Mechanistic Insights into the Self-Assembly of an Acid-Sensitive Photoresponsive Supramolecular Polymer

The supramolecular polymerization of an acid-sensitive pyridyl-based ligand ( L₁ ) bearing a photoresponsive azobenzene moiety was elucidated by mechanistic studies. Addition of trifluoroacetic acid (TFA) led to the transformation of the antiparallel H-bonded fibers of L₁ in methylcyclohexane into superhelical braid-like fibers stabilized by H-bonding of parallel-stacked monomer units. Interestingly, L₁ dimers held together by unconventional pyridine–TFA N⋅⋅⋅H⋅⋅⋅O bridges represent the main structural elements of the assembly. UV-light irradiation caused a strain-driven disassembly and subsequent aggregate reconstruction, which ultimately led to short fibers. The results allowed to understand the mechanism of mutual influence of acid and light stimuli on supramolecular polymerization processes, thus opening up new possibilities to design advanced stimuli-triggered supramolecular systems.     

New approach for fractional Schrödinger-Boussinesq equations with Mittag-Leffler kernel

In this paper, we find the solution and analyse the behaviour of the obtained results for the nonlinear Schrödinger-Boussinesq equations using q -homotopy analysis transform method (q -HATM) within the frame of fractional order. The considered system describes the interfaces between intermediate long and short waves. The projected fractional operator is proposed with the help of Mittag-Leffler function to incorporate the nonsingular kernel to the system. The projected algorithm is a modified and accurate method with the help of Laplace transform. The convergence analysis is presented with the help of the fixed point theorem in the form existence and uniqueness. To validate and illustrate the effectiveness of the algorithm considered, we exemplified considered system with respect of arbitrary order. Further, the behaviour of achieved results is captured in contour and 3D plots for distinct arbitrary order. The results show that the projected scheme is very effective, highly methodical and easy to apply for complex and nonlinear systems and help us to captured associated behaviour diverse classes of the phenomenon.     

A class of upwind methods based on generalized eigenvectors for weakly hyperbolic systems

Numerical Algorithms - In this article, a class of upwind schemes is proposed for systems, each of which yields an incomplete set of linearly independent eigenvectors. The theory of Jordan...     

A stereoselective synthesis of the hexahydroazepine core of (−)-balanol

A stereoselective synthesis of the hexahydroazepine core of (−)-balanol is described. The key step of the route includes the bromosulfonamidation of an olefin using the intramolecular sulfilimine group as the nucleophile and the Pummerer ene reaction.     

Sulfinyl group as an intramolecular nucleophile: synthesis of bromohydrins from beta-methyl-gamma,delta-unsaturated sulfoxides with high 1,2-asymmetric induction

Bromohydrins have been prepared from beta-methyl-gamma,delta-unsaturated sulfoxides with high regio- and stereoselectivity. The reaction proceeds via neighboring group participation of the sulfinyl moiety with inversion of sulfoxide configuration as proven by an (18)O labeling study and X-ray crystallography.     

Log-polar transform-based wavelet-modified maximum average correlation height filter for distortion-invariant target recognition

In this paper, we report a log-polar transform-based filter for in-plane rotation and scale-invariant target recognition. The log-polar transform is a known space-invariant image representation used in several image vision systems to eliminate the effects of scale and rotation in an image. In case of in-plane rotation invariance, peaks shift horizontally, while in case of scale invariance, peaks shift vertically. For full out-of-plane rotation-invariance (0–360°), log-polar transformed images are used to train the wavelet-modified maximum average correlation height (WaveMACH) filter. Correlation peak height and peak-to-sidelobe ratio have been calculated as metrics of goodness of the log-polar transform-based WaveMACH filter. This filter would reduce the memory requirement for filter storage in a practical system. Simulation results have been presented.     

Development of Transition-Metal-Free Lewis Acid-Initiated Double Arylation of Aldehyde: A Facile Approach Towards the Total Synthesis of Anti-Breast-Cancer Agent

This work describes a mild and robust double hydroarylation strategy for the synthesis of symmetrical /unsymmetrical diaryl- and triarylmethanes in excellent yields using Lambert salt (0.2–1.0 mol%). Despite the anticipated challenges associated with controlling selective product formation, unsymmetrical diaryl- and triarylmethanes products are obtained unprecedentedly. A highly efficient gram scale reaction has also been reported (TON for symmetrical product=475 and for unsymmetrical product=390). The synthetic utility of the methodology is demonstrated by the preparation of several unexplored diaryl- and triarylmethane-based biologically relevant molecules, such as arundine, vibrindole A, turbomycin B, and certain anti-inflammatory agents. A total synthesis of an anti-breast-cancer agent is also demonstrated. Control experiments, Hammett analysis, HRMS and GC-MS studies reveal the reaction intermediates and reaction mechanism.     

Brookhart's Acid-Catalyzed Switchable Regioselective N-Alkylation of Arylamines/Heterocyclic Amines with Cyclopropylcarbinols by Temperature Regulation

An unprecedented, Brookhart's acid-catalyzed temperature-switchable regioselective divergent approach for N-alkylation of arylamines and heterocyclic amines by utilising cyclopropylcarbinols is presented herein. The reaction offers N-alkylated cyclopropyl derivatives and homoallyl amines by employing 2.5 mol% catalyst loading at different temperatures in excellent regioselectivity and yields. This method has shown to be relevant with a wide range of cyclopropylcarbinols, including aliphatic ones. Several control experiments and spectroscopic studies have been performed to gain insight into the reaction mechanism. Further, the synthetic utility of the protocol has also been described.