Neural control of vocalization: Respiratory and emotional influences

Previous research has shown that a region of the midbrain, the periaqueductal gray matter (PAG), is critical for vocalization. In this review, we describe the results of previous investigations in which we sought to find out how PAG neurons integrate the activity and precise timing of respiratory, laryngeal, and oral muscle activity for natural-sounding vocalization using the technique of excitatory amino acid microinjections in cats. In these studies, all surgical procedures were carried out under deep anaesthesia. In the precollicular decerebrate cat two general types of vocalization, classified as voiced and unvoiced, could be evoked by exciting neurons in the lateral part of the intermediate part of the PAG. The patterns of evoked electromyographic activity were strikingly similar to previously reported patterns of human muscle activity. Coordinated patterns of activity were evoked with just-threshold excitation leading to the conclusion that patterned muscle activity corresponding to the major categories of voiced and voiceless sound production are represented in the PAG. In a parallel series of human and animal experiments, we also determined that the speech and vocalization respiratory patterns are integrated and coordinated with afferent signals related to lung volume. These data have led to the proposal of a new hypothesis for the neural control of vocalization: that the PAG is a crucial brain site for mammalian voice production, not only in the production of emotional or involuntary sounds, but also as a generator of specific respiratory and laryngeal motor patterns essential for human speech and song     

Tautomerism in acyl tetronic acids

The tautomeric structures of some acetyl tetronic acids are studied by NMR analysis.     

Oxalate films and red stains on Carrara marble

The analytical studies carried out during two different diagnostic surveys, respectively in 1983 and 2003, offered the opportunity to control decay phenomena development on stones facing Certosa of Pavia (Italy). Calcium oxalate films and red stains, present on Carrara marble surface, have been particularly focused; these are the only decay phenomena which apparently have remained unchanged during a period of twenty years. More sensitive and in-depth analytical studies (FTIR equipped with diamond cell, GC-MS, SEM-EDS and optical microscopy) achieved a better knowledge about their composition. Results allowed a critical evaluation of the role of oxalate films on the external marble surface and to suggest new hypotheses about the formation of red stains.     

Value Distribution of Interpolating Blaschke Products

A Blaschke product B with zero-sequence (a_n) is called almostinterpolating if the inequality lim inf_n(1 – |a_n|²)|B'(a_n)|     

A fluorescence polarisation molecular imprint sorbent assay for 2,4-D: a non-separation pseudo-immunoassay

The first pseudo-immunoassay which employs a molecularly imprinted receptor and a fluorescent probe, and quantifies the bound analyte directly using the fluorescence anisotropy of the polymer-probe-analyte suspension, is described.     

Reflections on Success and Retention in Urban Science Education: Voices of Five African‐American Science Teachers Who Stayed

This study highlights the factors that contribute to excellence in urban science teaching as pinpointed by five urban African‐American science teachers who have taught successfully in the urban system for over 10 years. These teachers shared their experiences and reflections on the qualities that contributed to their success and persistence as urban science teachers. Their ability to understand and care for their students was a major contributing factor; other contributing factors included in‐depth knowledge and love of science, caring and commitment to the whole child, effective classroom management strategies, high expectations and motivation of their students, and an understanding and acceptance of the varying parental involvement in the educational decisions about their child.     

Improved solution of displacements due to a compacting reservoir over a rigid basement

Geertsma’s analytical method is often used to compute strain and stress changes around a compacting geological reservoir. The present work extends Geertsma’s solution by adding a rigid layer beneath the compacting reservoir. Analytical formulae are presented for all the components of displacement of a point in the subsurface. Our derivation includes the correction of an error found in the paper written by Sharma in 1956.     

Binding of a 3He impurity to a screw dislocation in solid 4He

Using first-principles simulations for the probability density of finding a 3He atom in the vicinity of the screw dislocation in solid 4He, we determine the binding energy to the dislocation nucleus E(B)=0.8+/-0.1 K and the density of localized states at larger distances. The specific heat due to 3He features a peak similar to the one observed in recent experiments, and our model can also account for the observed increase in shear modulus at low temperature. We further discuss the role of 3He in the picture of superfluid defects.     

Structured Hybrid Nanoparticles via Surface‐Initiated ATRP of Methyl Methacrylate from Ordered Mesoporous Silica

Structured hybrid nanoparticles were synthesized via surface‐initiated atom transfer radical polymerization of MMA from ordered mesoporous silica (OMS) nanoparticles with various morphologies. The design of the OMS particles was adjusted to target either spherical core‐shell or cylindrical morphologies with a mean diameter below 400 nm. The polymer growth via ATRP from the silica surface was well‐controlled as demonstrated by the macromolecular characteristics of the grafted chains. Original hybrid multilayered nanoparticles composed of either a dense silica core or hollow core; an inner OMS shell showing radial orientation of the mesopores and an outer PMMA shell with controlled thickness were successfully prepared.