Indium metal as a reducing agent. Selective reduction of the carbon-carbon double bond in highly activated conjugated alkenes

[reaction: see text] Indium metal in aqueous ethanolic ammonium chloride reduces the C=C bond in highly activated conjugated alkenes such as alpha,alpha-dicyano olefins, beta-arylenones, and enone esters.     

An elementary proof of the restricted invertibility theorem

We give an elementary proof of a generalization of Bourgain and Tzafriri’s Restricted Invertibility Theorem, which says roughly that any matrix with columns of unit length and bounded operator norm has a large coordinate subspace on which it is well-invertible. Our proof gives the tightest known form of this result, is constructive, and provides a deterministic polynomial time algorithm for finding the desired subspace.     

Semidefinite optimization in discrepancy theory

Recently, there have been several new developments in discrepancy theory based on connections to semidefinite programming. This connection has been useful in several ways. It gives efficient polynomial time algorithms for several problems for which only non-constructive results were previously known. It also leads to several new structural results in discrepancy itself, such as tightness of the so-called determinant lower bound, improved bounds on the discrepancy of the union of set systems and so on. We will give a brief survey of these results, focussing on the main ideas and the techniques involved.     

Dense wavelength division demultiplexing using photonic crystal waveguides based on cavity resonance

We demonstrated a photonic crystal waveguide based dense wavelength division multiplexing device using the resonances in the cavities. The demultiplexing is achieved through filtering. This filtering is achieved by varying the radii of the surrounding holes of the cavity, which in turn changes the resonant wavelength of the cavity. The four wavelengths demultiplexed in the design are 0.8 nm apart in the optical region centered on 1.55 and 1.56 μm. The device designed and simulated has easy to realize structure as well as high quality factor. Two-dimensional Finite Difference Time Domain (FDTD) is chosen to do the simulation of this work.     

Carbon nanofiber reinforced syntactic foams: Degradation mechanism for long term moisture exposure and residual compressive properties

Hollow particle filled polymer matrix composites, called syntactic foams, are challenging for studies related to environmental exposure and degradation mechanisms due to the possible role of matrix, particle–matrix interface, and particle material and wall thickness. In the current study, syntactic foams reinforced with 1 wt.% vapor grown carbon nanofibers (CNFs) are subjected to water immersion and characterized for residual compressive properties under quasi-static and high strain rates. The testing is conducted on four different types of syntactic foams, fabricated with glass hollow particles of two different densities: 220 and 460 kg/m³ in 30 and 50 vol.% quantities. After a period of 6 months, a maximum of 7% weight gain is observed in the worst performing syntactic foam. The exposed specimens are tested for residual compressive properties and the results are compared with the properties of dry specimens. The quasi-static compressive strength of CNF reinforced syntactic foams is found to decrease and the modulus remained unaffected due to the moisture exposure. The high strain rate compressive strength was 1.3–2.2 times higher for wet and dry specimens compared to the quasi-static strength of the same type of syntactic foams.     

Efficient,Three-Component Synthesis of Pyrrole Derivatives Catalyzed by Iodobenzene and Oxone

A simple and highly efficient three-component method using easily available amines, nitrostyrene, and diketones in one pot has been developed for synthesis of pyrroles in the presence of catalytic amounts of iodobenzene and Oxone as oxidant. The protocol has been used to afford wide range of pyrroles in moderate to good yields.     

Novel and cost‐effective 6‐plex isobaric tagging reagent,DiART, is effective for identification and relative quantification of complex protein mixtures using PQD fragmentation

Deuterium isobaric Amine Reactive Tag (DiART) reagents facilitate relative quantification during proteomic analysis in a functionally similar manner to commercially available isobaric tag for relative and absolute quantitation (iTRAQ) and tandem mass tag (TMT) reagents. In contrast to iTRAQ and TMT, DiART reagents incorporate deuterium isotopes which significantly reduce the number of required synthesis steps and hence have potential to significantly reduce reagent production cost. We examined the capability of DiART for performing quantitative proteomic experiments using a linear ion‐trap mass spectrometer with Pulsed Q Dissociation (PQD) fragmentation. Using a synthetic peptide tagged with DiART reagent, we observed a precise mass shift of 144.79 Da on the triply charged precursor ion, which shows complete derivatization of the N‐terminus and ε‐amino group of lysine. A DiART tagged tryptic digest of bovine serum albumin showed a sequence coverage of 57.99% which was very comparable to that showed by iTRAQ, 54.77%. Furthermore, a ten protein mixture tagged with DiART reagents and mixed in 1:1:1:1:1:1 exhibited < 15% error, whereas a linear trend (slope of 1.085) was observed when tagged proteins were mixed in the ratio 2:1:2:4:10:14 and plotted against theoretical ratios. Finally, when complex cell‐wall protein mixtures from the model fungus A. nidulans were tagged with DiART reagents and mixed in different ratios, they exhibited similar trends. We conclude that DiART reagents are capable of performing quantitative proteomic experiments using PQD on a linear ion trap mass spectrometer. Copyright © 2013 John Wiley & Sons, Ltd.