Novel bioconjugates of aminolevulinic acid with vitamins

5-Aminolevulinic acid (ALA) and derivatives thereof have been successfully used in photodynamic cancer therapy (PDT). The synthesis of novel bioconjugates combining ALA with two lipophilic and one hydrophilic vitamins is reported. The new bioconjugates allow studying the potential synergies between the two components in PDT. The synthetic methodology is robust giving the bioconjugates in good to satisfactory yield.     

Coulomb interactions and nanoscale electronic inhomogeneities in manganites

We study electronic inhomogeneities in manganites using simulations on a microscopic model with Coulomb interactions amongst two electronic fluids-one localized (polaronic), the other extended-and dopant ions. The long range Coulomb interactions frustrate phase separation induced by the large on site repulsion between the fluids. A single phase ensues which is inhomogeneous at a nanoscale, but homogeneous on mesoscales, with many features that agree with experiments. This, we argue, is the origin of nanoscale inhomogeneities in manganites, rather than phase competition or disorder effects.     

Steam-reforming of ethanol for hydrogen production

Production of hydrogen by steam-reforming of ethanol has been performed using different catalytic systems. The present review focuses on various catalyst systems used for this purpose. The activity of catalysts depends on several factors such as the nature of the active metal catalyst and the catalyst support, the precursor used, the method adopted for catalyst preparation, and the presence of promoters as well as reaction conditions like the water-to-ethanol molar ratio, temperature, and space velocity. Among the active metals used to date for hydrogen production from ethanol, promoted-Ni is found to be a suitable choice in terms of the activity of the resulting catalyst. Cu is the most commonly used promoter with nickel-based catalysts to overcome the inactivity of nickel in the water-gas shift reaction. γ-Al₂O₃ support has been preferred by many researchers because of its ability to withstand reaction conditions. However, γ-Al₂O₃, being acidic, possesses the disadvantage of favouring ethanol dehydration to ethylene which is considered to be a source of carbon deposit found on the catalyst. To overcome this difficulty and to obtain the long-term catalyst stability, basic oxide supports such as CeO₂, MgO, La₂O₃, etc. are mixed with alumina which neutralises the acidic sites. Most of the catalysts which can provide higher ethanol conversion and hydrogen selectivity were prepared by a combination of impregnation method and sol-gel method. High temperature and high water-to-ethanol molar ratio are two important factors in increasing the ethanol conversion and hydrogen selectivity, whereas an increase in pressure can adversely affect hydrogen production.     

Functional and preliminary characterisation of hydrocolloid from tamarillo (Solanum betaceum Cav.) puree

Hydrocolloid from tamarillo (Solanum betaceum Cav.) puree was extracted using water and characterised for the first time. Proximate compositions of the extracted hydrocolloid were also determined. Functional characteristics such as water-holding capacity, oil-holding capacity, emulsifying activity, emulsion stability, foaming capacity and stability of the hydrocolloid were evaluated in comparison to that of commercial hydrocolloids. Its functional groups and degree of esterification were determined using Fourier Transform Infrared (FT-IR) spectroscopy. Monosaccharide profiling was done using reverse-phase high pressure liquid chromatography (RP-HPLC). Screening of various fruits for high hydrocolloid yield after water extraction resulted in tamarillo giving the highest yield. The yield on dry weight basis was 8.30%. The hydrocolloid constituted of 0.83% starch, 21.18% protein and 66.48% dietary fibre with 49.47% degree of esterification and the monosaccharides identified were mannose, ribose, rhamnose, galacturonic acid, glucose, galactose, xylose and arabinose. Higher oil-holding capacity, emulsifying activity and emulsion stability compared to commercial hydrocolloids propose its possible application as a food emulsifier and bile acid binder. Foaming capacity of 32.19% and good foam stabilisation (79.36% of initial foam volume after 2 h of foam formation) suggest its promising application in frothy beverages and other foam based food products. These findings suggest that water-extracted tamarillo hydrocolloid can be utilised as an alternative to low methoxyl pectin.     

Strongly correlated superconductivity in Rh17S15

In this Letter, we report resistivity, susceptibility, heat capacity, and upper critical field studies on a polycrystalline Rh17S15 sample which exhibits superconductivity below 5.4 K. Detailed studies suggest that the superconductivity in this compound arises from strongly correlated charge carriers presumably due to the high density of states of Rh d bands at the Fermi level. Moreover, the Hall coefficient shows a sign change and increases at low temperature before the sample becomes a superconductor below 5.4 K.     

Queue length and occupancy in discrete-time cyclic networks with several types of nodes

For a discrete-time, closed, cyclic queueing network, where the nodes have independent, geometric service times, the equilibrium rate of local progress is determined. Faster nodes are shown to have a capacity depending only on the service probabilities. A family of such networks, each with the same number of types of nodes, is analyzed. If the number of nodes approaches infinity, and if the ratio of jobs to nodes has a positive limit and each node type has an asymptotic density, then for a given node type, the limits of the proportion of occupied nodes and the expected queue length are calculated. These values depend on the service parameter and on the asymptotic rate of local progress. The faster nodes can attain their capacity only when the limiting density of nodes of slowest type is zero. This revised version was published online in June 2006 with corrections to the Cover Date.     

Wind dependence of ambient noise in shallow water of Bay of Bengal

This work reports on investigations into the wind dependence of ambient noise in the Bay of Bengal. Ambient noise measurements were made in the shallow water of Bay of Bengal using a portable broadband, high frequency data acquisition system together with a sensitive hydrophone suspended from the measuring platform at a depth of 5 m from the surface where the ocean depth was 25 m. Periodic measurements were carried out for one year corresponding to a wind speed range between 2 m/s and 9 m/s during summer, monsoon and winter seasons. The proportionality of the noise level with wind speed for frequencies ranging from 500 Hz to 6 kHz for each season was studied. The analysis reveals that the correlation between the wind speed and the ambient noise spectrum level was higher at lower frequencies. The results of empirical fitting based on analysis were used for noise level prediction and the model predictions compare well with the measured noise level. Further it was observed that the wind generated noise level measured during summer was approximately 8 dB less than that in other seasons. On the other hand the proportionality between the noise level and the wind speed was less during winter.