Regioselective strategies mediated by lanthanide triflates for efficient assembly of oligomannans

Readily prepared mannosyl n-pentenylorthoesters (NPOEs) serve as donors in themselves and as convenient intermediates for other glycosyl donors, such as n-pentenyl glycosides (NPGs), thioglycosides, and trichloroacetimidates. These various donors are activated by different reagents, and are therefore amenable to versatile, discriminate use. Scandium and ytterbium triflates respond very differently to these donors, with the result that chemoselective discrimination between NPOEs, NPGs, trichloroacetimidates as well as ethyl and phenyl thioglycosides can be achieved. Appropriate NPOEs are also able to provide 2,6 and 3,6 diol acceptors via rearrangement or glycoside formation, and these can be used for one-pot, sequential glycosidations based on orthogonal donors, and in situ double differential glycosidations. Thus NPOEs activated by iodonium ion, specifically generated from ytterbium triflate/N-iodosuccinimide, can be used to monoglycosidate the diols rapidly, with exquisite regio, and sometimes chemo, selectivity. The residual NPOE is converted into disarmed NPG, which is refractory to the reaction conditions, and so poses no threat to the free-OH of the monoglycosidation product. Further glycosidation of the latter can then achieved by direct addition of a trichloroacetimidate or ethyl thioglycoside. This basic strategy has been used to prepare a branched chain pentadecamannan. The success is an example of the efficiency of donor/acceptor MATCH concept for regioselective glycosylation.     

Micellar effect of sodium dodecyl sulfate on the reactions between iron(II) and p-benzoquinone, and iron(III) and hydroquinone

The micellar effet of sodium dodecyl sulfate (SDS) on the initial stages of the reaction between (1) Fe(II) and p-benzoquinone, and (2) Fe(III) and hydroquinone have been investigated. In the former case acceleration was observed, the rate-[surfactant] profile showing a maximum. SDS has an inhibitory effect on the latter reaction. Kinetic analysis has been carried out using Berezin's approach.

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() 1) Fe(II) 2) Fe(III) . - . . , .

     

Determination of Y,Sm, Eu,Gd, Dy,Ho, Er in high purity terbium oxide by ICP-AES

Inductively coupled plasma atomic emission spectrometry (ICP-AES) was employed to determine Y, Sm, Eu, Gd, Dy, Ho and Er in high purity terbium oxide. Terbium oxide was dissolved in 0.5 mol/l HNO₃ and nebulized into the plasma generated by a 56 MHz RF generator at 1.5 kW output power. Using a Jobin-Yvon 1-m Czenry-Turner high resolution, high dispersion scanning monochromator, lines mutually interference-free as well as free of interference from the matrix Tb were chosen for the seven analytes. A set of standards containing the analytes in the concentration range 0.01–1.0 gmg/ml with 1 mg/ml Tb was used for calibration. It was necessary to apply background correction to the gross analyte line intensities in order to obtain linear calibration plots for the analytes.     

Design,synthesis, and biological activity studies of a new class of sulfonated aurones: First synthesis of acidoaurone isolated from Phyllanthus acidus

A novel series of aurones were designed by introducing sulfonic acid group on ring-A and ring-B of known natural aurones such as hispidol, sulfuretin, maritimetin, and aureusidin. These sulfonated aurones were synthesized by a unique approach. Sulfonation on ring-A or ring-B converts water-insoluble aurones into highly water-soluble aurones. The sulfonated aurones were tested for their antioxidant, antiinflammatory, and AChE inhibition activities along with their natural aurones. Ring-A sulfonated aurones displayed higher antioxidant activity, 5-LOX, and AChE inhibition in comparison with their corresponding natural aurones. Ring-B sulfonated aurones exhibited potent 5-LOX inhibitory activity and significant antioxidant activity. Acidoaurone, a first sulfonated aurone isolated from Phyllanthus acidus was synthesized for the first time and was well characterized using NMR, LC–MS, and further confirmed by HMBC.     

