The Multifunctional Role of Herbal Products in the Management of Diabetes and Obesity: A Comprehensive Review

Obesity and diabetes are the most demanding health problems today, and their prevalence, as well as comorbidities, is on the rise all over the world. As time goes on, both are becoming big issues that have a big impact on people’s lives. Diabetes is a metabolic and endocrine illness set apart by hyperglycemia and glucose narrow-mindedness because of insulin opposition. Heftiness is a typical, complex, and developing overall wellbeing worry that has for quite some time been connected to significant medical issues in individuals, all things considered. Because of the wide variety and low adverse effects, herbal products are an important hotspot for drug development. Synthetic compounds are not structurally diverse and lack drug-likeness properties. Thus, it is basic to keep on exploring herbal products as possible wellsprings of novel drugs. We conducted this review of the literature by searching Scopus, Science Direct, Elsevier, PubMed, and Web of Science databases. From 1990 until October 2021, research reports, review articles, and original research articles in English are presented. It provides top to bottom data and an examination of plant-inferred compounds that might be utilized against heftiness or potentially hostile to diabetes treatments. Our expanded comprehension of the systems of activity of phytogenic compounds, as an extra examination, could prompt the advancement of remedial methodologies for metabolic diseases. In clinical trials, a huge number of these food kinds or restorative plants, as well as their bioactive compounds, have been shown to be beneficial in the treatment of obesity.     

Acetone Dimethyl Hydrazone: Useful Synthon+ for the Synthesis of Pheromones with Keto and Spiro Ketal Functions

The use of α-lithiated dimethyl hydrazones as an efficient enolate equivalent for the alkylation of ketones has been reported^1,2,3. Due to the ragioselectivity exhibited by acetone dimethyl hydrazone (1) towards the formation of bis alkylated products, we have used the easily avaiLable (1) as a convenient synthon for achieving a short and simple synthesis of pheromones, 1,7-dioxaspiro (5,5) undecane4 (2) and Z-6-Heneicosen-11-one (2). The key step in both the syntheses is the regioselective bis alkylation of (1) using butyl lithium as a base, as shown in Scheme I.     

High contrast electromagnetically induced transparency in a nitrogen filled Rb vapour cell

We observe the electromagnetically induced transparency (EIT) spectra inside a nitrogen filled Rb vapour cell (Rb-N₂) in a five-level Λ-type system of D₂ transition of Rb atom. The high contrast EIT resonance in buffer gas filled Rb cell is obtained under our experimental conditions. The effect of velocity changing coherence preserving collisions to obtain the contrast resonance in buffer gas cell has been discussed. We measured the dependence of EIT width and height on pump intensity and find that the EIT width (FWHM) and peak height have a linear dependence on pump intensity. Our experimental results show that the presence of N2 buffer gas reduces the power broadening of the observed resonances.     

Kaluza–Klein modes of bulk fields in a generalized Randall–Sundrum scenario

We consider a generalised two brane Randall–Sundrum model with non-zero cosmological constant on the visible TeV brane. Massive Kaluza–Klein modes for various bulk fields namely graviton, gauge field and antisymmetric second rank Kalb–Ramond field in a such generalized Randall–Sundrum scenario are determined. The masses for the Kaluza–Klein excitations of different bulk fields are found to depend on the brane cosmological constant indicating interesting consequences in warped brane particle phenomenology.     

A study of self-quenching of lyoluminescence yield from gamma-irradiated saccharides and amino acids

Tissue equivalent (TE) lyoluminescence (LL) dosimetry requires practical amount of phosphor for dissolution, typically 5-30 mg. Pronounced mass quenching effect has been observed even in the region of 5 mg, in the cases of LL of lactose-monohydrate, d-glucose, d-mannose, raffinose, sucrose and 1-glutamine. Ordinary concentration-quenching is non-existent but yield per mg falls rapidly with increasing mass of the phosphor. The curves have been fitted with a self-absorption type formula. A well-recognised dose effect is present in quenching curves. The role of free radicals at high radiation doses has been discussed in the contribution of dose effect in quenching.     

Effect of guest-host interaction on the dynamics of ethylene glycol in H-ZSM5 zeolite

Dynamics of ethylene glycol (EG) adsorbed in H-ZSM5 zeolite as studied using quasielastic neutron scattering (QENS) technique is reported here. Analysis of QENS data revealed that observed dynamics correspond to isotropic rotational motion of EG. Rotational diffusion coefficient of EG adsorbed in H-ZSM5 zeolite is found to be slower compared to bulk and comparable to that of benzene adsorbed in the same host. Positron Annihilation Spectroscopy (PAS) technique is used to understand the nature of guest-host interaction and the results of both QENS and PAS are found to be consistent with each other.     

Analysis of short-pulse laser photon transport through tissues for optical tomography

We describe a method for analyzing short-pulse laser propagation through tissues for the detection of tumors and inhomogeneities in tissues with the goal of developing a time-resolved optical tomography system. Traditional methods for analyzing photon transport in tissues usually involve the parabolic or diffusion approximation, which implies infinite speed of propagation of the optical signal. To overcome such limitations we calculate the transmitted and reflected intensity distributions, using the damped-wave hyperbolic P(1) and the discrete-ordinates methods, for a wide range of laser, tissue, and tumor parameters. The results are compared with the parabolic diffusion P(1) approximation.     

Dynamic multiscaling in turbulence

We give an overview of the progress that has been made in recent years in understanding dynamic multiscaling in homogeneous, isotropic turbulence and related problems. We emphasise the similarity of this problem with the dynamic scaling of time-dependent correlation functions in the vicinity of a critical point in, e.g., a spin system. The universality of dynamic-multiscaling exponents in fluid turbulence is explored by detailed simulations of the GOY shell model for fluid turbulence.     

Influence of magnetic quantization on the effective electron mass in Kane-type semiconductors

Summary We study the effective electron mass at the Fermi level in Kane-type semiconductors on the basis of fourth order in effective mass theory and taking into account the interactions of the conduction electrons, heavy holes, light holes and split-off holes, respectively. The results obtained are then compared to those derived on the basis of the well-known three-band Kane model. It is found, takingn-Hg_1−x Cd _x Te as an example, that the effective electron mass at the Fermi level in accordance with fourth-order model depends on the Fermi energy, magnetic quantum number and the electron spin respectively due to the influence of band nonparabolicity only. The dependence of effective mass on electron spin is due to spin-orbit splitting parameter of the valence band in three-band Kane model and the Fermi energy due to band nonparabolicity in two-band Kane model. The same mass exhibits an oscillatory magnetic-field dependence for all the band models as expected since the origin of oscillations in the effective mass in nonparabolic compounds is the same as that of the Shubnikov-de Hass oscillations. In addition, the corresponding results for parabolic energy bands have been obtained from the generalized expressions under certain limiting conditions.