Curcumin is the primary polyphenol in turmeric’s curcuminoid class. It has a wide range of therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic, hepatoprotective, antibacterial, and anticancer effects against various cancers, but has poor solubility and low bioavailability. Objective: To improve curcumin’s bioavailability, plasma concentration, and cellular permeability processes. The nanocurcumin approach over curcumin has been proven appropriate for encapsulating or loading curcumin (nanocurcumin) to increase its therapeutic potential. Conclusion: Though incorporating curcumin into nanocurcumin form may be a viable method for overcoming its intrinsic limitations, and there are reasonable concerns regarding its toxicological safety once it enters biological pathways. This review article mainly highlights the therapeutic benefits of nanocurcumin over curcumin. 相似文献
In the present frame of work, Macrophomina phaseolina is encapsulated in silica matrices at various concentrations by low temperature sol-gel technique using tetraethylorthosilicate
(TEOS) as precursor. The optical and photophysical properties of these samples have been studied by second harmonics of Nd:YAG
laser at 532 nm. UV-visible absorption spectra of samples have been recorded and it is found that the absorption increases
with increase in concentration of fungus. Further, a decrease in output transmission intensity of the laser has been observed
with increase in fungus concentration. The temporal response of these samples has also been examined. The results show that
the fungus concentration can be measured within ∼15–20 min. This method of optical sensing of fungus in test sample is faster
than other techniques, such as the conventional colorimetric method which takes about 1 h. 相似文献
We present an efficient implementation of volumetric anisotropic image diffusion filters on
modern programmable graphics processing units (GPUs), where the mathematics behind volumetric diffusion is effectively reduced to the diffusion in 2D images.
We hereby avoid the computational bottleneck of a time consuming eigenvalue decomposition in $\mathbb{R}^3$.
Instead, we use a projection of the Hessian matrix along the surface normal onto the tangent plane of
the local isodensity surface and solve for the remaining two tangent space eigenvectors.
We derive closed formulas to achieve this and prevent the GPU code from branching.
We show that our most complex volumetric anisotropic diffusion filters gain a speed up of more than 600 compared to a CPU solution. 相似文献
Nano-crystalline sulfated zirconia catalyst, prepared by two-step sol–gel method, has been studied for the solvent free self
condensation of acetophenone to dypnone. The influence of calcination temperature on the structural, textural and catalytic
activity of sulfated zirconia has been analyzed. The surface acidity along with the structural and textural features of the
catalyst influenced its activity. The conversion of acetophenone was found to be effected by the variation in the reaction
and calcination temperature, however, the dypnone selectivity was not affected much. The catalyst calcined at 650 °C, showed
maximum dypnone selectivity of 92% with 68.2% acetophenone conversion at 170 °C after 7 h. The catalyst was reused up to five
cycles with marginal decrease in acetophenone conversion, however, without losing its selectivity for dypnone. 相似文献
The catalytic activity of nano-crystalline sulfated zirconia catalyst, prepared by sol–gel method and characterized by various
analytical tools, was evaluated for the esterification of caprylic acid with different short chain alcohols. The lower concentration
of catalyst (0.5 wt%) exhibited 96–98% conversion of caprylic acid with methanol and 100% selectivity for methyl caprylate
at 60 °C. The conversion was decreased with increasing carbon chain of alcohols namely with ethanol, n-propanol and n-butanol at 60 °C but increased significantly (91–98%) at higher reaction temperature. The selectivity for respective alkyl
caprylate was observed to be 100% irrespective of the alcohol used. The activity of the catalyst was slightly decreased with
successive five reaction cycles due to the water formed during the reaction. 相似文献
Chiral dimeric Mn(III) salen complex with 1R, 2R-(?)-diaminocyclohexane collar was immobilized on short channel large pore sized silica through a long linker of {(CH2)3–NH–melamine–piperazine} to investigate its performance in enantioselective epoxidation of chromenes, indene, styrene and cis β-methyl styrene in the presence of pyridine N-oxide (PyNO) as an axial base using aqueous NaOCl as an oxidant at 0 °C. The immobilized catalyst system showed high turnover frequency (TOF) and enantioselectivity for the smaller and bulkier alkenes like styrene, indene, 2,2-dimethylchromene and 6-cyano-2,2-dimethylchromene (ee up to 98%). These results are the best reported for heterogeneous catalyst under biphasic reaction conditions and were comparable to the dimeric Mn(III) salen system under homogeneous condition. The performance of the immobilized catalyst was retained for six reuse experiments. This protocol was extended to the synthesis of an antihypertensive drug (S)-Levchromakalim (ee 98%) at 1 g level. 相似文献
The structural, electronic, elastic and bonding properties of four transition metal carbides, ScC, YC (group III), VC and NbC (group V), have been investigated systematically using the first principles density functional theory (DFT). The full potential linearized augmented plane wave (FP-LAPW) method with the generalized gradient approximation (GGA) for the exchange correlation has been used for the calculation of the total energy. The ground state properties, such as equilibrium lattice constant, bulk modulus, are computed and compared with theoretical and experimental data. The electronic and bonding patterns of the two groups of compounds have been analyzed quantitatively and compared with the available data. It is clear from band structures that all the four transition metal monocarbides are metallic in nature. Analysis of elastic constants reveals that the carbides of group III are ductile in nature while those of group V are brittle. 相似文献
Constabelian codes can be viewed as ideals in twisted group algebras over finite fields. In this paper we study decomposition of semisimple twisted group algebras of finite abelian groups and prove results regarding complete determination of a full set of primitive orthogonal idempotents in such algebras. We also explicitly determine complete sets of primitive orthogonal idempotents of twisted group algebras of finite cyclic and abelian p-groups. We also describe methods of determining complete set of primitive idempotents of abelian groups whose orders are divisible by more than one prime and give concrete (numerical) examples of minimal constabelian codes, illustrating the above mentioned results. 相似文献
The reaction of 2‐[bis(2‐methoxy‐phenyl)phosphanyl]‐4‐methyl‐benzenesulfonic acid (a) and 2‐[bis(2′,6′‐dimethoxybiphenyl‐2‐yl)phosphanyl]benzenesulfonic acid (b) with dimethyl(N,N,N′,N′‐tetramethylethylenediamine)‐palladium(II) (PdMe2(TMEDA)) leads to the formation of TMEDA bridged palladium based polymerization catalysts ( 1a and 1b ). Upon reaction with pyridine, two mononuclear catalysts are formed ( 2a and 2b ). These catalysts are able to homopolymerize ethylene and also copolymerize ethylene with acrylates or with norbornenes. With ligand b , high molecular weight polymers are formed in high yields, but higher comonomer incorporations are obtained with ligand a .