A problem in enumerating extreme points, and an efficient algorithm for one class of polytopes

We consider the problem of developing an efficient algorithm for enumerating the extreme points of a convex polytope specified by linear constraints. Murty and Chung (Math Program 70:27–45, 1995) introduced the concept of a segment of a polytope, and used it to develop some steps for carrying out the enumeration efficiently until the convex hull of the set of known extreme points becomes a segment. That effort stops with a segment, other steps outlined in Murty and Chung (Math Program 70:27–45, 1995) for carrying out the enumeration after reaching a segment, or for checking whether the segment is equal to the original polytope, do not constitute an efficient algorithm. Here we describe the central problem in carrying out the enumeration efficiently after reaching a segment. We then discuss two procedures for enumerating extreme points, the mukkadvayam checking procedure, and the nearest point procedure. We divide polytopes into two classes: Class 1 polytopes have at least one extreme point satisfying the property that there is a hyperplane H through that extreme point such that every facet of the polytope incident at that extreme point has relative interior point intersections with both sides of H; Class 2 polytopes have the property that every hyperplane through any extreme point has at least one facet incident at that extreme point completely contained on one of its sides. We then prove that the procedures developed solve the problem efficiently when the polytope belongs to Class 2.     

Reductions of points on elliptic curves

Let E be an elliptic curve defined over \mathbbQ{\mathbb{Q}}. Let Γ be a subgroup of rank r of the group of rational points E(\mathbbQ){E(\mathbb{Q})} of E. For any prime p of good reduction, let [`(G)]{\bar{\Gamma}} be the reduction of Γ modulo p. Under certain standard assumptions, we prove that for almost all primes p (i.e. for a set of primes of density one), we have

Studies on the extraction of vanadium (IV) in the presence of some anions and neutral oxygen donors

Extraction of vanadium (IV) in the presence of perchlorate, nitrate, halides, and thiocyanate and neutral oxygen donors liken-butanol, TBP and antipyrine into various solvents is studied. Composition of the extracting species and the stability constants are determined. The effectiveness of the three neutral oxygen donors studied in the extraction of vanadium (IV)-anion systems is found to follow the order: antipyrine > TBP >n-butanol.     

Aberration-corrected catadioptric magnifiers useful for simple microfiche readers

The present paper considers the magnifying power and aberration properties of three different catadioptric magnifying systems useful for application as simple hand-held microfiche readers. These are in the form of a plano-convex lens, a meniscus lens and an achromatic doublet lens and all their outer surfaces have been coated with a semi-reflecting film so that they behave like catadioptric elements. These can be designed to give magnification in the range of 15 × to 25 × with sufficient eye relief. Using such magnifiers, it is possible to read microfiche having frame sizes of 16 × 12 mm and 12 × 9 mm. The cemented achromatic doublet coated on the outer surfaces seems to give a very good image for use in microfiche reader.     

Determination of trace elements in rocks by optical emission spectroscopy: A new method of internal standardization

Summary A method has been described for the determination of twelve trace elements (Pb, Sn, Cr, Co, Ni, V, Y, La, Zr, Cu, Zn, Sc) in different types of rocks using optical emission Spectroscopy (OES). The method employs a single set of synthetic standards for analysing any type of rock, basic, acidic or intermediate. When an external element, such as osmium, has been added to serve as internal standard, the analytical data showed poor precision. A new method of internal standardization has, therefore, been attempted. In this, a line due to silicon whose intensity is influenced by two adjacent Fe lines, has been used as the internal standard. Such an approach gave better presision (expressed in terms of coefficient of variation). Six international rock standards have been analysed and the data obtained have been compared with that previously reported.

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Bestimmung von Spurenelementen in Gesteinen durch optische Emissions-Spektroskopie: Ein neues Verfahren zur inneren Eichung

Zusammenfassung Zwölf Spurenelemente (Pb, Sn, Cr, Co, Ni, V, Y, La, Zr, Cu, Zn, Sc) werden in verschiedenen Gesteinstypen bestimmt. Basische, saure und intermediäre Gesteine können mit einem einzigen Satz synthetischen Standards analysiert werden. Bei Benutzung eines externen Elements (Os) zur Eichung wurden schlechte Ergebnisse erhalten. Bei dem neuen Verfahren wird eine bessere Reproduzierbarkeit (ausgedrückt als Variationskoeffizient) durch Verwendung einer Siliciumlinie, die durch benachbarte Eisenlinien beeinflußt wird, erzielt. Sechs internationale Standardgesteinsproben wurden nach diesem Verfahren untersucht und die Ergebnisse mit früher erhaltenen verglichen.