Ruthenium(III) complexes of amine-bis(phenolate) ligands as catalysts for transfer hydrogenation of ketones

Twelve ruthenium(III) complexes bearing amine-bis(phenolate) tripodal ligands of general formula [Ru(L¹–L³)(X)(EPh₃)₂] (where L¹–L³ are dianionic tridentate chelator) have been synthesized by the reaction of ruthenium(III) precursors [RuX₃(EPh₃)₃] (where E = P, X = Cl; E = As, X = Cl or Br) and [RuBr₃(PPh₃)₂(CH₃OH)] with the tripodal tridentate ligands H₂L¹, H₂L² and H₂L³ in benzene in 1:1 molar ratio. The newly synthesized complexes have been characterized by analytical (elemental and magnetic susceptibility) and spectral methods. The complexes are one electron paramagnetic (low-spin, d⁵) in nature. The EPR spectra of the powdered samples at RT and the liquid samples at LNT shows the presence of three different ‘g’ values (g_x ≠ g_y ≠ g_z) indicate a rhombic distortion around the ruthenium ion. The redox potentials indicate that all the complexes undergo one electron transfer process. The catalytic activity of one of the complexes [Ru(pcr-chx)Br(AsPh₃)₂] was examined in the transfer hydrogenation of ketones and was found to be efficient with conversion up to 99% in the presence of isopropanol/KOH.     

Simple method for the determination of rosiglitazone in human plasma using a commercially available internal standard

To the best of our knowledge, bioanalytical methods to determine rosiglitazone in human plasma reported in literature use internal standards that are not commercially available. Our purpose was to develop a simple method for the determination of rosiglitazone in plasma employing a commercially available internal standard (IS). After the addition of celecoxib (IS), plasma (0.25 mL) samples were extracted into ethyl acetate. The residue after evaporation of the organic layer was dissolved in 750 microL of mobile phase and 50 microL was injected on to HPLC. The separation was achieved using a Hichrom KR 100, 250 x 4.6 mm C(18) with a mobile phase composition potassium dihydrogen phosphate buffer (0.01 m, pH 6.5):acetonitrile:methanol (40:50:10, v/v/v). The flow-rate of the mobile phase was set at 1 mL/min. The column eluate was monitored by fluorescence detector set at an excitation wavelength of 247 nm and emission wavelength of 367 nm. Linear relationships (r(2) > 0.99) were observed between the peak area ratio rosiglitazone to IS vs rosiglitazone concentrations across the concentration range 5-1000 ng/mL. The intra-run precision (%RSD) and accuracy (%Dev) in the measurement of rosiglitazone were <+/-10.69 and <-12.35%, respectively across the QC levels (50-1000 ng/mL). The extraction efficiency was >80% for both rosiglitazone and IS from human plasma. The lower limit of quantitation of the assay was 5 ng/mL. In summary, the methodology for rosiglitazone measurement in plasma was simple, sensitive and employed a commercially available IS.     

Ejection of massive black holes from galaxies

Gravitational recoil of a gigantic black hole (M∼10^8–9 M_⊙) formed in the nonspherical collapse of the nuclear part of a typical galaxy can take place with an appreciable speed as a consequence of the anisotropic emission of gravitational radiation. Accretion of gaseous matter during its flight through the galaxy results in the formation of a glowing shock front. The accompanying stellar captures can lead to the formation of an accretion disk-star system about the hole. Consequently, the hole can become “luminous” enough to be observable after it emerges out of the galaxy. The phenomenon seems to have an importance in relation to the observations of quasar-galaxy association in a number of cases.     

Estimation of coefficient of variation in a weighted inverse Gaussian model

The coefficient of variation is an important parameter in many physical, biological and medical sciences. In this paper we study the estimation of the square of the coefficient of variation in a weighted inverse Gaussian model which is a mixture of the inverse Gaussian and the length biased inverse Gaussian distribution. This represents a rich family of distributions for different values of the mixing parameter and can be used for modelling various life testing situations. The maximum likelihood as well as the Bayes estimates of the parameters are obtained. These estimates are used to derive the estimates of the square of the coefficient of variation of the model under study. Several important data sets are analysed to illustrate the results. © 1996 John Wiley & Sons, Ltd.     

Magnetic and Raman scattering studies of Co-doped ZnO thin films grown by pulsed laser deposition

Phase pure Zn_1?x Co _x O thin films grown by pulsed laser deposition have transmittance greater than 75 % in the visible region. Raman studies confirm the crystalline nature of Zn_1?x Co _x O thin films. Zn_0.95Co_0.05O thin films show room temperature ferromagnetism with saturation magnetization of 0.4μ _B /Co atom. The possible origin of paramagnetism at higher Co doping concentrations can be attributed to the increased nearest-neighbor antiferromagnetic interactions between Co²⁺ ions in ZnO matrix. XPS confirms the substitution of Co²⁺ ions into the ZnO host lattice.     

On the minimum degree,edge-connectivity and connectivity of power graphs of finite groups

In this paper, the minimum degree of power graphs of certain cyclic groups, abelian p-groups, dihedral groups and dicyclic groups are obtained. It is ascertained that the edge-connectivity and minimum degree of power graphs are equal, and consequently, the minimum disconnecting sets of power graphs of the aforementioned groups are determined. In order to investigate the equality of connectivity and minimum degree of power graphs, certain necessary conditions for finite groups and a necessary and su?cient condition for finite cyclic groups are obtained. Moreover, the equality is discussed for the power graphs of abelian p-groups, dihedral groups and dicyclic groups.     

A relativistic core-envelope model on pseudospheroidal space-time

A core-envelope model for superdense matter distribution with the feature- core consisting of anisotropic fluid distribution and envelope with isotropic fluid distribution is reported on the background of pseudospheroidal space-time. The physical plausibility of the model is examined analytically and numerically.