Molecular Spectroscopic Study on the Interaction between Heparin and Neutral Red

The interaction between heparin and neutral red was investigated by molecular spectroscopic methods. The change of all spectra suggested that positively charged neutral red had interacted with negatively charged heparin. The study of influence factors indicated that electrostatic force and hydrophobic bond might be involved in the interaction. The total binding number per disaccharide unit and intrinsic binding constant were obtained using Scatchard model.     

A Novel Green Preparation of a, a''''-Bis (substituted benzylidene)-cycloalkanones Promoted by FeCl_3 6H-2O in Ionic Liquid

a, a'-Bis(substituted benzylidene)cycloalkanones were efficiently prepared from cycloalkanones and benzaldehydes in [bmim][BF4] by using iron(III) chloride hexahydrate as a catalyst. It is shown that [bmim][BF4] and iron(III) chloride hexahydrate can be quantitatively recovered and be reused effectively for many times. Compared with the known methods, this novel process has the advantage of being an envkonmentally benign process together with good yields and mild reaction conditions.     

Structure of Tetra[β-(1,2,4-triazole-1-yl)propiophenone] Dichloro Nickel(II) Solvate Hexahydrate Complex: [NiCl_2(C_2H_2N_3CH_2CH_2COPh)_4]·6H_2O

IntroductionRecently ,thecompoundscontaining 1H 1,2 ,4 tria zolegrouphaveattractedmuchinterestbecausetheyex hibitsomefungicidalactivity ,plantgrowthregulatingac tivity ,1antibacterialactivityagainstPucciniareconditeandrootsgrowthregulationforcucumber .2 Also ,suchcom poundsareincreasinglybeingstudiedbecauseofthecoor dinationchemistryoftriazolesactingasligandsintransi tionmetalcompounds .Asamatteroffact ,thetriazolederivativeshavebeenextensivelyusedasterminalandbridgingligands ,andtheyleadto…     

酚醛型吸附树脂对水体系中吡啶和N,N-二甲基苯胺的吸附性能研究

研究了酚醛型吸附树脂在水体系中对吡啶和N，N-二甲基苯胺的静态和动态吸附行为．结果表明，在水中树脂对吡啶和N，N-二甲基苯胺的吸附主要以疏水吸附机理进行；吸附吡啶和N．N-二甲基苯胺的初始阶段，即达到38．3～48．9％平衡吸附时，吸附速率数据和半经验速率方程很吻合：酚醛型吸附树脂等温吸附吡啶和N，N-二甲基苯胺的平衡吸附数据符合Langmuir方程，相关系数在0．99以上，酚醛型吸附树脂吸附吡啶和N，N-二甲基苯胺属单分子层吸附：用80％的乙醇溶液作洗脱剂来洗脱吸附吡啶已达饱和的JDW-2树脂，效果是很理想的．在3．6个床体积内洗脱率达91．52％，4．8个床体积内洗脱率达到94．85％。表明酚醛型吸附树脂具有优良的洗脱性能．     

铁基超细粒子催化剂结构与还原行为的Mssbauer谱研究

铁基超细粒子催化剂具有优良的F-T反应性能。本工作利用原位Mssbauer谱辅以XRD技术研究了含有钾助剂的F-T合成铁基超细粒子催化剂的结构与还原行为,考察了催化剂组成和第二金属组分(Mn,Zn,Mg)的影响。“纯”铁超细粒子催化剂在氢气中很容易经Fe_3O_4还原为零价铁。第二金属组分的引入,一方面阻碍了催化剂的还原,另一方面稳定了Fe~(2+)的存在而使其成为还原的主要中间相,这有利于反应条件下形成类尖晶石结构的活性相。对于Fe-Mn催化剂,上述效应随锰含量的增加而更趋显著。铁基超细粒子催化剂在氢气中的还原能力依“纯”Fe>Fe-Zn>Fe-Mn>Fe-Mg的顺序递减,这在一定程度上反映了铁与第二金属组分之间相互作用的强弱。     

