Separation of different valency states of iron,arsenic, antimony,mercury, tin and chromium by thin-layer chromatography

Summary Different valency states of iron, mercury, tin, arsenic, antimony and chromium were separated by the thin-layer chromatography on starch and cellulose, using nine different solvent systems.     

Synthesis and antimicrobial activity of new functionalized derivatives of [1,2,4]triazolo[4,3‐a]pyrimidin‐5(1H)‐one

New functionalized 1,7‐diaryl‐6‐cyano‐1,2,4‐triazolo[4,3‐a]pyrimidin‐5(1H)‐one derivatives ( 5a–j ) were synthesized via reaction of 5‐cyano‐6‐phenyl‐2‐thiouracil 1 with the respective hydrazonoyl halides 2a–j and their biological activity was evaluated. The mechanism and the regioselectivity of the studied reactions are discussed. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:393–398, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20311     

2,8‐Di­hydroxy‐1,3,7,9‐tetra­methyl‐6,12‐di­hydro­dipyrido­[1,2‐a:1′,2′‐d]pyrazine­diyl­ium dichloride dihydrate

The 2,8‐di­hydroxy‐1,3,7,9‐tetra­methyl‐6,12‐di­hydro­di­pyrido[1,2‐a:1′,2′‐d]pyrazine­diyl­ium dication possesses 2/m symmetry and lies in the mirror plane together with a chloride anion and the water O atom. The dication also lies on an inversion centre, i.e. C₁₆H₂₀N₂O₂²⁺·2Cl^?·2H₂O. Due to these symmetry constrictions the dication adopts an unexpected planar conformation. Molecules are linked by O—H?O and O—H?Cl hydrogen bonds to form chains, which are cross‐connected by C—H?Cl attractive interactions forming a complex three‐dimensional hydrogen‐bond network.     

Addition of Isocyanides to Tetramesityldigermene: A Comparison of the Reactivity between Surface and Molecular Digermenes

The reaction of benzyl isocyanide, tert‐butyl isocyanide, and 2,6‐dimethylphenyl isocyanide with tetramesityldigermene (Mes₂Ge=GeMes₂) was examined. Whereas the addition of benzyl isocyanide gave the C?NC activation product, Mes₂Ge(CH₂Ph)Ge(CN)Mes₂, tert‐butyl isocyanide, and 2,6‐dimethylphenyl isocyanide did not give stable adducts, rather the rate of conversion of the digermene to the corresponding cyclotrigermane was accelerated. A comparison between the reactivity of the isocyanides with Mes₂Ge=GeMes₂ and the Ge(100)‐2×1 surface was made and some insights into the surface chemistry are offered.     

Heat transfer and fluid flow around semi-circular tube in cross flow at different orientations

Fluid flow and heat transfer characteristics around a semi-circular tube in cross flow were experimentally and numerically investigated. Three different tube-flow arrangements were considered. Firstly, the flat surface of the tube was placed parallel to the freestream flow; secondly, the flat surface of the tube was facing the upstream flow and thirdly, the curved surface of the tube was facing the upstream flow. For the second and the third arrangements, different angles of attack were studied. Flow visualization was carried out to illustrate streamlines around the tube and to verify flow patterns obtained from the numerical calculations. It was found that: (1) for any angle of attack, the arrangement of the curved surface facing the flow gave higher average Nusselt number than the arrangement of the flat surface facing the flow and (2) for all tube-flow arrangements, increasing the angle of attack slightly increases the average Nusselt number. Correlations of Nusselt numbers in terms of Reynolds number and angle of attack were deduced from the experimental results for the three arrangements. The comparisons between the experimental data, correlations’ predictions and numerical results showed reasonable agreements.     

Slot/slots air jet impinging cooling of a cylinder for different jets–cylinder configurations

Heat transfer characteristics of a slot/slots jet air impinging on a cylinder have been experimentally investigated for two different orientations of slot/slots jet plan with respect to cylinder axis. The experiments were carried out to study the effects of orientation of slot/slots jet plan with respect to cylinder axis on the rate of heat transfer from the cylinder. Two different jet–cylinder configurations were studied: (1) single slot jet aligned with cylinder axis (slot length = cylinder length), and (2) multiple slot jets equally spaces distributed orthogonal to cylinder axis (each slot length = cylinder diameter and sum of slots lengths = cylinder length). For each configuration, parametric effects of Reynolds numbers (Re) ranging from 1,000 to 10,000, dimensionless slot widths (W/d) ranging from 0.125 to 0.5, and dimensionless slot orifice-to-cylinder spacing (Z/W) ranging from 1 to 12 on local and average Nusselt numbers around cylinder surface have been investigated. The results showed that: (1) cooling the cylinder by multiple slots jets situated orthogonal to cylinder axis gave more uniform surface temperature distributions and higher heat transfer rate than the case of cooling the cylinder by single slot jet aligned with cylinder axis, (2) for both configurations the Nusselt number around the cylinder increased with increasing Re and W/d, and (3) for both configurations there was a certain Z/W in the range 4<Z/W<6 at which the stagnation and mean Nusselt number were maximum. Correlations for the mean Nusselt numbers around cylinder surface have been presented for both configurations. Comparisons between the correlations predictions and the present and other previous experimental data have been conducted.     

Determination of morphine at gold nanoparticles/Nafion® carbon paste modified sensor electrode

A novel and effective electrochemical sensor for the determination of morphine (MO) in 0.04 mol L(-1) universal buffer solution (pH 7.4) is introduced using gold nanoparticles electrodeposited on a Nafion modified carbon paste electrode. The effect of various experimental parameters including pH, scan rate and accumulation time on the voltammetric response of MO was investigated. At the optimum conditions, the concentration of MO was determined using differential pulse voltammetry (DPV) in a linear range of 2.0 × 10(-7) to 2.6 × 10(-4) mol L(-1) with a correlation coefficient of 0.999, and a detection limit of 13.3 × 10(-10) mol L(-1), respectively. The effect of common interferences on the current response of morphine namely ascorbic acid (AA) and uric acid (UA) is studied. The modified electrode can be used for the determination of MO spiked into urine samples, and excellent recovery results were obtained.     

TLC—Densitometric Determination of Guaifenesin,Pseudoephedrine Hydrochloride and Guaifenesin Related Substance (Guaiacol)

JPC – Journal of Planar Chromatography – Modern TLC - This research article describes a simple and sensitive thin-layer chromatographic (TLC)-densitometric method for simultaneous...