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491.
In this paper we prove that for $p > 13649$ equations of the form $x^{13} + y^{13} = Cz^{p}$ have no non-trivial primitive solutions $(a,b,c)$ such that $13 \not \mid c$ for an infinite family of values for $C$ . Our method consists on relating a solution $(a,b,c)$ to the previous equation to a solution $(a,b,c_1)$ of another Diophantine equation with coefficients in $\mathbb Q (\sqrt{13})$ . Then we attach to $(a,b,c_1)$ a Frey curve $E_{(a,b)}$ defined over $\mathbb Q (\sqrt{13})$ that is not a $\mathbb Q $ -curve. We prove a modularity result of independent interest for certain elliptic curves over totally real abelian number fields satisfying some local conditions at $3$ . This theorem, in particular, implies modularity of $E_{(a,b)}$ . This enables us to use level lowering results and apply the modular approach via Hilbert cuspforms over $\mathbb Q (\sqrt{13})$ to prove the non-existence of $(a,b,c_1)$ and, consequently, of $(a,b,c)$ .  相似文献   
492.
In this work, we present a new algorithm for solving complex multi-stage optimization problems involving hard constraints and uncertainties, based on dynamic and multi-parametric programming techniques. Each echelon of the dynamic programming procedure, typically employed in the context of multi-stage optimization models, is interpreted as a multi-parametric optimization problem, with the present states and future decision variables being the parameters, while the present decisions the corresponding optimization variables. This reformulation significantly reduces the dimension of the original problem, essentially to a set of lower dimensional multi-parametric programs, which are sequentially solved. Furthermore, the use of sensitivity analysis circumvents non-convexities that naturally arise in constrained dynamic programming problems. The potential application of the proposed novel framework to robust constrained optimal control is highlighted.  相似文献   
493.
We propose a global optimisation approach for the solution of various classes of bilevel programming problems (BLPP) based on recently developed parametric programming algorithms. We first describe how we can recast and solve the inner (follower’s) problem of the bilevel formulation as a multi-parametric programming problem, with parameters being the (unknown) variables of the outer (leader’s) problem. By inserting the obtained rational reaction sets in the upper level problem the overall problem is transformed into a set of independent quadratic, linear or mixed integer linear programming problems, which can be solved to global optimality. In particular, we solve bilevel quadratic and bilevel mixed integer linear problems, with or without right-hand-side uncertainty. A number of examples are presented to illustrate the steps and details of the proposed global optimisation strategy.  相似文献   
494.
    
Indium molybdenum oxide (IMO) thin films were radio-frequency (RF) sputtered at room temperature (RT) and studied as a function of base pressure (BP). The crystallinity of the films is decreased with the increase in BP. A maximum mobility (μ) of 49.6 cm2 V−1 s−1 was obtained from the IMO films deposited at RT without any post-annealing treatment. The electronic behaviour of the deposited films was investigated by temperature-dependent (100–550 K) Hall measurements. Study on the scattering mechanisms based on the experimental data and theoretical models show that the ionized scattering centres are dominating. The films possess wide work function (4.91 eV) and high transmittance (> 70%) over visible and near infrared (NIR) range. The obtained results, especially the high work function and NIR transmittance, are very promising particularly in applications such as optical detectors and solar cells.https://doi.org/10.1209/0295-5075/97/36002  相似文献   
495.
ABSTRACT

As part of our studies on glycolipidic liquid crystals, we have investigated some molecules comprising a steroid moiety. These systems can exhibit several types of structures depending on their polarity pattern based on the number of polar and non-polar moieties and their resulting molecular shape. Therefore, to aid describing such systems, we have proposed a specific classification based on this polarity pattern. Many compounds in this family are natural products, which possess important biological properties. Some of the compounds have bolaphilic structures, with both a steroid and a fatty alkyl chain attached to the carbohydrate moiety, such as either the β-galactoside BbGL-1 or the α-glucoside α-CAG that are found in the membranes of the pathogens Borrelia burgdorferi and Helicobacter pylori, respectively. In this account, after a brief introduction on liquid crystalline glycolipids, we focus on carbohydrate–steroid hybrids, summarising our previous work on glycosteroids prepared by the CMGL-synthon strategy, and reporting our preliminary results on the thermotropic behaviour of acyl steroid glycosides (ASG), namely cholesteryl 6-O-acyl-β-gluco- and -galacto-pyranosides.  相似文献   
496.
    
