Determination of gold and silver in copper concentrates, using k0 based neutron activation analysis

Procedures for the determination of gold and silver in copper concentrates, using k ₀ based neutron activation analysis, were developed and tested. The effects of gamma-ray self attenuation, neutron self-shielding and spectral interference were considered; precision, accuracy, and detection limits were studied by repeated analysis of copper concentrate internal reference materials. The analytical results have shown good precision and satisfactory accuracy in concordance with the detection limit and range of concentration.     

在硅胶表面制备牛血红蛋白分子印迹聚合物

采用表面印迹法, 以乙烯基三甲氧基硅烷修饰的硅胶为载体, 丙烯酰胺为功能单体, N,N-亚甲基双丙烯酰胺为交联剂, 并将改性聚乙烯醇(PVA)作为辅助识别聚合物链(ARPCs)引入聚合体系中, 制备了牛血红蛋白分子印迹聚合物(MIP). 实验使用红外光谱分析了改性PVA的结构特征, 用扫描电镜(SEM)观察MIP的表面形貌, 考察了ARPCs的含量对MIP吸附性能的影响. 吸附动力学实验研究表明, 聚合体系中ARPCs的引入使MIP对模板牛血红蛋白(BHb)的吸附量明显提高|十二烷基磺酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)结果显示, MIP对BHb的特异性吸附能力明显提高.     

Quantitative Analysis of Cyproterone Acetate and Ethinylestradiol in Tablets by use of Planar Chromatography

JPC – Journal of Planar Chromatography – Modern TLC - This paper describes a simple, rapid, and reliable HPTLC procedure for the determination of cyproterone acetate and...     

TRANSFER MECHANISM OF QUININE DRUG ACROSS THE OIL/WATER (O/W) INTERFACE

The transfer phenomena of quinine drug at the aqueous 1,2- dichloroethane (DCE)interface have been studied by the current- scanning polarography. The relationships be-tween the wave height and pH of aqueous phase, concentration of quinine as well as therate of water drop are discussed. The effect of supporting electrolyte, buffer solution andthe nature of organic solvent on the polarographic wave is studied. The transfer char-acteristics of quinine in aqueous phase and in organic phase are compared, The mono- pro-tonated and diprotonated quinines can both transfer at the interface so as to produce twopolarographic waves. The transfer process of quinine at the interface is simultaneouslycontrolled by diffusion and reestablishment of the disturbed protonated equilibrium ofquinine. A further investigation is made by chronopotentiometry. On the basis of thetheoretical analysis, the formulae of the limiting current are derived and discussed. Thetheoretical results are in agreement with the experimental ones.     

Qualitative analysis of ion tracks in Makrofol E

The track radius calculation reported by Tombrello was applied to experimental data of tracks from several ions and energies in Makrofol E. Qualitative analysis of ion tracks in this material is discussed. These data were also compared with values calculated using the Continuum Distorted Wave-Eikonal Initial State approximation     

A memetic algorithm based on a NSGAII scheme for the flexible job-shop scheduling problem

The Flexible Job-Shop Scheduling Problem is concerned with the determination of a sequence of jobs, consisting of many operations, on different machines, satisfying several parallel goals. We introduce a Memetic Algorithm, based on the NSGAII (Non-Dominated Sorting Genetic Algorithm II) acting on two chromosomes, to solve this problem. The algorithm adds, to the genetic stage, a local search procedure (Simulated Annealing). We have assessed its efficiency by running the algorithm on multiple objective instances of the problem. We draw statistics from those runs, which indicate that this Memetic Algorithm yields good and low-cost solutions.     

Determination of cationic surfactants in pharmaceutical disinfectants using a new sensitive potentiometric sensor

A new sensitive potentiometric surfactant sensor was prepared based on a highly lipophilic 1,3-didecyl-2-methyl-imidazolium cation and a tetraphenylborate antagonist ion. This sensor was used as a sensing material and incorporated into the plasticized PVC-membrane. The sensor responded fast and showed a Nernstian response for investigated surfactant cations: cetylpyridinium chloride (CPC), hexadecyltrimethylammonium bromide (CTAB) and Hyamine with slope 59.8, 58.6 and 56.8 mV/decade, respectively. The sensor served as an end-point detector in ion-pair surfactant potentiometric titrations using sodium tetraphenylborate as titrant. Several technical grade cationic surfactants and a few commercial disinfectant products were also titrated, and the results were compared with those obtained from a two-phase standard titration method. The sensor showed satisfactory analytical performances within a pH range of 2-11, and exhibited excellent selectivity performance for CPC compared to all of the organic and inorganic cations investigated. The influence of the nonionic surfactants on the shape of titration curves was negligible if the mass ratio of ethoxylated nonionic surfactants and cationic surfactants (EONS:CS) was not greater than 5.     

Investigation of solvolysis kinetics of new synthesized fluocinolone acetonide C-21 esters--an in vitro model for prodrug activation

In this study the solvolysis of newly synthesized fluocinolone acetonide C-21 esters was analysed in comparison with fluocinonide during a 24-hour period of time. The solvolysis was performed in an ethanol-water (90:10 v/v) mixture using the excess of NaHCO?. The solvolytic mixtures of each investigated ester have been assayed by a RP-HPLC method using isocratic elution with methanol-water (75:25 v/v); flow rate 1 mL/min; detection at 238 nm; temperature 25 °C. Solvolytic rate constants were calculated from the obtained data. Geometry optimizations and charges calculations were carried out by Gaussian W03 software. A good correlation (R = 0.9924) was obtained between solvolytic rate constants and the polarity of the C-O2 bond of those esters. The established relation between solvolytic rate constant (K) and lipophilicity (cLogP) with experimental anti-inflammatory activity could be indicative for topical corticosteroid prodrug activation.     

Tempered generalized functions and Hermite expansions

In this work we introduce an algebra of tempered generalized functions. The tempered distributions are embedded in this algebra via their Hermite expansions. The Fourier transform is naturally extended to this algebra in such a way that the usual relations involving multiplication, convolution and differentiation are valid. Furthermore, we give a generalized Itô formula in this context and some applications to stochastic analysis.     

Enhanced speciation in particle swarm optimization for multi-modal problems

In this paper, we present a novel multi-modal optimization algorithm for finding multiple local optima in objective function surfaces. We build from Species-based particle swarm optimization (SPSO) by using deterministic sampling to generate new particles during the optimization process, by implementing proximity-based speciation coupled with speciation of isolated particles, and by including “turbulence regions” around already found solutions to prevent unnecessary function evaluations. Instead of using error threshold values, the new algorithm uses the particle’s experience, geometric mean, and “exclusion factor” to detect local optima and stop the algorithm. The performance of each extension is assessed with leave-it-out tests, and the results are discussed. We use the new algorithm called Isolated-Speciation-based particle swarm optimization (ISPSO) and a benchmark algorithm called Niche particle swarm optimization (NichePSO) to solve a six-dimensional rainfall characterization problem for 192 rain gages across the United States. We show why it is important to find multiple local optima for solving this real-world complex problem by discussing its high multi-modality. Solutions found by both algorithms are compared, and we conclude that ISPSO is more reliable than NichePSO at finding optima with a significantly lower objective function value.