3α-氨基-2β,17β-二羟基-16β-哌啶基-5α-雄甾烷和2β-氨基-3α,17β-二羟基-16β-哌啶基-5α-雄甾烷的合成

1975年Varg ftig等发现,3α-氨基-2β-羟基-5α-雄甾-17-酮盐酸盐(Org 6001)具有抗心律失常作用,它不仅口服有效,疗效优于利多卡因,而且无激素活性,被认为是一类新型结构的抗心律失常药。以后,人们又对Org 6001进行了一系列的结构改造工作,但     

OXIDATION DECARBONYLATION OF NH_4[Mo(CO)_5I]: SYNTHE-SES AND CRYSTAL STRUCTURES OF CMo(S_2CNC_4H_8)_4]I_3 · C_7H_8 and Mo_2S_2O_2(S_2CNC4H_8)_2

<正> Both of the title complexes were produced by oxidative decarbony-lation of NH4 CMO (CO)5I]. The complexes CMo(S2CNC4H8)4]I3 ?C7H8(1) and Mo2S2O2 (S2CNC4H8)2(2) both crystallize in triclinic, space group P1 with cell dimensions for (1) : a=13. 554(4), b=13. 620(4), c= 13. 058 (4) A , α=95. 58 (3), β=105. 38(2), γ=115. 49(2)°,V = 2035(1) A3, Z=2, Dc=1. 89 g. cm-3, final R=0. 054 and Rw = 0. 062 for 2926 observed reflections; and for (2): a = 8.730(2), b=16.592(6), c = 6. 688(2)A, α=97. 67(3), β=98. 10(2), γ=80. 26(2)% V = 939. 2(5) A3, Z = 2, Dc = 2. 05 g. cm-3, final R = 0. 038 and Rw = 0. 046 for 2248 observed reflections. The Mo(V) atom is bonded to eight S atoms in distorted dodecahedron for (1). The Mo atoms in compound (2) are bridged by two S atoms and each Mo atom is coordinated by two S atoms from S2CNC4H8 and one O atom to form distorted tetragonal pyramid.     

含DMIT配体配合物的结构与导电性

本文描述了含DMIT(4,5-二硫基-1,3-二硫杂环戊烯-2-硫酮)配体配合物的含成和导电性,讨论了其各个结构层次及其与导电性的关系。Ni、Pd、Pt、的DMIT导电配合物的分子结构特征是平面构型和离域π电子态,晶体结构特征是配位阴离子堆砌成各种形式的、导电能力不同的分子柱和分子层,作为非导电组元的平衡离子对导电性也有重要影响。     

催化极谱法测定痕量铬的研究

本文研究了含氨介质中铬(Ⅲ、Ⅵ)-α,α’-联吡啶-亚硝酸钠体系的电化学行为。建立了测定痕最铬的方法。测定铬的范围为0.004～0.028μg/mL和0.04～0.23μg/mL,检测下限为2.0×10~(-3)μg/mL,用以测定生物样品中良量铬,变异系数为0.8%。     

手性膦过渡金属配合物催化不对称交叉偶联反应的研究

自1973年Consiglio和Botteghi首次报道用(一)-DIOP的NiCl_2配合物催化芳基或乙烯基卤代物与仲烷基卤化镁交叉偶联生成光学活性的偶联产物以来,化学家们对不对称交叉偶联反应进行了深入研究。Hayashi等用手性二茂铁膦和手性β-氨基烷基膦的NiCl_2和PdCl_2配合物催化1-苯基乙基氯化     

A new class of rhodium complexes containing free donor atoms and their intramolecular substitution reaction

A new class of rhodium complexes with high catalytic activity as well as excellent stability,which was used as catalyst for carbonylation of methanol to acetic acid,is reported.It contains free donor (namely un-coordinated donor) atoms which enable to improve its stability by intramolecular substitution reaction.Its synthesis,characteristic and catalytic reaction were discussed here.     

PREPARATION AND THEIR ANTIBACTERIAL ACTIVITY OF ACTIVATED CARBON FIBER CONTAINING SILVER*

1.INTRODUCTIONActivatedcarbonfibers(ACF)havehighspecificsurfaceareasorabundantmicropores,whichmakethemhavegreatadsorptionrateandlargeadsorptioncapacity.Nowtheymakeaveryimportantroleinenvironmentalcontrolandinresourcerecovery[1].Bytakingadvantageoftheactivatedcarbonfibers'adsorptionabilityagainstbacteriaandstenchsubstance,theycanalsobeusedinpurifyingblood,inmedicinebandageforpreventingthewoundbacteriafrompropagatingandforadsorbingandeliminatingthewoundstench.Theresultsbyotherworkersindica…     

Recent advances in spin transport in organic semiconductors

The spin relaxation time is long in organic semiconductors because of the weak spin-orbit and hyperfine interactions,leading to intensive study on spin transport in organic semiconductors.The rapid progress towards utilizing spin degree of freedom in organic electronic devices is occurring.While the spin injection,transport and detection in organic semiconductors are demonstrated,the fundamental physics of these phenomena remains unclear.This paper highlights recent progress that has been made,focusing primarily on present experimental work.     

利用清洁工艺生产柠檬酸的研究

本文设计了一条生产柠檬酸的新工艺，可望有效的解决柠檬酸生产中的环境污染问题，并对生产过程中所产生的化合物的再次利用提出了新的方法，实验结果表明，利用该工艺生产柠檬酸，其收率可从传统的80％提高到89％，产生的污染物可下降80％以上。