The first enantioconvergent palladium‐catalyzed Fukuyama cross‐coupling of racemic benzylic organozinc reagents with thioesters has been developed. The reaction furnishes enantioenriched acyclic α‐disubstituted ketone products in good yields and high enantioselectivities. A broad substrate scope is achieved under mild reaction conditions to prevent racemization of the potentially labile tertiary stereocenters.  相似文献   
497.
    
An efficient metal‐free oxyarylation of electron‐poor alkynes with pyridine N‐oxides has been developed. This transformation affords meta‐substituted pyridines analogous to the drug metyrapone in high regioselectivities. Density functional theory (DFT) calculations provided important insight into the mechanism. Evaluation of the inhibitory properties revealed the most active CYP11B1 inhibitor of these derivatives, with two‐digit nanomolar inhibitory activity akin to that of metyrapone.  相似文献   
498.
    
A new bis(µ-chlorido)-bridged cobalt(II) complex [Co2(µ-Cl)2(HL2)4][CoCl4] (1), where HL2 is a silyl-containing Schiff base, was synthesised. The structure of this compound was established by X-ray crystallography revealing a zwitterionic form adopted by the organic ligand. The temperature dependence of the magnetic susceptibility and the field dependence of the magnetisation indicate the presence of ferromagnetic interactions between paramagnetic d7 cobalt(II) centres (SCo = 3/2). The exchange coupling parameter J(Co1–Co2) = +7.0 cm–1 extracted from broken-symmetry (BS) DFT calculations agrees well with the value of +8.8 cm–1 determined from the experimental data by fitting them with the Hamiltonian . Electrochemical studies indicate that complex 1 is inefficient as a catalyst in electrochemical reduction of protons. One of the reasons is the low stability of the complex in solution. In contrast, 1 acts as an effective homogeneous (pre)catalyst in the microwave-assisted neat oxidation of cyclohexane with aqueous tBuOOH (TBHP). The possible mechanism of catalytic oxidation and other advantages of using 1 in the oxidation of cycloalkanes are discussed.  相似文献   
499.
    
Molecular recognition of small molecules and ions by artificial receptors in microheterogeneous media such as micelles and vesicles can, in principle, provide better models of biological systems in comparison with bulk solutions. In this work we have investigated the complexation of an organic fluorescent probe with amphiphilic calixarene receptor below and above the critical micelle concentration (CMC). For concentrations below the CMC, the probe forms a host–guest complex with the calixarene behaving like a traditional host–guest system operating in bulk solution. Above the CMC, multiple equilibrium processes are established and the probe can exchange between the recognition site of the calixarene in the monomeric state, micellized state and/or the micellar hydrophobic core. Careful analysis of the results obtained from NMR spectroscopy and fluorescence experiments allowed us to propose a quantitative model to describe the system. The increment of the local concentration of Na+ counterions at the Stern layer displace the dye to the micelle core through competitive binding of Na+ in the cavity of the receptor and is decisive for the observed self‐sorting behavior.  相似文献   
500.
    
The catecholamines adrenaline, noradrenaline, dopamine, dopa and isoprenaline were oxidized into their respective aminochromes: adrenochrome, noradrenochrome, dopaminochrome, dopachrome and isoprenochrome. Tandem mass spectrometry (MS/MS) fragmentation patterns were examined for the five aminochromes in order to establish a general structural assignment of these oxidation products by electrospray mass spectrometry. Although protonated aminochromes undergo similar fragmentation patterns with a characteristic consecutive loss of two carbonyl groups, the presence of different substituents in the parent compounds led to significant changes in the CID spectra. This feature is more evident for isoprenochrome and dopachrome, especially for the latter where the MS/MS spectrum is dominated by the loss of formic acid. A general pattern of fragmentation for aminochromes is proposed, which should provide a suitable basis to aid their characterization in studies in vivo or in vitro.  相似文献   
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