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Hunt CE Pasetto P Ansell RJ Haupt K 《Chemical communications (Cambridge, England)》2006,(16):1754-1756
The first pseudo-immunoassay which employs a molecularly imprinted receptor and a fluorescent probe, and quantifies the bound analyte directly using the fluorescence anisotropy of the polymer-probe-analyte suspension, is described. 相似文献
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Pamela Fraser‐Abder 《School science and mathematics》2010,110(5):238-246
This study highlights the factors that contribute to excellence in urban science teaching as pinpointed by five urban African‐American science teachers who have taught successfully in the urban system for over 10 years. These teachers shared their experiences and reflections on the qualities that contributed to their success and persistence as urban science teachers. Their ability to understand and care for their students was a major contributing factor; other contributing factors included in‐depth knowledge and love of science, caring and commitment to the whole child, effective classroom management strategies, high expectations and motivation of their students, and an understanding and acceptance of the varying parental involvement in the educational decisions about their child. 相似文献
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Geertsma’s analytical method is often used to compute strain and stress changes around a compacting geological reservoir. The present work extends Geertsma’s solution by adding a rigid layer beneath the compacting reservoir. Analytical formulae are presented for all the components of displacement of a point in the subsurface. Our derivation includes the correction of an error found in the paper written by Sharma in 1956. 相似文献
95.
Fabrice Audouin Hlne Blas Pamela Pasetto Patricia Beaunier Cdric Boissire Clment Sanchez Maud Save Bernadette Charleux 《Macromolecular rapid communications》2008,29(11):914-921
Structured hybrid nanoparticles were synthesized via surface‐initiated atom transfer radical polymerization of MMA from ordered mesoporous silica (OMS) nanoparticles with various morphologies. The design of the OMS particles was adjusted to target either spherical core‐shell or cylindrical morphologies with a mean diameter below 400 nm. The polymer growth via ATRP from the silica surface was well‐controlled as demonstrated by the macromolecular characteristics of the grafted chains. Original hybrid multilayered nanoparticles composed of either a dense silica core or hollow core; an inner OMS shell showing radial orientation of the mesopores and an outer PMMA shell with controlled thickness were successfully prepared.
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ZDM – Mathematics Education - The focus of this article is the well documented association between low working memory capacity and difficulty with mathematical word-problem solving. We begin... 相似文献
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Dr. Rianne M. Lord Dr. Markus Zegke Imogen R. Henderson Dr. Christopher M. Pask Dr. Helena J. Shepherd Prof. Patrick C. McGowan 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(2):495-500
This report presents a new library of organometallic iridium(III) compounds of the type [Cp*IrCl(L)] (Cp*=pentamethylcyclopentadienyl and L=a functionalized β-ketoiminato ligand) showing moderate to high cytotoxicity against a range of cancer cell lines. All compounds show increased activity towards colorectal cancer, with preferential activity observed against the immortalized p53-null colorectal cell line, HCT116 p53-/-, with sensitivity factors (SF) up to 26.7. Additionally, the compounds have excellent selectivity for cancerous cells when tested against normal cell types, with selectivity ratios (SR) up to 35.6, contrary to that of cisplatin, which is neither selective nor specific for cancerous cells (SF=0.43 and SR=0.7–2.3). This work provides a preliminary understanding of the cytotoxicity of iridium compounds in the absence of p53 and has potential applications in treatment of cancers for which the p53 gene is absent or mutant. 相似文献
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