CoI-Catalyzed Barbier Reactions of Aromatic Halides with Aromatic Aldehydes and Imines

The reductive Barbier coupling of aromatic halides and electrophiles has been achieved using a CoBr₂/1,10-phenanthroline catalytic system and over stoichiometric amounts of zinc. The reaction displayed a broad scope of substrates, including (hetero)aryl chlorides as pro-nucleophiles and aldehydes or imines as electrophiles, leading to diarylmethanols and diarylmethylamines in moderate to excellent yields, respectively.     

On Quantized Decomposition Maps for Graded Algebras

Decomposition maps control the representation theory of algebras obtained through the process of specialization. In this note, we study a factorization result for graded decomposition maps associated with the specializations of graded algebras. We obtain results previously known only in the ungraded setting.     

Large‐Scale Synthesis of Enantiopure Molecular Cages: Chiroptical and Recognition Properties

A convenient and efficient gram‐scale synthesis for enantiopure hemicryptophane–tren (tren=tris(2‐aminoethyl)amine) derivatives has been developed. The four‐step synthesis is based on the optical resolution of a key intermediate, cyclotriveratrylene, for which the energy barrier for racemization has been measured to ensure that no racemization occurs during the two last steps of the synthetic pathway. The assignments of the absolute configurations have been performed by electronic circular dichroism and the enantiopurity was determined by NMR spectroscopy in the presence of enantiopure camphor sulfonic acid. To highlight the interest of such compounds, the recognition of norephedrine neurotransmitter was investigated and showed a remarkable enantioselectivity towards the C₃ symmetrical hosts. Finally, this highly modular synthetic pathway was used to provide eight enantiopure hemicryptophanes with different sizes, shapes, and functionalities. These results underline the high potential of this approach, which could lead to many applications in chiral recognition or asymmetric supramolecular catalysis.     

Distortion Correction Protocol for Digital Image Correlation after Scanning Electron Microscopy: Emphasis on Long Duration and Ex-Situ Experiments

Recently, scanning electron microscopy (SEM) has been used for digital image correlation (DIC), as micrographs can be acquired with high magnification, providing improved resolution to quantify strain heterogeneities. However, it has been shown by researchers that SEM images can be problematic due to inherent electromagnetic distortions that are not present in optical images. Drift, spatial distortions, and magnification uncertainties are the main issues that can seriously affect the accuracy of localized strain measurements. The present work focuses on long duration experiments, for which images are taken days or weeks apart. We have proposed a systematic procedure to reduce drift, correct spatial distortion, and account for magnification variations between pairs of acquired images. Additionally, SEM parameters are discussed and chosen to increase the signal-to-noise ratio and improve the accuracy of the DIC measurements. The spatial distortion correction increases the repeatability of the correlated values and the precision of the measurements. The implementation for this type of correction is done by applying the measured distortion gradient of a certified grid onto the DIC strain field. The magnification adjustment increases the reliability of the strain maps, ensuring the measurements are in agreement with the actual strain induced during the experiment. We have presented a systematic protocol for ex-situ DIC experiments within the SEM and some basic cross-check procedures that can be performed to evaluate the reliability of the reference grid and the precision of the final strain map.