全文获取类型
收费全文 | 848篇 |
免费 | 28篇 |
国内免费 | 1篇 |
专业分类
化学 | 631篇 |
晶体学 | 10篇 |
力学 | 11篇 |
数学 | 64篇 |
物理学 | 161篇 |
出版年
2023年 | 6篇 |
2022年 | 40篇 |
2021年 | 24篇 |
2020年 | 24篇 |
2019年 | 35篇 |
2018年 | 18篇 |
2017年 | 31篇 |
2016年 | 25篇 |
2015年 | 27篇 |
2014年 | 27篇 |
2013年 | 54篇 |
2012年 | 49篇 |
2011年 | 32篇 |
2010年 | 27篇 |
2009年 | 15篇 |
2008年 | 35篇 |
2007年 | 25篇 |
2006年 | 27篇 |
2005年 | 28篇 |
2004年 | 22篇 |
2003年 | 27篇 |
2002年 | 27篇 |
2001年 | 18篇 |
2000年 | 11篇 |
1999年 | 10篇 |
1997年 | 5篇 |
1996年 | 11篇 |
1995年 | 8篇 |
1994年 | 4篇 |
1993年 | 13篇 |
1992年 | 9篇 |
1991年 | 7篇 |
1989年 | 6篇 |
1988年 | 5篇 |
1987年 | 8篇 |
1985年 | 9篇 |
1984年 | 13篇 |
1983年 | 8篇 |
1982年 | 6篇 |
1981年 | 9篇 |
1980年 | 11篇 |
1979年 | 6篇 |
1978年 | 9篇 |
1977年 | 11篇 |
1976年 | 6篇 |
1975年 | 8篇 |
1974年 | 4篇 |
1973年 | 5篇 |
1972年 | 5篇 |
1969年 | 3篇 |
排序方式: 共有877条查询结果,搜索用时 46 毫秒
861.
Ali Ramazani Mona Ashtari Ali Souldozi Yavar Ahmadi 《Phosphorus, sulfur, and silicon and the related elements》2013,188(9):1064-1073
Abstract Reaction of N-isocyaniminotriphenylphosphorane with benzaldehyde derivatives in the presence of 3-phenyl-2-propynoic acid and secondary amines proceeds smoothly at room temperature and under neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions are observed. 相似文献
862.
Mona Kiani Hamidreza Aghabozorg Kheirollah Jafari Jozani Alimorad Rashidi Mahboobeh Mohsennia 《Phosphorus, sulfur, and silicon and the related elements》2013,188(9):1254-1261
Abstract Ni2P nanoparticles supported by functionalized carbon nanotubes (CNTs) were prepared for the first time. Nickel (II) dihydrogenphosphite as a source of nickel, with different loadings on the functionalized CNTs, were used. The prepared samples were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR) techniques. Surface areas of the samples were measured by using Brunauer, Emmett and Teller (BET) method. The catalytic activity of the prepared samples was studied in hydrodesulfurization (HDS) of naphtha. The results showed that the CNTs were functionalized and Ni2P particles were dispersed on the functionalized CNTs. It was also indicated that the pores size of Ni2P particles were less than 20 nm. The catalytic study of the prepared samples confirmed that these compounds were stable and active in the process. Removal of sulfur from the desired naphtha in presence of the samples depended on the nickel loadings and increased with temperature in all cases. 相似文献
863.
Mona Hosseini‐Sarvari 《合成通讯》2013,43(6):832-840
Efficient electrophilic substitution reactions of indoles with various aromatic aldehydes were carried out using a catalytic amount of ZnO under solvent‐free conditions to afford the corresponding bis(indolyl)methanes in excellent yields. Among the various methods published for the synthesis of bis(indolyl)methane, ZnO is a very cheap, environmentally friendly, and reusable catalyst that can be used for synthesis of a new range of bis(indolyl)methane derivatives. 相似文献
864.
A new high‐yielding, operationally simple, solvent‐free, and mild method for preparation of pyrazolines, tetrahydrocarbazoles, and indoles has been developed using KHSO4 · H2O impregnated on SiO2. The reactions have been probed under microwave irradiation (MWI), and ultrasonic and thermal conditions, employing different solid supports. The data revealed that KHSO4 · H2O impregnated on SiO2 under MWI provides the best yields in a shorter time under solvent‐free reaction conditions. 相似文献
865.
