全文获取类型
收费全文 | 343篇 |
免费 | 3篇 |
国内免费 | 5篇 |
专业分类
化学 | 182篇 |
晶体学 | 5篇 |
力学 | 4篇 |
数学 | 79篇 |
物理学 | 81篇 |
出版年
2024年 | 1篇 |
2023年 | 5篇 |
2022年 | 2篇 |
2021年 | 12篇 |
2020年 | 12篇 |
2019年 | 6篇 |
2018年 | 5篇 |
2017年 | 7篇 |
2016年 | 6篇 |
2015年 | 10篇 |
2014年 | 9篇 |
2013年 | 28篇 |
2012年 | 16篇 |
2011年 | 32篇 |
2010年 | 13篇 |
2009年 | 11篇 |
2008年 | 18篇 |
2007年 | 26篇 |
2006年 | 12篇 |
2005年 | 12篇 |
2004年 | 15篇 |
2003年 | 21篇 |
2002年 | 16篇 |
2001年 | 9篇 |
2000年 | 12篇 |
1999年 | 3篇 |
1998年 | 4篇 |
1997年 | 6篇 |
1996年 | 2篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1992年 | 2篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1988年 | 2篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1977年 | 2篇 |
排序方式: 共有351条查询结果,搜索用时 15 毫秒
341.
The energy barrier of a magnetic domain wall trapped at a defect is measured experimentally. When the domain wall is pushed by an electric current and/or a magnetic field, the depinning time from the barrier exhibits perfect exponential distribution, indicating that a single energy barrier governs the depinning. The electric current is found to generate linear and quadratic contributions to the energy barrier, which are attributed to the nonadiabatic and adiabatic spin-transfer torques, respectively. The adiabatic spin-transfer torque reduces the energy barrier and, consequently, causes depinning at lower current densities, promising a way toward low-power current-controlled magnetic applications. 相似文献
342.
Boo Rim Choe 《Journal of Mathematical Analysis and Applications》2011,379(2):889-909
Recently Li et al. have characterized, except for a critical case, the weighted Bergman spaces over the complex ball by means of integrability conditions of double integrals associated with difference quotients of holomorphic functions. In this paper we extend those characterizations to the case of weighted harmonic Bergman spaces over the real ball and complement their results by providing a characterization for the missing critical case. We also investigate the possibility of extensions to the half-space setting. Our observations reveal an interesting half-space phenomenon caused by the unboundedness of the half-space. 相似文献
343.
Boo Rim Choe 《Journal of Mathematical Analysis and Applications》2011,381(1):365-382
On the Hardy space over the unit ball in Cn, we consider operators which have the form of a finite sum of products of several Toeplitz operators. We study characterizing problems of when such an operator is compact or of finite rank. Some of our results show higher-dimensional phenomena. 相似文献
344.
We introduce a new importance sampling method for pricing basket default swaps employing exchangeable Archimedean copulas and nested Gumbel copulas. We establish more realistic dependence structures than existing copula models for credit risks in the underlying portfolio, and propose an appropriate density for importance sampling by analyzing multivariate Archimedean copulas. To justify efficiency and accuracy of the proposed algorithms, we present numerical examples and compare them with the crude Monte Carlo simulation, and finally show that our proposed estimators produce considerably smaller variances. 相似文献
345.
The potential energy surface (PES) for the formation of C(4)H(4)(?+) from the pyridine radical cation by loss of HCN was determined from quantum chemical calculations using the G3//B3LYP method. The complete reaction pathways for the formation of the low-energy C(4)H(4)(?+) isomers, radical cations of methylenecyclopropene (MCP(?+)), vinylacteylene (VA(?+)), cyclobutadiene, and butatriene were obtained. Based on the PESs, a Rice-Ramsperger-Kassel-Marcus model calculation was performed to investigate the dissociation kinetics. The calculated dissociation rate constants agreed with the previous experimental data. It was predicted that a mixture of MCP(?+) and VA(?+) was formed by loss of HCN. The formation of MCP(?+) was more favored near the dissociation threshold and at high energies, whereas the formation of VA(?+) was more favored at the low energies corresponding to the ion lifetime of microseconds. 相似文献
346.
Seo JB Choe SS Jeong HW Park SW Shin HJ Choi SM Park JY Choi EW Kim JB Seen DS Jeong JY Lee TG 《Experimental & molecular medicine》2011,43(4):205-215
Lysimachia foenum-graecum has been used as an oriental medicine with anti-inflammatory effect. The anti-obesity effect of L. foenum-graecum extract (LFE) was first discovered in our screening of natural product extract library against adipogenesis. To characterize its anti-obesity effects and to evaluate its potential as an anti-obesity drug, we performed various obesity-related experiments in vitro and in vivo. In adipogenesis assay, LFE blocked the differentiation of 3T3-L1 preadipocyte in a dose-dependent manner with an IC50 of 2.5 μg/ml. In addition, LFE suppressed the expression of lipogenic genes, while increasing the expression of lipolytic genes in vitro at 10 μg/ml and in vivo at 100 mg/kg/day. The anti-adipogenic and anti-lipogenic effect of LFE seems to be mediated by the inhibition of PPARγ and C/EBPα expression as shown in in vitro and in vivo, and the suppression of PPARγ activity in vitro. Moreover, LFE stimulated fatty acid oxidation in an AMPK-dependent manner. In high-fat diet (HFD)-induced obese mice (n = 8/group), oral administration of LFE at 30, 100, and 300 mg/kg/day decreased total body weight gain significantly in all doses tested. No difference in food intake was observed between vehicle- and LFE-treated HFD mice. The weight of white adipose tissues including abdominal subcutaneous, epididymal, and perirenal adipose tissue was reduced markedly in LFE-treated HFD mice in a dose-dependent manner. Treatment of LFE also greatly improved serum levels of obesity-related biomarkers such as glucose, triglycerides, and adipocytokines leptin, adiponectin, and resistin. All together, these results showed anti-obesity effects of LFE on adipogenesis and lipid metabolism in vitro and in vivo and raised a possibility of developing LFE as anti-obesity therapeutics. 相似文献
347.
