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81.
Summary A module B over a commutative domain R is said to be a Baer module if Ext
R
1
(B, T)=0for all torsion R-modules T. The case in which R is an arbitrary valuation domain is investigated, and it is shown that in this case Baer modules are necessarily free. The method employed is totally different from Griffith's method for R=Z which breaks down for non-hereditary rings.This research was partially supported by NSF Grants DMS-8400451 and DMS-8500933. 相似文献
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Xonotlite alone or made more basic by doping of potassium -butoxide catalyses the title reaction between aromatic aldehydes and malononitrile or alkyl cyanoacetates. At ambient temperatures, this procedure specifically gives high yields of olefinic Knoevenagel products. 相似文献
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13C-NMR longitudinal relaxation rates are analysed with the Woessner equations: in CDCl3 solution at room temperature, 1-phenyladamantane has rotational diffusion coefficients R‖ = 8.1 × 1010 rad · s?1 and R⊥ = 1.1 × 1010 rad · s?1 corresponding to high motional anisotropy (σ = 7.4). 相似文献
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Rebeka Torok Klaudia Horompoly Marton Szigeti Andras Guttman Marta Vitai Laszlo Koranyi Gabor Jarvas 《Molecules (Basel, Switzerland)》2021,26(21)
Currently, diagnosing type 2 diabetes (T2D) is a great challenge. Thus, there is a need to find rapid, simple, and reliable analytical methods that can detect the disease at an early stage. The aim of this work was to shed light on the importance of sample collection options, sample preparation conditions, and the applied capillary electrophoresis bioanalytical technique, for a high-resolution determination of the N-glycan profile in human blood samples of patients with type 2 diabetes (T2D). To achieve the profile information of these complex oligosaccharides, linked by asparagine to hIgG in the blood, the glycoproteins of the samples needed to be cleaved, labelled, and purified with sufficient yield and selectivity. The resulting samples were analyzed by capillary electrophoresis, with laser-induced fluorescence detection. After separation parameter optimization, the capillary electrophoresis technique was implemented for efficient N-glycan profiling of whole blood samples from the diabetic patients. Our results revealed that there were subtle differences between the N-glycan profiles of the diabetic and control samples; in particular, two N-glycan structures were identified as potential glycobiomarkers that could reveal significant changes between the untreated/treated type 2 diabetic and control samples. By analyzing the resulting oligosaccharide profiles, clinically relevant information was obtained, revealing the differences between the untreated and HMG-CoA reductase-inhibitor-treated diabetic patients on changes in the N-glycan profile in the blood. In addition, the information from specific IgG N-glycosylation profiles in T2D could shed light on underlying inflammatory pathophysiological processes and lead to drug targets. 相似文献