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61.
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A. P. W. Münch R. Th. Heukers H. A. J. Pieters und K. Penners 《Fresenius' Journal of Analytical Chemistry》1937,111(5-6):204
Ohne Zusammenfassung 相似文献
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Sigrid Pieters Wouter Saeys Tom Van den Kerkhof Mohammad Goodarzi Mario Hellings Thomas De Beer Yvan Vander Heyden 《Analytica chimica acta》2013
Owing to spectral variations from other sources than the component of interest, large investments in the NIR model development may be required to obtain satisfactory and robust prediction performance. To make the NIR model development for routine active pharmaceutical ingredient (API) prediction in tablets more cost-effective, alternative modelling strategies were proposed. They used a massive amount of prior spectral information on intra- and inter-batch variation and the pure component spectra to define a clutter, i.e., the detrimental spectral information. This was subsequently used for artificial data augmentation and/or orthogonal projections. The model performance improved statistically significantly, with a 34–40% reduction in RMSEP while needing fewer model latent variables, by applying the following procedure before PLS regression: (1) augmentation of the calibration spectra with the spectral shapes from the clutter, and (2) net analyte pre-processing (NAP). The improved prediction performance was not compromised when reducing the variability in the calibration set, making exhaustive calibration unnecessary. Strong water content variations in the tablets caused frequency shifts of the API absorption signals that could not be included in the clutter. Updating the model for this kind of variation demonstrated that the completeness of the clutter is critical for the performance of these models and that the model will only be more robust for spectral variation that is not co-linear with the one from the property of interest. 相似文献
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Transonic trailing-edge flow 总被引:1,自引:0,他引:1
Bodonyi RJ; Kluwick A 《The Quarterly Journal of Mechanics and Applied Mathematics》1998,51(2):297-310
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Susana A. Llivisaca-Contreras Jaime Naranjo-Morn Andrea Pino-Acosta Luc Pieters Wim Vanden Berghe Patricia Manzano Jeffrey Vargas-Prez Fabian Len-Tamariz Juan M. Cevallos-Cevallos 《Molecules (Basel, Switzerland)》2021,26(13)
COVID-19 is a pandemic disease caused by the SARS-CoV-2 virus, which is potentially fatal for vulnerable individuals. Disease management represents a challenge for many countries, given the shortage of medicines and hospital resources. The objective of this work was to review the medicinal plants, foods and natural products showing scientific evidence for host protection against various types of coronaviruses, with a focus on SARS-CoV-2. Natural products that mitigate the symptoms caused by various coronaviruses are also presented. Particular attention was placed on natural products that stabilize the Renin–Angiotensin–Aldosterone System (RAAS), which has been associated with the entry of the SARS-CoV-2 into human cells. 相似文献