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121.
122.
Jan K. Baeke Roeland De Borger Filip Lemière Christian Van Alsenoy Frank Blockhuys 《Journal of Physical Organic Chemistry》2009,22(10):925-932
A novel class of self‐doping conjugated oligomers, E,E‐2‐(sulfoalkoxy)‐5‐alkoxy‐1,4‐bis[2‐(2,4,6‐trimethoxyphenyl) ethenyl]benzenes, is presented. The synthesis and spectroscopic characterisation of five such oligomers are described, and an electrochemical analysis using cyclic voltammetry is performed to determine the anodic peak potentials. A structural study is performed on six self‐doping oligomers in which the structures and energies of the possible mono‐molecular forms of the electrically conducting doped material are described and evaluated using Hirshfeld charges and the Quantum Theory of Atoms In Molecules. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
123.
Nicola Pizzolato Davide Valenti Dominique Persano Adorno Bernardo Spagnolo 《Central European Journal of Physics》2009,7(3):541-548
The evolutionary dynamics of a system of cancerous cells in a model of chronic myeloid leukemia (CML) is investigated by a
statistical approach. Cancer progression is explored by applying a Monte Carlo method to simulate the stochastic behavior
of cell reproduction and death in a population of blood cells which can experience genetic mutations. In CML front line therapy
is represented by the tyrosine kinase inhibitor imatinib which strongly affects the reproduction of leukemic cells only. In
this work, we analyze the effects of a targeted therapy on the evolutionary dynamics of normal, first-mutant and cancerous
cell populations. Several scenarios of the evolutionary dynamics of imatinib-treated leukemic cells are described as a consequence
of the efficacy of the different modelled therapies. We show how the patient response to the therapy changes when a high value
of the mutation rate from healthy to cancerous cells is present. Our results are in agreement with clinical observations.
Unfortunately, development of resistance to imatinib is observed in a fraction of patients, whose blood cells are characterized
by an increasing number of genetic alterations. We find that the occurrence of resistance to the therapy can be related to
a progressive increase of deleterious mutations.
相似文献
124.
S. Gleyzes A. El Amili R. A. Cornelussen P. Lalanne C. I. Westbrook A. Aspect J. Estève G. Moreau A. Martinez X. Lafosse L. Ferlazzo J. C. Harmand D. Mailly A. Ramdane 《The European Physical Journal D - Atomic, Molecular, Optical and Plasma Physics》2009,53(1):107-111
We study a Fabry-Perot cavity formed from a ridge waveguide on a AlGaAs substrate. We experimentally determined the propagation
losses in the waveguide at 780 nm, the wavelength of Rb atoms. We have also made a numerical and analytical estimate of the
losses induced by the presence of the gap which would allow the interaction of cold atoms with the cavity field. We found
that the intrinsic finesse of the gapped cavity can be on the order of F∼30, which, when one takes into account the losses
due to mirror transmission, corresponds to a cooperativity parameter for our system C∼1. 相似文献
125.
We define new tilings of the plane with Robinson triangles, by means of generalized inflation rules, and study their Fourier spectrum. Penrose's matching rules are not obeyed; hence the tilings exhibit new local environments, such as three different bond lengths, as well as new patterns at all length scales. Several kinds of such generalized tilings are considered. A large class of deterministic tilings, including chiral tilings, is strictly quasiperiodic, with a tenfold rotationally symmetric Fourier spectrum. Random tilings, either locally (with extensive entropy) or globally random (without extensive entropy), exhibit a mixed (discrete+continuous) diffraction spectrum, implying a partial perfect long-range order. 相似文献
126.
S. De Nicola A. E. Kaplan S. Martellucci P. Mormile G. Pierattini J. Quartieri 《Applied physics. B, Lasers and optics》1989,49(5):441-444
We have observed a hysteretic (bistable) reflection of a Gaussian laser beam at the interface between glass and a liquid solution of polystyrene microspheres as nonlinear medium with both branches of the hysteretic curve being stable, in contrast to the results of previous experiments. 相似文献
127.
A recent paper of Capone et al. has studied an extended Hubbard model, in which local orbital degrees of freedom allow an even integer occupation at each site. A strong local repulsion U triggers a metal-insulator transition. Within a DMFT numerical analysis they show that when the ground state is a singlet a pocket of s-wave superconductivity appears in the vicinity of the Mott transition, with a strongly enhanced superconducting gap. A qualitative understanding of their result is proposed, and suggestions are made of possible systems in which this beautiful effect might be searched. 相似文献
128.
We show that frequency and intensity noise in a Nd:YAG laser are correlated to a high degree and can be traced to the same underlying cause, namely, power fluctuations of the pump source. Because of this correlation, simultaneous suppression of frequency and intensity noise by 30 dB is achieved by means of a single actuator, the pump power. 相似文献
129.
Hoang GT Bourdelle C Garbet X Artaud JF Basiuk V Bucalossi J Clairet F Fenzi-Bonizec C Gil C Ségui JL Travère JM Tsitrone E Vermare L 《Physical review letters》2004,93(13):135003
Steady state full noninductive current tore supra plasmas offer a unique opportunity to study the local parametric dependence of particle pinch velocity, in order to discriminate among different theories. Magnetic field shear is found to generate an inward pinch which is dominant in the gradient region (normalized radius 0.3=r/a=0.6). In contrast, the direction of the pinch in the plasma core (r/a=0.3) is correlated with the electron temperature gradient length. The results are in agreement with both the turbulent theoretical and computational predictions. 相似文献
130.
Laveissière G Todor L Degrande N Jaminion S Jutier C Di Salvo R Van Hoorebeke L Alexa LC Anderson BD Aniol KA Arundell K Audit G Auerbach L Baker FT Baylac M Berthot J Bertin PY Bertozzi W Bimbot L Boeglin WU Brash EJ Breton V Breuer H Burtin E Calarco JR Cardman LS Cavata C Chang CC Chen JP Chudakov E Cisbani E Dale DS de Jager CW De Leo R Deur A d'Hose N Dodge GE Domingo JJ Elouadrhiri L Epstein MB Ewell LA Finn JM Fissum KG Fonvieille H Fournier G Frois B Frullani S Furget C Gao H Gao J 《Physical review letters》2004,93(12):122001
We report a virtual Compton scattering study of the proton at low c.m. energies. We have determined the structure functions P(LL)-P(TT)/epsilon and P(LT), and the electric and magnetic generalized polarizabilities (GPs) alpha(E)(Q2) and beta(M)(Q2) at momentum transfer Q(2)=0.92 and 1.76 GeV2. The electric GP shows a strong falloff with Q2, and its global behavior does not follow a simple dipole form. The magnetic GP shows a rise and then a falloff; this can be interpreted as the dominance of a long-distance diamagnetic pion cloud at low Q2, compensated at higher Q2 by a paramagnetic contribution from piN intermediate states. 相似文献