全文获取类型
收费全文 | 447篇 |
免费 | 15篇 |
国内免费 | 4篇 |
专业分类
化学 | 266篇 |
晶体学 | 11篇 |
力学 | 20篇 |
数学 | 51篇 |
物理学 | 118篇 |
出版年
2023年 | 5篇 |
2022年 | 7篇 |
2021年 | 11篇 |
2020年 | 13篇 |
2019年 | 13篇 |
2018年 | 6篇 |
2017年 | 5篇 |
2016年 | 14篇 |
2015年 | 15篇 |
2014年 | 11篇 |
2013年 | 23篇 |
2012年 | 21篇 |
2011年 | 37篇 |
2010年 | 13篇 |
2009年 | 22篇 |
2008年 | 32篇 |
2007年 | 28篇 |
2006年 | 20篇 |
2005年 | 26篇 |
2004年 | 11篇 |
2003年 | 15篇 |
2002年 | 10篇 |
2001年 | 10篇 |
2000年 | 15篇 |
1999年 | 5篇 |
1998年 | 3篇 |
1997年 | 2篇 |
1996年 | 6篇 |
1995年 | 6篇 |
1994年 | 1篇 |
1993年 | 3篇 |
1992年 | 10篇 |
1991年 | 4篇 |
1990年 | 5篇 |
1989年 | 4篇 |
1988年 | 1篇 |
1987年 | 3篇 |
1986年 | 2篇 |
1985年 | 5篇 |
1984年 | 8篇 |
1983年 | 2篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1974年 | 1篇 |
1962年 | 1篇 |
排序方式: 共有466条查询结果,搜索用时 0 毫秒
31.
Nasibulin Albert G. Kauppinen Esko I. Thomson Bruce A. Fernandez de la Mora J. 《Journal of nanoparticle research》2002,4(5):449-453
Polyethylene glycol (PEG) molecules with masses below 1300amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles. 相似文献
32.
Martínez-Teipel B Teixidó J Pascual R Mora M Pujolà J Fujimoto T Borrell JI Michelotti EL 《Journal of combinatorial chemistry》2005,7(3):436-448
Heterocyclic demonstration libraries for agrochemical screening were prepared from the common intermediates 2-methoxy-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitriles (1), using standard solution-phase techniques. A total of 18 screening libraries were prepared in good to excellent yields. Several members of these libraries were active in the first level of agrochemical screening, especially in the fungicide screen. 相似文献
33.
Giuseppe Pennisi Cyrille Stephan Etienne Gourc Guilhem Michon 《Nonlinear dynamics》2017,88(3):1769-1784
In this paper, the dynamics of a system composed of a harmonically forced single-degree-of-freedom linear oscillator coupled to a vibro-impact nonlinear energy sink (VI-NES) is experimentally investigated. The mass ratio between the VI-NES and the primary system is about \(1\%\). Depending on the external force’s amplitude and frequency, either a strongly modulated response (SMR) or a constant amplitude response (CAR) is observed. In both cases, an irreversible transfer of energy occurs from the linear oscillator toward the VI-NES: process known in the literature as passive targeted energy transfer. Furthermore, the problem is analytically studied by using the method of multiple scales. The obtained slow invariant manifold shows the existence of a stable and of an unstable branch of solutions, as well as of an energy threshold (a saddle-node bifurcation) for the solutions to appear. Subsequently, the fixed points of the problem are calculated. When a stable fixed point is reached, the system is naturally drawn to it and a CAR is established, whereas when no stable point is attained, the system exhibits a SMR regime. Finally, a good correlation between the experimental and the analytical results is presented. 相似文献
34.
The crystal structure of the new quaternary compound CuTa2InTe4 was studied using X-ray powder diffraction data. The powder pattern refined by the Rietveld method indicates that this material crystallizes in the tetragonal system with space group I-4¯2m (No. 121), Z=2, and unit cell parameters a=6.1963(2) Å, c=12.4164(4) Å, c/a=2.00 and V=476.72(3) Å3. The structural and instrumental refinement of 28 parameters led to Rp=10.4%, Rwp=11.1%, Rexp=6.8% and χ2=2.7 for 96 independent reflections. 相似文献
35.
Ana R. Millanao Aracely Y. Mora Nicols A. Villagra Sergio A. Bucarey Alejandro A. Hidalgo 《Molecules (Basel, Switzerland)》2021,26(23)
Broad antibacterial spectrum, high oral bioavailability and excellent tissue penetration combined with safety and few, yet rare, unwanted effects, have made the quinolones class of antimicrobials one of the most used in inpatients and outpatients. Initially discovered during the search for improved chloroquine-derivative molecules with increased anti-malarial activity, today the quinolones, intended as antimicrobials, comprehend four generations that progressively have been extending antimicrobial spectrum and clinical use. The quinolone class of antimicrobials exerts its antimicrobial actions through inhibiting DNA gyrase and Topoisomerase IV that in turn inhibits synthesis of DNA and RNA. Good distribution through different tissues and organs to treat Gram-positive and Gram-negative bacteria have made quinolones a good choice to treat disease in both humans and animals. The extensive use of quinolones, in both human health and in the veterinary field, has induced a rise of resistance and menace with leaving the quinolones family ineffective to treat infections. This review revises the evolution of quinolones structures, biological activity, and the clinical importance of this evolving family. Next, updated information regarding the mechanism of antimicrobial activity is revised. The veterinary use of quinolones in animal productions is also considered for its environmental role in spreading resistance. Finally, considerations for the use of quinolones in human and veterinary medicine are discussed. 相似文献
36.
