A Classical Cosmological Model for Triviality

The aim of this paper is to study the triviality of λ ϕ⁴ theory in a classical gravitational model. Starting from a conformal invariant scalar tensor theory with a self-interaction term λ ϕ⁴, we investigate the effect of a conformal symmetry breaking emerging from the gravitational coupling of the large-scale distribution of matter in the universe. Taking in this cosmological symmetry breaking phase the infinite limit of the maximal length (the size of the universe) and the zero limit of the minimal length (the Planck length) implies triviality, i.e. a vanishing coupling constant λ. It suggests that the activity of the self-interaction term λ ϕ⁴ in the cosmological context implies that the universe is finite and a minimal fundamental length exists.     

Numerical Simulation of Forced Convective Heat Transfer Past a Square Diamond-Shaped Porous Cylinder

Fluid flow and heat transfer around and through a porous cylinder is an important issue in engineering applications. In this paper a numerical study is carried out for simulating the fluid flow and forced convection heat transfer around and through a square diamond-shaped porous cylinder. The flow is two-dimensional, steady, and laminar. Conservation laws of mass, momentum, and heat transport equations are applied in the clear region and Darcy–Brinkman–Forchheimer model for simulating the flow in the porous medium has been used. Equations with the relevant boundary conditions are numerically solved using a finite volume approach. In this study, Reynolds and Darcy numbers are varied within the ranges of $1<Re<45$ and $10^{-6}<Da<10^{- 2}$ , respectively. The porosity $(\varepsilon )$ is 0.5. This paper presents the effect of Reynolds and Darcy numbers on the flow structure and heat transfer characteristics. Finally, these parameters are compared among solid and porous cylinder. It was found that the drag coefficient decreases and flow separation from the cylinder is delayed with increasing Darcy number. Also the size of the thermal plume decreases by decreasing Darcy number.     

Analytical Solutions to Gas Flow Problems in Low Permeability Porous Media

In most of conventional porous media the flow of gas is basically controlled by the permeability and the contribution of gas flow due to gas diffusion is ignored. The diffusion effect may have significant impact on gas flow behavior, especially in low permeability porous media. In this study, a dual mechanism based on Darcy flow as well as diffusion is presented for the gas flow in homogeneous porous media. Then, a novel form of pseudo pressure function was defined. This study presents a set of novel analytical solutions developed for analyzing steady-state and transient gas flow through porous media including effective diffusion. The analytical solutions are obtained using the real gas pseudo pressure function that incorporates the effective diffusion. Furthermore, the conventional assumption was used for linearizing the gas flow equation. As application examples, the new analytical solutions have been used to design new laboratory and field testing method to determine the porous media parameters. The proposed laboratory analysis method is also used to analyze data from steady-state flow tests of three core plugs. Then, permeability (k) and effective diffusion coefficient (D _e) was determined; however, the new method allows one to analyze data from both transient and steady-state tests in various flow geometries.     

Electron delocalization and aromaticity variations in the stacked nucleic acid base pairs

A newly developed exchange-correlation functional (MPWB1K) in density functional theory has been applied to evaluate the electron delocalization of individual fragments in the stacking interaction between nucleic acid bases (NABs). Electronically and structural-based indices have been employed to investigate the aromaticity variation during stacking interaction. A quantitative study of NABs in their isolated and stacked forms reveals that stacking interaction causes a decrease in bond delocalization. It is shown that the decrease in the aromaticity is accompanied by local decrease in two-center delocalization indices within the pyrimidine rings. We found that the aromaticity exhibits a similar trend for NABs in both their isolated and stacked forms. Moreover, it is indicated that aromatic fluctuation index is more sensible index to delineate the aromaticity variation during stacking interaction.

     

Inhibitory effects of Ruta graveolens L. extract on guinea pig liver aldehyde oxidase

Ruta graveolens L. is a flavonoid-containing medicinal plant with various biological properties. In the present study, the effects of R. graveolens extract on aldehyde oxidase, a molybdenum hydroxylase, are investigated. Aldehyde oxidase was partially purified from liver homogenates of mature male guinea pigs by heat treatment and ammonium sulphate precipitation. The total extract was obtained by macerating the aerial parts of R. graveolens in MeOH 70% and the effect of this extract on the enzyme activity was assayed using phenanthridine, vanillin and benzaldehyde as substrates. Quercetin and its glycoside form, rutin were isolated, purified and identified from the extract and their inhibitory effects on the enzyme were investigated. R. graveolens extract exhibited a high inhibition on aldehyde oxidase activity (89-96%) at 100 microg/ml which was comparable with 10 microM of menadione, a specific potent inhibitor of aldehyde oxidase. The IC50 values for the inhibitory effect of extract against the oxidation of benzaldehyde, vanillin and phenanthridine were 10.4, 10.1, 43.2 microg/ml, respectively. Both quercetin and rutin at 10 microM caused 70-96% and 27-52% inhibition on the enzyme activity, respectively. Quercetin was more potent inhibitor than rutin, but both flavonols exerted their inhibitory effects mostly in a linear mixed-type.     

A review on potentials of coupling PCM storage modules to heat pipes and heat pumps

Journal of Thermal Analysis and Calorimetry - A large portion of world’s final energy consumption is employed in thermal form. The proper techniques can be used to improve the efficiencies of...     

Design and synthesis of new 2-substituted-5-[2-(2-halobenzyloxy)phenyl]-1,3,4-oxadiazoles as anticonvulsant agents

A new series of 2-substituted-5-[2-(2-halobenzyloxy)phenyl]-1,3,4-oxadiazoles was designed and synthesized as anticonvulsant agents. Electroshock and pentylenetetrazole-induced lethal convulsion tests showed that the introduction of an amino group at position 2 of 1,3,4-oxadiazole ring and a fluoro substituent at ortho position of benzyloxy moiety had the best anticonvulsant activity. Our results showed that this effect is mediated through benzodiazepine receptors mechanism.     

Viscoelastic fluid behavior in annulus using Giesekus model

An analytical solution is derived for the steady state, laminar, axial, fully developed flow of a viscoelastic fluid obeying the Giesekus model without any retardation time in a concentric annulus.An approximation is used for the estimation of radial normal stress. The influence of Deborah number (De) and the mobility factor (α) on the velocity profile, axial pressure gradient are investigated and results show strong effects of mobility factor and Deborah number on above parameters.     

Vitamin B12 supported on graphene oxide: As a bio‐based catalyst for selective aerobic oxidation of alcohols

The environmental impact of chemical processes has now opened new windows of opportunity for bio‐based catalysts. In this paper a highly active bio‐based catalyst of vitamin B₁₂ supported on graphene oxide nanosheets is reported for the selective aerobic oxidation of alcohols to the corresponding carbonyl compounds. Operational simplicity, mild reaction conditions, high yield and selectivity, non‐hazardous nature, commercial availability and affordability are the main advantages of this novel catalytic system.     

Direct C2-arylation of quinoline N-oxides by boronic esters; a molecular approach on the efficient metal-free method in C–C cross-coupling reactions

Research on Chemical Intermediates - Kinetic and thermodynamic aspects of the cross-coupling reaction of quinoline N-oxides by various boronic esters in the gas and solvent phases were...