排序方式: 共有107条查询结果,搜索用时 9 毫秒
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Marcos A.P Martins Claudio M.P Pereira Nilo E.K Zimmermann Wilson Cunico Sidnei Moura Paulo Beck Nilo Zanatta Helio G Bonacorso 《Journal of fluorine chemistry》2003,123(2):261-265
A series of 10 heterocycles was obtained from the reaction of 1,1,1-trifluoro-4,4-diethoxy-3-buten-2-one and 1,1,1,2,2-pentafluoro-4,4-diethoxy-3-penten-2-one with different dinucleofiles (hydrazine, methyl hydrazine, hydroxylamine and sodium cyanide). The pyrazoles, 4,5-dihydroisoxazoles and pyrrolidinones polyfluoroalkyl substituted were obtained in moderate to good yields under mild conditions. 相似文献
33.
Efficient microwave-assisted synthesis of 1-aryl-4-dimethylamino methyleno-pyrrolidine-2,3,5-triones
Pâmela S. Vargas Fernanda A. Rosa Lilian Buriol Mariane Rotta Dayse N. Moreira Clarissa P. Frizzo Helio G. Bonacorso Nilo Zanatta Marcos A.P. Martins 《Tetrahedron letters》2012,53(25):3131-3134
A microwave-assisted synthesis of a series of 1-aryl-4-dimethylaminomethylene pyrrolidine-2,3,5-triones from the cyclocondensation reaction of ethyl 5,5,5-trichloro-3-dimethylamino methylene-2,4-dioxopentanoate with aniline, 3- or 4-substituted anilines [where the substituents = 3-Me, 3-OMe, 3-OH, 4-Me, 4-F, 4-Cl, 4-Br, 4-NO2, and 4-COMe] is reported. This process is an efficient alternative to the conventional thermal heating and furnishes the products in a short reaction time (ca. 13 min), under mild conditions and in moderate to good yields (50–76%). 相似文献
34.
Lilian Buriol Taiana S. München Clarissa P. Frizzo Mara R.B. Marzari Nilo Zanatta Helio G. Bonacorso Marcos A.P. Martins 《Ultrasonics sonochemistry》2013,20(5):1139-1143
Pyrazolo[1,5-a]pyrimidines were synthesized via the ultrasonic sonochemical method using the cyclocondensation reaction of 4-alkoxy-1,1,1-trifluoro-3-alken-2-ones [CF3C(O)CH = C(R)(OMe) – where R = Me, Bu, i-Bu, Ph, 4-Me–C6H4, 4-F–C6H4, 4-Cl–C6H4, 4-Br–C6H4, naphth-2-yl and biphen-4-yl] – with 3-amino-5-methyl-1H-pyrazole in the presence of EtOH for 5 min. This methodology has several advantages, for example, it is a simple procedure, it has an easy work-up, mild conditions, short reaction times (5 min) and produces satisfactory yields (61–98%). 相似文献
35.
Evaluation by empirically derived equations for the Substituent effect (α, β, γ, δ) on the 13C NMR chemical shifts for C-3, C-4. C-5 and halomethyl-substituent carbon (C-6) in isoxazoles 1-5 [where C-3 substituent (R1) = H, alkyl or phenyl, C-4 Substituent (R2) = H, alkyl, and C-5 substituent (R3) = di-or trihalomethyl, methyl and H], taking as reference the compound la, is reported. From the calculated values for the α, β, γ, δ effects for each substituent it was possible to estimate the chemical shift of each carbon of the compounds 1–5. The 13 C chemical shifts of the C-3, C-4, C-5, C-6 of these compounds, can be estimated with good precision: 94% of the calculated chemical shifts are found to be within ±1.0ppm, and 100% are found to be within ±1.5ppm. 相似文献
36.
Nilo C. Bobillo‐Ares 《International Journal of Mathematical Education in Science & Technology》2013,44(6):773-780
After an elementary introduction to integral representation of functions, the close relationship existent between Fourier analysis and physical systems characterized by invariant linear operators is analysed. 相似文献
37.
Helio G Bonacorso Hilario Lewandowski Roberta L Drekener Michelle B Costa Claudio M.P Pereira Arci D Wastowski Clóvis Peppe Marcos A.P Martins Nilo Zanatta 《Journal of fluorine chemistry》2003,122(2):159-163
A new series of six 3-aryl-5-hydroxy-5-trifluoromethyl-4,5-dihydro-1H-1-picolinoylpyrazole hydrochlorides were synthesised in one-step in high yields by the reaction of β-methoxyvinyl trifluoromethyl ketones with 2-pyridinecarboxamidrazone in the presence of hydrochloric acid. The hydrochloride salts were easily converted to the respective new series of free trifluoromethylated 4,5-dihydro-1H-1-picolinoylpyrazoles using triethylamine in anhydrous diethyl ether. X-ray structure and NMR data from the pyrazole hydrochlorides are reported. 相似文献
38.
Helio G. Bonacorso Guilherme P. Bortolotto Jussara Navarini Liliane M.F. Porte Carson W. Wiethan Nilo Zanatta Marcos A.P. Martins Alex F.C. Flores 《Journal of fluorine chemistry》2010,131(12):1297-1301
This study describes a simple and efficient procedure to synthesize a novel series of fourteen 4-substituted N-(5-pyridinyl-1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)pyrimidin-2-amines, where the 4-substituents are H, CH3, C6H5, 4-FC6H4, 4-CH3C6H4, 4-CH3OC6H4 and 2-Furyl; from the cyclocondensation reaction of N-[5-(pyridinyl)-1H-1,2,4-triazol-3-yl]guanidines with 4-alkoxy-4-alkyl(aryl/heteroaryl)-1,1,1-trifluoroalk-3-en-2-ones. The reactions were carried out in ethanol under reflux for 18 h and led to 40-68% yields. N-(Pyridyl-triazolyl)guanidine precursors were further obtained from reactions of cyanoguanidine with nicotinic or isonicotinic acid hydrazides and the halogenated enones from trifluoroacetylation of enolethers or acetals. 相似文献
39.
Helio G. Bonacorso Carson W. WiethanChaiene R. Belo Maiara C. MoraesMarcos A.P. Martins Nilo Zanatta 《Tetrahedron letters》2014
The results of allylation reactions employing allylaluminum reagents are described for 5-substituted (2,6-difluorobenzyl)-4-trifluoro(chloro)acetyl-1H-1,2,3-triazoles (1), in which the 5-substituents are H, Me, and Ph. The allylating reagents were generated in situ by the catalytic insertion of aluminum into allyl and crotyl bromides (2), in order to furnish a new series of twelve trihalomethyl triazolyl homoallylic alcohols (3) at yields of up to 94%. The excellent reactivity of these organoallyl reagents is highlighted as an economical alternative to the indium-mediated reactions to produce homoallylic alcohols, which are important building blocks in organic synthesis. 相似文献
40.
Martins MA Pereira CM Cunico W Moura S Rosa FA Peres RL Machado P Zanatta N Bonacorso HG 《Ultrasonics sonochemistry》2006,13(4):364-370
A convenient method for the preparation of 5-hydroxy-5-trihalo-4,5-dihydroisoxazoles and beta-enamino trihalomethyl ketones, from the reaction of 1,1,1-trihalo-4-alkoxy-3-alken-2-ones with hydroxylamine and anilines, respectively, using water as solvent and under ultrasound irradiation is reported. 相似文献