Monitoring the Hydrolysis of p—Nitrophenyl Acetate Catalyzed by Seryl—histidine with Electrospray Ionization Mass Spectrometry

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎｔｈｅｐａｓｔｄｅｃａｄｅ ,ｉｔｗａｓｆｏｕｎｄｔｈａｔｔｗｏａｍｉｎｏａｃｉｄｒｅｓｉｄｕｅｓ ,ＳｅｒａｎｄＨｉｓ ,ｗｏｒｋａｓｔｈｅａｃｔｉｖｅｓｉｔｅｓｉｎｔｈｅｓｅｒ ｉｎｅｐｒｏｔｅａｓｅ .1 3 Ｉｎｏｕｒｐｒｅｖｉｏｕｓｗｏｒｋ ,ａｄｉｐｅｐｔｉｄｅｓｅｒｙｌ ｈｉｓｔｉｄｉｎｅ (Ｓｅｒ Ｈｉｓ)ｗａｓｆｏｕｎｄｔｏｈａｖｅｔｈｅｐｒｏｔｅｉｎａｎｄｎｕ ｃｌｅｏｓｉｄｅｓｃｌｅａｖａｇｅａｃｔｉｖｉｔｙ .4 7ｐ Ｎｉｔｒｏｐｈｅｎｙｌａｃｅｔａｔｅ (ｐ ＮＰＡ)ｗ…     

沸石中阳离子对氮/氧吸附性能影响的研究进展

基于制氧吸附剂在变压吸附空分制氧工业应用的重要性，从沸石分子筛的氮／氧吸附性能方面，介绍了低硅沸石LSX、钙沸石、锂沸石、锂银沸石等的研究进展。讨论了沸石分子筛骨架结构和其中阳离子的种类、位置、数量与其吸附特性的关系，探讨其在变压吸附空分制氧中的应用前景。     

碳铂类似物的合成,表征及对大鼠W—256肉瘤的抑制作用

合成了十八种〔PtA_2X〕·yH_2O,其中A分别为NH_3、CH_3NH_2、1/2乙二胺和1/2(2,3-二甲基-2,3-丁二胺),X分别为1,1-环丙烷二羧酸根(CPrDCA)、2-甲-1,1-环丙烷二羧酸根(2-M-CPrDCA)、2-甲-1,1-环丁烷二羧酸根(2-M-CBDCA)、1,2-环戊烷二羧酸根(CPDCA)和1,1-环已烷二羧酸根(CHDCA),并进行了表征。测定了配合物抑制大鼠W-256肉瘤的活性,发现配合物〔Pt(NH_3)_2X〕系列按X不同有以下的活性次序:CPrDCA>2-M-CPrDCA>CPDCA>CBDCA(碳铂)≥2-M-CBDCA。     

Comparison of(η~6-Fluoroarene)tricarbonylchromium Complexes with Their Chloro-analogs in Radical Aromatic Substitutions

Reactions of fluoroarene-Cr(CO)_3 complexes with SmI_2 andcarbonyl compounds in THF/HMPA at-40— -60℃ affordedthe corresponding radical aromatic substitution products in highyield. Compared to the corresponding chloroarene-Cr.(CO)_3complexes, fluoroarene-Cr(CO)_3 complexes showed a higher ef-ficiency and slightly lower regioselectivity.     

Influences of the Hydrophobicity of the Heme-binding Pocket on the Properties and Functions of Cytochrome b_5 Mutants

IntroductionElectrontransferreactionsarethekeystepsinphoto synthesis ,respirationandmanyotherbiochemicalprocess es.1Cytochromeb5isaredoxproteinexistingwidelyinnature ,whichactsasanelectron carrierduringvariouselectrontransferprocessesinthebiologicalsystem .2Cytochromeb5isamembraneproteinwithmolecularweightofapproximately 16kDa ,ofwhichthehydrophobicC terminaldomainanchorscytochromeb5tothemem brane ,andthehydrophilicN terminaldomaincontainshemeprostheticgroupandexhibitsthebiologicalfunctionsof…