2, 3-Diaryl-5-ethylsulfanylmethyltetrahydrofurans as a new class of COX-2 inhibitors and cytotoxic agents

2,3-Diaryl-5-ethylsulfanylmethyltetrahydrofuran-3-ols were designed and synthesized by the allylations of benzoins followed by iodocyclization and nucleophilic replacement reactions with ethanthiol. These molecules exhibit IC(50) for COX-2 at <10 nM concentration and exhibit average GI(50) over all the 59 human tumor cell lines at microM concentration.     

Self-assembly and potassium ion triggered disruption of peptide-based soft structures

This report describes formation of soft vesicular structures by a tetrapeptide and its disruption triggered by potassium ions.     

Volumetric and Acoustic Behavior of PEG-200 and PEG-600 in Aqueous D-Mannitol solutions at Different Temperatures

Journal of Solution Chemistry - The interlinkage among the molecules of polyethylene glycols (PEG-200 and PEG-600) in aqueous D-Mannitol solutions are analyzed in the current investigation from the...     

Synthesis of Copper Metal Organic Framework Based on Schiff Base Tricarboxylate Ligand for Highly Selective and Sensitive Detection of 2,4,6-Trinitrophenol in Aqueous Medium

Journal of Fluorescence - By using Schiff base tricarboxylate ligand 5-(4-carboxybenzylideneamino)isophthalic acid (H3CIP), a new imine functionalized copper metal organic framework (MOF) has been...     

Chemoselective Oxidation of Benzylic Alcohols with Solid Supported CrO3/TBHP Under Microwave Irradiation

The efficient use of microwave energy coupled with dry media technique for the oxidation of benzylic alcohols using catalytic CrO₃ and TBHP has been effectively projected     

Study of the amplification characteristics of a coaxial EDF with varying coupling conditions

A coaxial erbium doped fiber (EDF) designed to show inherent gain flattening for one of its propagating modes in general supports two or more modes with different gains. In this paper, we show that when such an amplifying coaxial EDF is spliced to a single mode transmission fiber carrying the signal, in general, more than one mode is excited each with its excitation coefficient strongly dependent on wavelength. Due to the interference between these modes, the amplified output coupled to an output single core transmission fiber can be a very sensitive function of the coaxial EDF length, especially around the phase matching wavelength (PMW), and does not show inherent gain flattening. However, due to interference between the two modes, the coaxial fiber acts as a band reject filter at the phase matching wavelength with attenuation and bandwidth depending on fiber parameters. This property can be employed for inherent gain flattening when both modes are excited.     

Study of enhanced red emission from Sm(Sal)3Phen ternary complexes in Poly Vinyl Alcohol film

In the present work, dinuclear complexes of salicylic acid (Sal) and 1,10-phenanthroline (Phen) were synthesized with different concentrations of Samarium ion (Sm³⁺) in Poly Vinyl Alcohol (PVA) polymer films and their structural and spectroscopic properties were investigated. Judd-Ofelt theory has been employed to estimate the several radiative parameters for SmCl₃ and Sm(Sal)₃Phen complex in PVA polymer film which are in fairly agreement between the experimental and the theoretical values supporting the J-O theory. Photoluminescence properties of the complex have been studied on 355 nm and 400 nm excitations in steady state as well as in time domain. On the basis of the UV-Vis absorption, FT-IR absorption, excitation, emission spectra and decay curves, spectroscopic properties of these films were studied and the photophysics involved was explained in terms of energy transfer and the RE encapsulation effect.     

Simple Strategy of Repeated Batch Cultivation for Enhanced Production of 1,3-Propanediol Using Clostridium diolis

Repeated batch cultivation (empty-and-fill protocol) using obligate anaerobe Clostridium diolis was attempted in the present study to improve the production of 1,3-propanediol (1,3-PD). In repeated batch operation, 20?% (v/v) culture broth was removed from the bioreactor and supplemented with an equal volume of fresh nutrient medium when the residual glycerol concentration in the bioreactor decreased below 15?g/L. Four cycles of culture broth withdrawal and subsequent replacement resulted in achieving a 1,3-PD concentration of 67.8?g/L with a productivity of 1.04?g/L/h at the end of 65?h. This represented a 1,3-PD concentration and productivity enhancement by 2.6-fold and 1.5-fold, respectively, as compared to batch 1,3-PD fermentation. This is the first report on the use of repeated batch mode of bioreactor operation for enhanced 1,3-PD production.     

Structure–property correlations in lead silicate glasses and crystalline phases

Lead silicate glasses containing 40–65?mol% of PbO were prepared at two melt-quenching rates and characterized by X-ray diffraction, UV-Visible absorption spectroscopy, density, microhardness, thermo-mechanical analysis, differential scanning calorimetry and Raman scattering studies. On increasing the PbO concentration, density increases, glass transition temperature decreases and the optical absorption edge shifts towards longer wavelength. An intense optical absorption band was observed just below the absorption edge in glasses with 55?mol% and higher concentration of PbO. Dilatometric measurements show an unusual property that glasses do not show any abrupt increase in volume near the glass transition temperature but transform directly into the liquid state. Raman spectroscopy confirmed that the concentration of SiO₄ tetrahedra containing one or more NBOs increase with PbO mol%. Devitrification studies on lead silicate glasses found that samples with 40–45?mol% of PbO do not crystallize, whereas samples with higher PbO concentration produce multiple crystalline phases like PbSiO₃, Pb₃₃Si₂₄O₈₁, Pb₂SiO₄ and Pb₃Si₂O₇ on heat treatment.