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71.
The total synthesis of the 43 amino acid antibacterial peptide Microcin B17 (MccB17) is described. The natural product was synthesized via a convergent approach from a heterocycle-derived peptide and peptide thioester fragments prepared via Fmoc-strategy solid phase peptide synthesis (SPPS). Final assembly was achieved in an efficient manner using two Ag(I)-assisted peptide ligation reactions to afford MccB17 in excellent overall yield. 相似文献
72.
West NP Cergol KM Xue M Randall EJ Britton WJ Payne RJ 《Chemical communications (Cambridge, England)》2011,47(18):5166-5168
The first targeted inhibitors of an essential M. tuberculosis cell wall lipase, Rv3802c, are described. Lead compounds exhibited nanomolar inhibition of the enzyme, and encouraging antibacterial activity against M. tuberculosis in vitro, supporting Rv3802c as a novel TB drug target. 相似文献
73.
We examine differences between3H binding energies obtained by solving the Faddeev equations using standard partial-wave expansion procedures and results from solving the Schrödinger equation by means of the coupled-rearrangement-channel variational method. Variational bounds generated from Faddeev solutions for several contemporary, realistic potential models are presented as a function of the number of partial waves retained in the potential expansion. We demonstrate that the Faddeev wave function yields an optimal variational bound for the partial-wave truncated potential from which it is generated, but it does not yield optimal bounds for the full Hamiltonian or when the potential is partial-wave truncated at a different level. Finally, qualitative differences between3H solutions for static models such as the AV14 and RSC potentials and for momentum-dependent models such as the Nijmegen soft-core and Paris potentials are explored, and comparison is made with solutions for the RSC/TM two-body-force plus three-body-force model. 相似文献
74.
J. G. Parker E. E. M. Payne und Kommission der internationalen Vereinigung der Leder-Chemiker 《Fresenius' Journal of Analytical Chemistry》1906,45(12):773
Ohne Zusammenfassung 相似文献
75.
76.
H. L. Payne 《Fresenius' Journal of Analytical Chemistry》1894,33(1):457
Ohne Zusammenfassung 相似文献
77.
78.
The flow of a fluid through a porous medium is often modeled by the Brinkman or the Darcy system. In this paper we investigate
Saint-Venant type decay of solutions for both systems when the medium is confined to a semi-infinite cylinder and appropriate
homogeneous initial and boundary values are assumed.
Received: February 1, 1997 相似文献
79.
Stanley E. Payne 《Journal of Geometry》1988,33(1-2):113-128
A spread of PG(3,q), q an odd prime, recently constructed by R. Baker and G. Ebert, when generalized for q an odd prime power is isomorphic to a spread derived by J. A. Thas from a flock of a quadratic cone discovered by J. C. Fisher. The associated generalized quadrangle has an unusual colllneation. 相似文献
80.
J. L. Friar B. F. Gibson G. L. Payne 《Zeitschrift für Physik A Hadrons and Nuclei》1981,301(4):309-318
Three nucleon ground state wave functions are displayed graphically in configuration space. Both the Schrödinger functions and the Faddeev amplitudes from which they are constructed are plotted. It is demonstrated that for the case where the two-nucleon interaction contains strong repulsion at short distances, the Faddeev amplitude bears no resemblance to the Schrödinger function, and is not even positive definite. Furthermore, the Faddeev amplitude is a much smoother function of the three independent coordinate variables, and is therefore much easier to calculate. Certain intuitive features of the Schrödinger wave function are seen to be present. 相似文献