Ultra-broadband near-infrared pulse generation by noncollinear OPA with angular dispersion compensation

A scheme for the generation of an ultra-broadband, near-infrared beam from a Ti:sapphire source is proposed with the aim to serve as seed pulse of a petawatt-field synthesizer (Major et al. in Rev. Laser Eng. 37:431, 2009). The idler beam of a noncollinear optical parametric amplifier, pumped at the second harmonic of the Ti:sapphire output, displays the required bandwidth, albeit with an inherent angular chirp owing to the noncollinear geometry. We propose a scheme for the compensation of this angular dispersion which consists of a diffraction grating, a telescope and a deformable mirror. The suitability of this scheme is discussed quantitatively and preliminary experimental findings are shown.     

Molecular dynamics simulation of structural changes in metals under irradiation with high-energy heavy ions

To study the processes of irradiating metals with high-energy heavy ions, a thermal spike model is often used, i.e., a system of electron-gas thermal conductivity equations and a lattice. Upon the irradiation of materials with high-energy heavy ions, more than 90% of the energy is consumed in the excitation of the electronic subsystem of the irradiated material. Further, this energy is transferred to the lattice subsystem and there is high heating of the lattice in a small volume, which can cause melting (evaporation), resulting in a structural change (amorphization, formation of high pressure areas, tracks, etc.) in the irradiated material. This work is devoted to studying structural changes in the surface of nickel by irradiation with high-energy ions of uranium. The thermal spike model is used for the initial distribution of temperature conditions in the irradiated nickel, which imitates the action of radiation on a molecular-dynamic system. The further evolution of the system is studied by molecular dynamics. As part of this approach, the processes of structural changes on the surface of the irradiated target can be investigated in more detail.     

Higher-Order Interference in Extensions of Quantum Theory

Quantum interference, manifest in the two slit experiment, lies at the heart of several quantum computational speed-ups and provides a striking example of a quantum phenomenon with no classical counterpart. An intriguing feature of quantum interference arises in a variant of the standard two slit experiment, in which there are three, rather than two, slits. The interference pattern in this set-up can be written in terms of the two and one slit patterns obtained by blocking one, or more, of the slits. This is in stark contrast with the standard two slit experiment, where the interference pattern cannot be written as a sum of the one slit patterns. This was first noted by Rafael Sorkin, who raised the question of why quantum theory only exhibits irreducible interference in the two slit experiment. One approach to this problem is to compare the predictions of quantum theory to those of operationally-defined ‘foil’ theories, in the hope of determining whether theories that do exhibit higher-order interference suffer from pathological—or at least undesirable—features. In this paper two proposed extensions of quantum theory are considered: the theory of Density Cubes proposed by Daki?, Paterek and Brukner, which has been shown to exhibit irreducible interference in the three slit set-up, and the Quartic Quantum Theory of ?yczkowski. The theory of Density Cubes will be shown to provide an advantage over quantum theory in a certain computational task and to posses a well-defined mechanism which leads to the emergence of quantum theory—analogous to the emergence of classical physics from quantum theory via decoherence. Despite this, the axioms used to define Density Cubes will be shown to be insufficient to uniquely characterise the theory. In comparison, Quartic Quantum Theory is a well-defined theory and we demonstrate that it exhibits irreducible interference to all orders. This feature of ?yczkowski’s theory is argued not to be a genuine phenomenon, but to arise from an ambiguity in the current definition of higher-order interference in operationally-defined theories. Thus, to begin to understand why quantum theory is limited to a certain kind of interference, a new definition of higher-order interference is needed that is applicable to, and makes good operational sense in, arbitrary operationally-defined theories.     

Identification of potential trypanothione reductase inhibitors among commercially available $$\upbeta $$-carboline derivatives using chemical space,lead-like and drug-like filters,pharmacophore models and molecular docking

American trypanosomiasis or Chagas disease caused by the protozoan Trypanosoma cruzi (T. cruzi) is an important endemic trypanosomiasis in Central and South America. This disease was considered to be a priority in the global plan to combat neglected tropical diseases, 2008–2015, which indicates that there is an urgent need to develop more effective drugs. The development of new chemotherapeutic agents against Chagas disease can be related to an important biochemical feature of T. cruzi: its redox defense system. This system is based on trypanothione (\(N^{1}\),\(N^{8}\)-bis(glutathyonil)spermidine) and trypanothione reductase (TR), which are rather unique to trypanosomes and completely absent in mammalian cells. In this regard, tricyclic compounds have been studied extensively due to their ability to inhibit the T. cruzi TR. However, synthetic derivatives of natural products, such as \(\upbeta \)-carboline derivatives (\(\upbeta \)-CDs), as potential TR inhibitors, has received little attention. This study presents an analysis of the structural and physicochemical properties of commercially available \(\upbeta \)-CDs in relation to compounds tested against T. cruzi in previously reported enzymatic assays and shows that \(\upbeta \)-CDs cover chemical space that has not been considered for the design of TR inhibitors. Moreover, this study presents a ligand-based approach to discover potential TR inhibitors among commercially available \(\upbeta \)-CDs, which could lead to the generation of promising \(\upbeta \)-CD candidates.     

