Determination of the absolute structure of (+)-akaterpin

We describe the total synthesis and structural determination of (+)-akaterpin (1), an inhibitor of phosphatidylinositol-specific phospholipase C (PI-PLC). The key features of the synthetic strategy include the resolution of β,γ-unsaturated ketone (±)-2a with chiral sulfoximine 6. The absolute stereochemistry was determined by comparison of the specific optical rotation data of (+)-1 and (-)-1 with that of natural akaterpin.     

Catenane gel: synthesis of high molecular weight poly[2]catenanes by Sonogashira coupling polymerization

A first catenane polymer gel was obtained by Sonogashira coupling reaction of diiodo[2]catenane and 4,4′-diethynylbiphenyl. Because of the linearity and rigidity of the ethynylene group formed in the coupling reaction, the formation of undesired cyclic dimer was inhibited, and a very high molecular weight (M_n > 2.3 × 10⁵) poly[2]catenane was synthesized. The polymer was gelated without any chemical cross-linkage and swelled in DMF.     

Influence of ZIF-8 modification on performance of ZnO-based dye-sensitized solar cells

Journal of Solid State Electrochemistry - Metal–organic frameworks (MOFs) were used to modify the surface of nanoparticulate ZnO electrodes, aiming at enhancing the performance of...     

Recent progress of photo‐resin for rapid prototyping, “resin for stereolithography”

A main goal for manufacturing systems is to shorten lead‐time for the development of new products. An important challenge is to make sound decisions at early stages of product development where committed costs are low which leads us to obtain a lower total cost. This could mean that incurred costs are higher in the beginning where more work has to be done in terms of learning the market, developing the product and the production system. An important feature is to avoid changes at later stages where the incurred costs are high. The stereolithography using photo curable liquid resin is important for the manufacturing. The technology based on the stereolithography has been widely accepted due to the phenomena of spreading “Information Technology (IT)” and three‐dimensional computer aided design (3D CAD) system. The stereolithography technique has become very popular in the field of automotive, home‐electronics industries. In this paper the photo curable liquid resins for the stereolithography system are reviewed.