37.
Prof. María Laura Uhrig Erwin W. Mora Flores Prof. Al Postigo 《Chemistry (Weinheim an der Bergstrasse, Germany)》2021,27(29):7813-7825
Fluoroalkyl-substituted carbohydrates play relevant roles in diverse areas such as supramolecular chemistry, glycoconjugation, liquid crystals, and surfactants, with direct applications as wetting, antifreeze, and coating agents. In light of these promising applications, new methodologies for the late-stage incorporation of fluoroalkyl RF groups into carbohydrates and derivatives are herein presented as they are relevant to the synthetic carbohydrate community. Previously reviewed protocols for the installation of RF groups onto carbohydrates and derivatives will be succinctly summarized in the light of the new achievements. Fluoroalkyl-substituted iminosugars, on the other hand, are also interesting glycomimetic derivatives with prominent roles as glycosidases and glycosyltransferases inhibitors, as has recently been demonstrated. Also, they positively contribute to the study of sugar–protein interactions and enzyme mechanisms. New advances in the syntheses of fluoroalkyl-substituted iminosugars will also be presented here. 相似文献
38.
D. Shooter S. J. de Mora A. Grout D. J. Wylie He Zhi-yun 《International journal of environmental analytical chemistry》2013,93(4):239-249
Abstract A technique was developed using sparging and pre-concentration onto a Tenax trap at ambient temperature allowing field measurements to be made of reduced sulfur gases in Antarctic marine and glacial melt waters. Following thermal desorption, gases were determined by gas chromatography using a flame photometric detector. Detection limits in ng 1?1 were: H2S 50, OCS 8, SO2 160, CH3SH 6, CH3SCH3 20 and CS2 2. Storage of melt water samples for more than 24 hours resulted in concentration changes of the reduced sulfur gases present. While the Antarctic environment imposed limitations on the analytical method, an investigation of various pond and marine waters was undertaken. 相似文献
39.
Richard St‐Louis Stephen de Mora milien Pelletier Bill Doidge Daniel Leclair Igor Mikaelian Daniel Martineau 《应用有机金属化学》2000,14(4):218-226
Butyltin (tributyltin TBT; dibutyltin DBT and monobutyltin MBT) speciation was measured in the liver of beluga whales from the St Lawrence Estuary and Hudson Strait (northern Quebec). Using GC–MS, liver samples were analysed from 21 beluga whales found dead, stranded along the shores of the St Lawrence during the period 1995–1998. In all cases, including a neonate specimen, the liver was contaminated with butyltin compounds with concentrations in the range 0.04–2.1 mg Sn kg−1 on a dry weight basis. Liver samples of five beluga whales from Hudson Strait obtained in the summer of 1998 were also analysed. For these animals, hepatic butyltin concentrations were consistently below the detection limit (<0.5 ng Sn g−1 for MBT and <0.2 ng Sn g−1 for DBT and TBT). Compared with published data on the contamination by TBT of the marine mammals of the St Lawrence in 1988, these contemporary results clearly indicate that the level of contamination of the beluga whales in this coastal marine ecosystem has not decreased ten years after regulating the use of TBT‐based antifoulants on small craft. Copyright © 2000 John Wiley & Sons, Ltd. 相似文献
40.
Stashenko EE Mora AL Cervantes ME Martínez JR 《Journal of chromatographic science》2006,44(6):347-353
Specific chromatographic methodologies are developed for the analysis of carboxylic acids (C(2)-C(6), benzoic) and aldehydes (C(2)-C(10)) of low molecular weight in diverse matrices, such as air, automotive exhaust gases, human breath, and aqueous matrices. For carboxylic acids, the method is based on their reaction with pentafluorobenzyl bromide in aqueous solution, followed by the separation and identification of the resultant pentafluorobenzyl esters by means of headspace (HS)-solid-phase microextraction (SPME) combined with gas chromatography (GC) and electron capture detection (ECD). Detection limits in the microg/m(3) range are reached, with relative standard deviation (RSD) less than 10% and linear response (R(2) > 0.99) over two orders of magnitude. The analytical methodology for aldehydes is based on SPME with simultaneous derivatization of the analytes on the fiber, by reaction with pentafluorophenylhydrazine. The derivatization reagent is previously deposited on the SPME fiber, which is then exposed to the gaseous matrix or the HS of the sample solution. The pentafluorophenyl hydrazones formed on the fiber are analyzed selectively by means of GC-ECD, with detection limits in the ng/m(3) range, RSD less than 10%, and linear response (R(2) > 0.99) over two orders of magnitude. 相似文献