to reduce interfacial tension. The extent to which the polymer chains can deform influences the packing density of the JNPs at the interface. The longer the polymer chains are relative to the core, the softer are the JNPs, resulting in a JNPs assembly with a lower initial lateral packing density. The interfacial activity of JNPs can be further tuned by complexation of the PMMA chains with lithium ions that are introduced into the water phase. This work provides a fundamental understanding of soft JNPs packing at the water–oil interface and provides a strategy to tailor the areal density of soft JNPs at liquid–liquid interface, enabling the design of smart responsive structured‐liquid systems. 相似文献
30.
Ramzi Ksouri 《Applied Categorical Structures》2016,24(3):283-314
We define the notion of duality categories as generalization of duality groups. Two examples are treated. The first is the Serre duality in the categories of strict polynomial functors. The second concerns finite complexes. We show in particular that finite Tits buildings are duality categories. 相似文献