Nonaqueous oxidation of phosphites to phosphates in nucleotide synthesis

$\text{m}$-Chloroperbenzoic acid in methylene chloride represents a rapid non-aqueous method for the conversion of phosphites to phosphates during oligonucleotide synthesis both in solution and on a solid support.     

Evolved CYP102A1 (P450BM3) variants oxidise a range of non-natural substrates and offer new selectivity options

The evolution of CYP102A1 variants with enhanced activity and altered specificity characteristics.     

N-levulination of nucleosides

Procedures have been developed for the synthesis of the N-levulinyl derivatives of cytidine, adenosine and guanosine.     

Spin waves,vortices, fermions,and duality in the Ising and Baxter models

Field-theoretic methods are applied to a number of two-dimensional lattice models with Abelian symmetry groups. It is shown, using a vortex + spin-wave decomposition, that the Z_p^? Villain models are related to a class of continuum field theories with analogous duality properties. Fermion operators for these field theories are discussed. In the case of the Ising model, the vortices and spin-waves conspire to produce a free, massive Majorana field theory in the continuum limit. The continuum limit of the Baxter model is also studied, and the recent results of Kadanoff and Brown are rederived and extended.     

Analysis of Pure Rotational and Vibration‐rotational Spectra of NaCl X 1Σ+ and Quantum‐chemical Calculation of Related Molecular Properties

We fitted published frequency and wave number data for pure rotational and vibration‐rotational spectra, respectively, of ²³Na³⁵Cl and ²³Na³⁷Cl to derive parameters related to potential energy and to the rotational g factor. For comparison with these experimental data we undertook quantum‐chemical computation of adiabatic corrections, rotational and vibrational g factors, electric dipolar moment and its derivative as a function of internuclear distance in a range near R_e as a test of an algebraic approach to spectral analysis; experimental, 0.0287 ± 0.0014, and calculated, 0.02149, values of g_r at R_e are in moderate agreement. The combined results are discussed from a point of view of computational spectrometry.     

Large-N lattice models with mixed actions

U(N) lattice gauge theories and spin systems with mixed fundamental and adjoint representation actions are studied. Exact results are found for two-dimensional gauge theories and one-dimensional spin chains. Phase diagrams for higher-dimensional systems are found using mean field theory. Various implications of this work are discussed.