A new class of sulfone linked bisheterocycles—pyrrolyl pyrazoles, bispyrazoles, and pyrazolyl isoxazoles—were prepared from 1‐aroyl‐2‐styrylsulfonylethenes, and the products were characterized by spectral parameters and elemental analyses. 相似文献
Rheological evidence is provided demonstrating that covalent grafting of monodisperse isotactic poly(l-leucine) branches onto linear hyaluronan (HA) polysaccharide chains yields comb-branched HA chains that self-assemble into long-lived physical networks in aqueous solutions driven by hydrophobic interactions between poly(l-leucine) chains. This is in stark contrast to native (unmodified) HA solutions which exhibit no tendency to form long-lived physical networks. 相似文献
This Article presents the results from studies related to the chemistry of tricationic superelectrophiles. A series of triaryl methanols were ionized in Br?nsted superacids, and the corresponding tricationic intermediates were formed. The trications are found to participate in two types of reactions; both are characteristic of highly charged organic cations. One set of reactions occurs through charge migration. A second set of reactions occurs through deprotonation of an unusually acidic site on the tricationic species. One of the tricationic intermediates has been directly observed by low temperature NMR spectroscopy. These highly charged ions and their reactions have also been studied using density functional theory calculations. As a result of charge migration, electron density at a carbocation site is found to increase with progression from monocationic to pentacationic structures. 相似文献
We report the synthesis of lead piperidine and lead tetrahydroquinoline dithiocarbamate (DTC) complexes and their use as single source precursors for the preparation of anisotropic PbS nanoparticles. The complexes were thermolysed in coordinating solvents such hexadecylamime (HDA), tri-n-octylphosphine oxide (TOPO), oleylamine (OA) and decylamine (DA) at various reaction temperatures. The variation of the reaction conditions and precursors produced PbS particles with shapes ranging from spheres to cubes and rods. The size of the particles is generally larger than those synthesized by conventional precursor routes. The electron microscopy and X-ray diffraction data confirm the particles to be very crystalline with the dominant cubic rock salt phase present in all samples. 相似文献
Brilliance of terbium : Heterodimeric conjugates of trimethoprim covalently linked to sensitized terbium chelates bind to Escherichia coli dihydrofolate reductase fusion proteins with nanomolar affinity (see picture). Terbium luminescence enables sensitive and time‐resolved detection of labeled proteins in vitro and on the surface of living mammalian cells.
The rectilinear shortest path problem can be stated as follows: given a set of m non-intersecting simple polygonal obstacles in the plane, find a shortest L1-metric (rectilinear) path from a point s to a point t that avoids all the obstacles. The path can touch an obstacle but does not cross it. This paper presents an algorithm with time complexity O(n+m(lgn)3/2), which is close to the known lower bound of Ω(n+mlgm) for finding such a path. Here, n is the number of vertices of all the obstacles together. 相似文献
In this paper, we consider the problem of computing the region visible to a query point located in a given polygonal domain. The polygonal domain is specified by a simple polygon with m holes and a total of n vertices. We provide two bounds on the complexity of this problem. One approach constructs a data structure with space complexity O(n2) in time O(n2lgn) and yields a query time of O((1+min(m,|V(q)|))lg2n+m+|V(q)|). Here, V(q) represents the set of vertices of the visibility polygon of a query point q, and |E| denotes the number of edges in the visibility graph. The other approach provides a data structure with space complexity O(min(|E|,mn)+n) in time O(T+|E|+nlgn) with the query time of O(|V(q)|lgn+m). Here, T is the time to triangulate the given polygonal region (which is O(n+mlg1+m) for a small positive constant >0). In both of these approaches, O(m) additive factor in the query time is eliminated with an additional O((min(|E|,mn))2) space and an additional O(m(min(|E|,mn))2) preprocessing time. 相似文献
Three/two-photon resonant multiphoton ionization (MPI) of the CH3I monomer has been studied in the gas phase at 532 and 355 nm using time-of-flight mass spectrometry. Under low laser intensity (approximately 10(9) W/cm2) the mass spectra showed peaks at m/z 15, 127 and 142, corresponding to [CH3]+, [I]+ and [CH3I]+ species, at both these wavelengths. The laser power dependence for [CH3I]+, [I]+ and [CH3]+ ions showed a three-photon dependence at 532 nm. For the same three ions, photoionization studies at 355 nm gave a power dependence of 2. Both these results suggest that a vibronic energy level at approximately 7 eV, lying in the Rydberg C state, acts as a resonant intermediate level in ionization of CH3I. In the case of 355 nm, with increasing intensity additional peaks at m/z 139 and 141 were observed which could be assigned to [CI]+ and [CH2I]+ fragments. In contrast, for high intensity radiation at 532 nm ( approximately 2 x 10(10) W/cm2), only the [CI]+ fragment was observed. At these wavelengths, fragment ions observed in mass spectra mainly arise from photodissociation of the parent ion. Experiments at another wavelength in the visible region (564.2 nm) confirmed the results obtained at 532 nm. In order to assess the role of the A state in these MPI experiments, additional experiments were performed at 266 and 282.1 nm, which access the A state directly via a one-photon transition, and showed absence of a surviving precursor ion. Reaction energies for various possible dissociation channels of CH3I/[CH3I]+/[CH2I]+ were calculated theoretically at the MP2 level using the GAMESS electronic structure program. 相似文献
A green and efficient synthetic protocol has been developed for the synthesis of a new series of substituted diethyl(((2-methoxy-5-(trifluoromethyl)phenyl)amino)(phenyl)methyl)phosphonates via a one-pot three-component reaction of 2-methoxy-5-trifluoromethyl aniline with various aromatic-substituted aldehydes and diethyl phosphite using meglumine sulfate as an eco-friendly catalyst at room temperature under solvent-free conditions. The merits of this method are high product yield, short reaction time, easy workup, and purification. All the synthesized compounds were evaluated for the antioxidant activity by DPPH, NO, and H2O2 methods using ascorbic acid as a standard. The compounds 4a and 4g showed the highest antioxidant activity than that of the standard ascorbic acid. 相似文献