348.
Chia-Yen Wu Dosh Whye Lisa Glazewski Leila Choe Douglas Kerr Kelvin H Lee Robert W Mason Wenlan Wang 《BMC neuroscience》2011,12(1):25
Background
Deletion or mutation(s) of the survival motor neuron 1 (SMN1) gene causes spinal muscular atrophy (SMA), a neuromuscular disease characterized by spinal motor neuron death and muscle paralysis. Complete loss of the SMN protein is embryonically lethal, yet reduced levels of this protein result in selective death of motor neurons. Why motor neurons are specifically targeted by SMN deficiency remains to be determined. In this study, embryonic stem (ES) cells derived from a severe SMA mouse model were differentiated into motor neurons in vitro by addition of retinoic acid and sonic hedgehog agonist. Proteomic and western blot analyses were used to probe protein expression alterations in this cell-culture model of SMA that could be relevant to the disease. 相似文献349.
Sang-Young Kim Chi-Bong Choi Hyun-Sung Lee Sung-Ho Lee Dong-Cheol Woo Hwi-Yool Kim Kwan-Soo Hong Chul-Hyun Lee Bo-Young Choe 《Magnetic resonance imaging》2010
The forced swimming test (FST) is a useful paradigm that is relatively quick and simple to perform and has been utilized to predict antidepressant activity based on learned helplessness as a model of depression. To date, few studies have used proton magnetic resonance spectroscopy (1H-MRS) to assess antidepressant effects in rats. The purpose of this study was to assess desipramine (DMI) effects on the left dorsolateral prefrontal cortex (DLPFC) of the rats, which were randomly assigned to three groups (control, n=10; FST+saline, n=10; FST+DMI, n=10), using single-voxel localization technique. All 1H-MRS experiments were performed on a Bruker 4.7-T scanner with 400 mm bore magnet, allowing for acquisition of in vivo 1H point-resolved spectroscopy spectra (TR/TE=3000/30 ms, number of data points=2048, NEX=512, voxel volume=27 μl, scan time=25 min). Proton metabolites were quantified automatically using LCModel software and were expressed as ratios to total creatine (Cr+PCr). Major target metabolites such as N-acetyl aspartate (NAA)+N-acetylaspartylglutamate (NAAG), glutamate+glutamine (Glu+Gln), glycerophosphorylcholine+phosphorylcholine (GPC+PCho), myo-inositol (mIns) and taurine (Tau) were successfully quantified with Cramer–Rao lower boundary ≤10%. There were significantly higher mIns/(Cr+PCr) and mIns/(NAA+NAAG) ratios in the FST+saline group compared to the control group. In the FST+DMI group, both mIns/(Cr+PCr) and mIns/(NAA+NAAG) ratios were significantly decreased to the level similar to those in the control group. No other metabolite ratios were significantly different among the three groups. Our findings suggest a possible role of altered mIns level within the left DLPFC of the rat model for depression. 相似文献
350.
Dr. Katsuhiko Takeuchi Ming-Yu Chen Dr. Hao-Yu Yuan Dr. Hiroki Koizumi Dr. Kazuhiro Matsumoto Dr. Norihisa Fukaya Dr. Yoong-Kee Choe Shinji Shigeyasu Seiji Matsumoto Dr. Satoshi Hamura Prof. Dr. Jun-Chul Choi 《Chemistry (Weinheim an der Bergstrasse, Germany)》2021,27(72):18066-18073
We have successfully isolated and characterized the zinc carbamate complex (phen)Zn(OAc)(OC(=O)NHPh) ( 1 ; phen=1,10-phenanthroline), formed as an intermediate during the Zn(OAc)2/phen-catalyzed synthesis of organic carbamates from CO2, amines, and the reusable reactant Si(OMe)4. Density functional theory calculations revealed that the direct reaction of 1 with Si(OMe)4 proceeds via a five-coordinate silicon intermediate, forming organic carbamates. Based on these results, the catalytic system was improved by using Si(OMe)4 as the reaction solvent and additives like KOMe and KF, which promote the formation of the five-coordinated silicon species. This sustainable and effective method can be used to synthesize various N-aryl and N-alkyl carbamates, including industrially important polyurethane raw materials, starting from CO2 under atmospheric pressure. 相似文献