Temperature dependence of the lowest frequency <Emphasis Type="BoldItalic">E</Emphasis><Subscript><Emphasis Type="Bold">g</Emphasis></Subscript> Raman mode in laser-synthesized anatase TiO<Subscript>2</Subscript> nanopowder

Nanosized titanium dioxide (TiO₂) powder was prepared by a laser-induced pyrolysis. Specific surface area of the as-grown powder measured by BET method was 109 m²/g. The grain size (14.5 nm) estimated from these data coincides well with the crystallite size (12.3 nm) determined by XRD measurements. The average grain size (∼35 nm) obtained from the subsequent SEM measurements refers to considerable agglomeration of nanoparticles. Raman spectroscopy has been used to investigate the structural properties of TiO₂ nanopowder and its anatase structure is confirmed. The blueshift and broadening of the lowest frequency E_g Raman mode at temperature range ∼25–550 K have been analyzed using a phonon-confinement model. Dominant influence of the strong anharmonic effect at higher temperatures was demonstrated. PACS 81.07.Wx; 78.30.-j; 63.22.+m     

Electroweak boson detection in the ALICE muon spectrometer

The ALICE capabilities for W and Z detection at LHC are discussed. The contributions to single muon transverse momentum distribution are evaluated. The expected performance of the muon spectrometer for detecting W and Z bosons via their muonic decay is presented. Possible application for the study of in-medium effects in ultrarelativistic heavy ion collisions is discussed.     

Multiscaled polarization effects in <Emphasis Type="Italic">Suneve coronata</Emphasis> (Lepidoptera) and other insects: application to anti-counterfeiting of banknotes

The scales of many Lepidoptera and the elytra of quite a number of Coleoptera possess specialized micro- and nano-structures that produce special polarization effects. They are constituted by concave multilayered cavities. This leads to two different effects: (1) interferential non-polarized coloration by reflection near normal incidence in the middle of the cavities and (2) polarized interferential colouration at lower wavelength after double reflection near the Brewster incidence at the periphery of the cavities. The macroscopic appearance resembles the “pointillist effect” with one of the component polarized while the other one is not. The first one can be extinguished with linear polarizer so that the colour is modified. In most insects, the structure is locally symmetric; hence, no macroscopic effects can be seen. In certain species, this symmetry is partly broken, and a slight effect can be observed. In the wing dorsal surface of the fascinating neotropical butterflies genus Suneve, perpendicular structures of two different kinds in size polarize the reflected light. The larger one is constituted by the convex cover scales whose apex falls perpendicularly on the bases of the following scales, creating long polarized valley (50 μm width) transversally running across the wing. The smaller one is constituted by the ridges of the scales (2 μm apart) that polarize light in the perpendicular direction.Adapted multilayered structures can be deposited onto banknotes to create anti-counterfeiting patterns as a further development of protection and security. Different effects can be produced by the use of such structures. (1) Changes of luminosity: A specific pattern will be constituted by two different areas: one with horizontal concave multilayered structures, and the other one with vertical structures. Under unpolarized light, the reflected spectra of these different areas are identical and no pattern appears. Under polarized light, i.e., through a linear polarizer, one or the other area is partly extinguished, according to the orientation of the polarizer, and the pattern appears. (2) Changes in colours: a compound colour can be produced by the juxtaposition of planed and grooved surfaces. Due to the change of incidence of the incoming light, the colours of these two zones are different, but that produced by the first one is unpolarized while the second one is partly polarized and can be modified with a linear polarizer. PACS 42.25.Ja; 42.25.Hz; 42.66.Ne; 78.40.Me     

Revisiting Gouy phase

The aim of this paper is to highlight the added value of the generalized Gouy phase shift introduced by Siegman. Although suited for optical systems study, including those more complex than free space, we note that it did not meet the use that it deserves so far. The analysis of the whole of the ideas and analytical approaches associated to the important concept of the Gouy phase proves its effectiveness.

Usually, the resonance condition is systematically built on the basis of the equivalent empty cavity. Unfortunately, this approach does not cover some of the useful parameters of the real resonator. By means of the generalized Gouy phase and the self-consistent complex parameter q, we derive here a new approach for the calculation of the resonance condition for the real cavity. Moreover, the use of the generalized Gouy phase clearly simplifies the study of resonators, while making it possible to avoid the use of the Huygens’ Fresnel integral.