Convenient synthesis of 1-norbornyl-5-R-1H-1,2,3-triazole-4-carboxylic acids

Russian Journal of Organic Chemistry - A convenient procedure was developed for the synthesis of 2-azidobicyclo[2.2.1]heptane whose click reaction with phenylacetylene afforded...     

A Convenient Synthesis of [1,2,3]Triazolo[1,5-a]quinoline

Russian Journal of Organic Chemistry - The reaction of methyl 2-azido-5-bromobenzoate with ethyl 4-(ethylsulfanyl)-3-oxobutanoate was used to synthesize ethyl...     

Reaction of Arendiazonium Salts and SO2with α-Nitroolefins

In reaction of -nitrostyrene and 2-(2-nitrovinyl)furan with arenediazonium chlorides and SO2 in the presence of copper(II) chloride products were obtained resulting from addition of arylsulfonyl group and a hydrogen atom across the C=C bond: 2-nitro-1-phenylethylsulfonylarenes and 2-(1-arylsulfonyl-2-nitroethyl)furans respectively. An anion-radical mechanism of the reaction was suggested.     

Heterocycles Synthesis Based on Arylation Products of Unsaturated Compounds: XII. Reactions of 2-Aryl-1,4-benzoquinones with Dithiol Compounds

Reactions of 2-aryl-1,4-benzoquinones with disodium (2,2-dicyano-1,1-ethylene)dithiolate gave rise either to 1,3-benzodithiol or 1,3-benzoxathiol depending on the character of the aryl substituent. 2-Aryl-1,4-benzoquinones reacted with 3-methylsulfanyl-3-sulfanyl-2-cyanoacrylamide with a higher selectivity: 2-(7-Aryl-5-hydroxy-1,3-benzoxathiol-2-ylidene)-2-cyanoacetamides were obtained in a high yield.__________Translated from Zhurnal Organicheskoi Khimii, Vol. 41, No. 5, 2005, pp. 762–766.Original Russian Text Copyright © 2005 by Obushak, Martyak, Matiichuk.     

A new domino-Knoevenagel-hetero-Diels-Alder reaction

Various novel 3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazol-2-ones were synthesized in 60-80% yields via domino-Knoevenagel-hetero-Diels-Alder reactions of 4-thioxo-1,3-thiazolidin-2-one with 3,7-dimethyl-6-octenal, 2-allyloxybenzaldehydes and 2-formylphenyl (E)-3-aryl-2-propenoates with base catalysis. The possibility of stereo- and regioselective cycloaddition was investigated.     

Synthesis of heterocycles on the basis of anion arylatied products of unsaturated-compounds. Part 4. Cyclocondensation of 3-aryl-2-halo(thiocyanate)propionitriles

Products from the anionic arylation of acrylonitrile show ring closure on interaction with S,N-nucleophiles. The reactions of 3-aryl-2-halopropionitriles with thiourea and ammonium N-phenyldithiocarbamate give respectively 2,4-diimino-5-arylmethylthiazolidines and 4-amino-5-arylmethyl-3-phenyl-4-thiazolin-2-thiones. Hydrogen bromide reacts with 3-aryl-2-thiocyanatopropionitriles to give 4-amino-5-arylmethyl-2-bromothiazoles.See [1] for Part 3.Ivan Franko L'vov State University, L'vov 2906602, Ukraine. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 97–100, January, 1999.     

A four-step domino Knoevenagel–hetero-Diels–Alder reaction

A new, catalyst-free, domino Knoevenagel–hetero-Diels–Alder elimination oxidation reaction is reported. 5-Aryl-2H,6H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazol-2-ones are formed in moderate to good yields via reaction of 2-(3-aryl-3-chloro-2-propenyloxy)benzaldehydes with 4-thioxo-1,3-thiazolidin-2-one.     

A Simple and Efficient Synthesis of Ethyl 1‐Aryl‐4‐formyl‐1H‐pyrazole‐3‐carboxylates

A new simple and convenient method of synthesis of ethyl 1‐aryl‐4‐formyl‐1H‐pyrazole‐3‐carboxylates from aromatic amines via diazonium salts has been developed. Hydrolysis and hydrazinolyization of these compounds has been investigated.     

Synthesis,absorption spectra,and luminescence properties of dihydrobenzoacridinone derivatives

9,9-Dimethyl-12-[(5-aryl-2-furyl) (or 5-aryl-2-thienyl, or 5-aryl-1-methyl-1H-pyrrolyl)]-7,8,9,10,11,12-hexahydrobenzo[a]acridin-11-ones were synthesized, and their absorption and luminescence spectrum characteristics in ethanol at room temperature and at 77 K were studied. The spectra suggest the existence of these compounds in a liquid solution as mixtures of conformers, each of which is characterized by its own absorption and fluorescence spectra.     

Metal-Free Synthesis of 1,5-Disubstituted 1,2,3-Triazoles

Russian Journal of Organic Chemistry - The main synthetic approaches to 1,5-disubstituted 1,2,3-triazoles are considered. It is shown that the cycloaddition of aryl azides to phosphorus ketoylides...