Polarized target asymmetry in π+ photoproduction between 0.3 and 1.0 GeV at 130°

The polarized target asymmetry for γ + p → π⁺ + n was measured at c.m. angles around 130° for the energy range between 0.3 and 1.0 GeV. A magnetic spectrometer system was used to detect π⁺ mesons from the polarized butanol target. The data show two prominent positive peaks at 0.4 and 0.8 GeV and a deep minimum at 0.6 GeV. These features are well reproduced by the phenomenological analysis made by us.     

Relationship of stress to uniaxial strain in crosslinked poly(dimethylsiloxane) over the full range from large compressions to high elongations

Experiments on inflated sheets of crosslinked poly(dimethylsiloxane) covering a sixfold range of compression are combined with measurements in elongation conducted on specimens from the same sample to obtain the relationship of stress to strain over a 24-fold range in the extension ratio λ₁. With increase in λ the reduced force [f] ≡ f(λ₁ – λ)^?1 rises to a maximum near λ = 1.2–1.4, then decreases very slowly with further increase in λ. The form of the relationship of [f] to λ confirms recent theory.     

S‐Functionalized Cysteine: Powerful Ligands for the Labelling of Bioactive Molecules with Triaquatricarbonyltechnetium‐99m(1+) ([99mTc(OH2)3(CO)3]+)

S‐Alkylated cysteines are used as efficient tridentate N,O,S‐donor‐atom ligands for the fac‐[M(CO)₃]⁺ moiety (M=^99mTc or Re). Reaction of (Et₄N)₂[ReBr₃(CO)₃] ( 3 ) with the model S‐benzyl‐L ‐cysteine ( 2 ) leads to the formation of [Re( 2′ )(CO)₃] ( 4 ) as the exclusive product ( 2′ =C‐terminal anion of 2 ). The tridentate nature of the alkylated cysteine in 4 was established by X‐ray crystallography. Compound 2 reacts with [^99mTc(OH₂)₃(CO)₃]⁺ under mild conditions (10⁻⁴ M , 50°, 30 min) to afford [^99mTc( 2′ )(CO)₃] ( 5 ) and represents, therefore, an efficient chelator for the labelling of biomolecules. L ‐Cysteine, S‐alkylated with a 3‐aminopropyl group (→ 7 ), was conjugated via a peptide coupling sequence with Coα‐[α‐(5,6‐dimethyl‐1H‐benzimidazolyl)]‐Coβ‐cyanocobamic b‐acid ( 6 ), the b‐acid of cyanocob(III)alamin (vitamin B₁₂) (Scheme 3). More convenient was a one‐pot procedure with a derivative of vitamin B₁₂ comprising a free amine group at the b‐position. This amine 15 was treated with NHS (N‐hydroxysuccinimide)‐activated 1‐iodoacetic acid 14 to introduce an I‐substituent in vitamin B₁₂. Subsequent addition of unprotected L ‐cysteine resulted in nucleophilic displacement of the I‐atom by the S‐substituent, affording the vitamin B₁₂ alkylated cysteine fragment 17 (Scheme 4). The procedure was quantitative and did not require purification of intermediates. Both cobalamin–cysteine conjugates could be efficiently labelled with [^99mTc(OH₂)₃(CO)₃]⁺ ( 1 ) under conditions identical to those of the model complex 5 . Biodistribution studies of the cobalamin conjugates in mice bearing B10‐F16 melanoma tumors showed a tumor uptake of 8.1±0.6% and 4.4±0.5% injected dose per gram of tumor tissue after 4 h and 24 h, respectively (Table 1).     

Observation of monochromatic X-ray radiation from 900 MeV electrons transmitting through a diamond crystal

A new source of monochromatic X-ray radiation from a relativisti? electron beam transmitted through a crystal target is experimentally observed.     

Interaction of schiff bases with indandione-1, 3

A new method was examined for the synthesis of multinuclear systems based on dihydroquinoline and quinoline, consisting of the interaction of arylidene--naphthylamines with indandione-1, 3. The reaction of arylidene anilines with indandione-1,3 leads to the formation of arylidenindandiones-1, 3.     

Hydrogen activation on copper catalytic sites in stereoselective alkyne hydrogenation

The interaction of hydrogen with copper clusters has been studied using EHM/AP method (extended Hückel method with Anderson's potential). Copper atoms are shown to form a dihydride structure with a high stability, which is due to the low mobility of atomic hydrogen on the surface. The formation of this complex appears to be favorable for concerted hydrogenation of acetylenes tocis-olefins.