Protein Folding and β‐Sheet Proteins

The aim of this comprehensive review is to critically evaluate the progress in research in the area of protein folding. In the first section, we discuss the various models proposed to explain the protein folding paradox. In the succeeding section of the review, a detailed account of the developments in our understanding of the folding path ways of β‐sheet proteins is provided.     

Satellites,hypersatellites and RAE from Ti,V, Cr,Mn and Fe in photoionisation

K x‐ray satellites, hypersatellites and lines due to radiative Auger effect (RAE) of Ti, V, Cr, Mn and Fe were measured after exciting the samples with Ag bremsstrahlung at 35 kV. All the lines were measured with the ‘Spectroscan VY’ spectrometer of Spectron—OPTEL, Russia, in which a curved LiF(200) crystal was used. The spectra were deconvoluted using Voigt functions, and the peak positions of the satellites and hypersatellites were determined with errors of ± (1–5) eV. The energy shifts of the satellite lines with respect to their parent lines were also obtained. Multi‐configuration Dirac–Fock (MCDF) calculations with the inclusion of higher‐order corrections were carried out to predict the peak positions of the satellite and hypersatellite lines. Our data were then compared with our own calculated values and also with the data of others. Our measured energy shifts for K_αL¹, K_αL², K_α^h and K_βL¹, when compared with our MCDF calculations, show a maximum deviation of 8, 12, 2 and 20% respectively. Copyright © 2008 John Wiley & Sons, Ltd.     

Study of EIT resonances in an anti-relaxation coated Rb vapor cell

We study the sign of resonances obtained in electromagnetically induced transparency (EIT). Resonances of both kinds—bright (corresponding to enhanced absorption) and dark (corresponding to reduced absorption)—are obtained when the frequency of a probe beam is scanned. The experimental results, presented earlier, use magnetic sublevels of a hyperfine transition in the D₁ line of ⁸⁷Rb along with a magnetic field of 27 G. The atoms are contained in a vapor cell at room temperature, and with anti-relaxation coating on the walls. A quantitative theoretical model, which reproduces the experimental results quite well, is presented for the first time. The model solves the density matrix of the sublevels involved, and uses two regions—one with both the light and magnetic field, and the second without light and just a magnetic field. This ability to have both bright and dark resonances promises applications in sub- and super-luminal propagation of light.     

The Inverse Gaussian Models: Analogues of Symmetry, Skewness and Kurtosis

The inverse Gaussian (IG) family is strikingly analogous to the Gaussian family in terms of having simple inference solutions, which use the familiar ², t and F distributions, for a variety of basic problems. Hence, the IG family, consisting of asymmetric distributions is widely used for modelling and analyzing nonnegative skew data. However, the process lacks measures of model appropriateness corresponding to and ₂, routinely employed in statistical analyses. We use known similarities between the two families to define a concept termed IG-symmetry, an analogue of the symmetry, and to develop IG-analogues ₁ and ₂ of and ₂, respectively. Interestingly, the asymptotic null distributions of the sample versions d ₁, d ₂ of ₁, ₂ are exactly the same as those of their normal counterparts and b ₂. Some applications are discussed, and the analogies between the two families, enhanced during this study are tabulated.     

Synthesis and spectral studies of cobalt(II), nickel(II) and copper(II) complexes of 1-(2-hydroxy-1-naphthyl)-3-(4-X-phenyl)-2-propen-1-ones and their pyridine adducts

Transition Metal Chemistry - Metal(II) chelates of the type ML2nB [M = CoII, NiII and CuII; L = 1-(2-hydroxy-1-naphthyl)-3-(4-X-phenyl)-2-pro-pen-1-one, (X = H, Cl or Me); B = H2O or Py; n = 0, 2]...     

Studies on the mixing of two non-axial jets in a confined passage — turbulence characteristics

The mean characteristics of the flow due to mixing of two non-axial plane jets in a confined passage, were reported previously by Manjunath et al. (Exp. Fluids 11 (1991), 17–24), as part I. In this paper, the turbulence characteristics of the flow are discussed. The various components of the Reynolds stress tensor are reported for the four inlet angles considered, viz., 15°, 30°, 45° and 60°. As expected from the mean flow field, the inlet angle influences the distribution of the various turbulence components through the relative size of the recirculation zones and the turbulence field is different for the smaller angles of 15° and 30° in comparison to those for 45° and 60°.     

Determination of Cd, Co, Cu, Fe and Ni at parts per billion level in high-purity gallium by graphite furnace atomic absorption spectrometry (GFAAS)

Summary The determination of Cd, Co, Cu, Fe and Ni in 6N gallium by GFAAS is reported. The analytes are extracted as pyrrolidine dithiocarbamates into methyl-iso-butyl-ketone (MIBK) in the presence of tartrate. The conditions of extraction, quantity of reagents required and the matrix interference aspects are discussed. The method offers one-step matrix removal and preconcentration, leading to low experimental blanks.