Mohamed M. Ghoneim Amera M. Hassanein Nehal A. Salahuddin Hanaa S. El-Desoky Mona N. Elfiky 《Journal of Solid State Electrochemistry》2013,17(7):1891-1902
The electrochemical behavior of vardenafil HCl (VRL) at a carbon paste electrode (CPE) was investigated by cyclic voltammetry, and the mechanism of its oxidation was suggested and discussed. A simple Nujol-based CPE in combination with a sensitive square-wave adsorption anodic stripping voltammetry method was described for trace determination of VRL. The described method showed excellent performance for trace determination of VRL in its formulation “Levitra® tablets” without interference from excipients. The results were statistically compared with those obtained with an established HPLC method; nonsignificant differences were found between the described voltammetric and HPLC methods. The described stripping voltammetric method is highly sensitive (limit of detection?=?3?×?10?10?mol?L?1 and limit of quantitation?=?1?×?10?9?mol?L?1). It was successfully applied for the determination of VRL in spiked human serum without the necessity for pretreatment and/or time-consuming extraction steps prior to the analysis. 相似文献
866.
Herring NP AbouZeid K Mohamed MB Pinsk J El-Shall MS 《Langmuir : the ACS journal of surfaces and colloids》2011,27(24):15146-15154
This work reports the development of a fast and simple "one-pot" route for the synthesis of hybrid Au-ZnO hexagonal nanopyramids by sequential homogeneous-heterogeneous nucleation steps involving both Au and Zn ions using microwave irradiation (MWI). The rapid decomposition of zinc acetate by MWI in the presence of a mixture of oleic acid (OAc) and oleylamine (OAm) results in the formation of hexagonal ZnO nanopyramids. In the presence of Au ions, the initially formed Au nanocrystals act as heterogeneous nuclei for the nucleation and growth of the ZnO nanopyramids. The Au nanoparticles promote the heterogeneous nucleation of ZnO and the formation of the hexagonal base of the ZnO nanopyramids. Using preformed Au nanoparticles instead of Au ions results in a narrow size distribution of uniform Au-ZnO nanopyramids, each consisting of a gold nanoparticle embedded in the center of the hexagonal base of the ZnO nanopyramid. We study the factors that control the nucleation and growth of these complex structures, and provide new insights into the stepwise homogeneous-heterogeneous mechanism and the conventional heterogeneous nucleation on preformed Au nanoparticles. The formation of the hetero nanostructures Au-ZnO nanopyramids is strongly dependent on the molar ratios of OAc to OAm. The presence of OAc with a considerable dipole moment results in strong electrostatic interaction with the polar surfaces of the growing ZnO nanocrystals thus resulting in slowing the growth rate of the polar planes and allowing the formation of well-developed facets. In the absence of Au nanoparticles, a high concentration of zinc acetate and longer MWI times are required for the production of the nanopyramids. The gold nanoparticles could provide the metallic contact points within the hybrid nanopyramids which could facilitate the bottom-up assembly of Au-ZnO devices. Furthermore, the Au-ZnO nanopyramids could have improved performance in solar energy conversion and photocatalysis. 相似文献
867.
The complexes formed on the reaction of various metal ions viz., Cu(II) and Cu(I) with phenol derivatives viz. catechol, chlorogenic acid (CGA), hydroquinone and n-propyl gallate (nPG) were established by UV-visible spectroscopy. The metal/ligand complexing ratio and complexation constants have been determined. Further, we showed that nanoparticles of Cu can be prepared from metal-phenol complexes in the presence of a protein (gelatin) by γ-irradiation showing that the reduction is metal ion centered. Formation of Ag nanoparticles was also observed on photo-irradiation with xenon lamp in the presence of dihydroxy benzene. The Ag and Cu nanoparticles were characterized by transmission electron microscopy (TEM) and UV-visible absorption spectroscopy. TEM technique showed the presence of Cu and Ag nanoparticles with average size of 20 and 30 nm, respectively. 相似文献
868.
Najbjerg H Afseth NK Young JF Bertram HC Pedersen ME Grimmer S Vogt G Kohler A 《The Analyst》2011,136(8):1649-1658
We investigated the applicability of FTIR-spectroscopy as a high throughput screening method for detection of biochemical changes in intact liver cells in bulk upon fatty acid exposure. HepG2 cells adapted to serum free (HepG2-SF) growth were exposed to four different fatty acids, three octadecenoic acids, differing in cis/trans-configuration or double bond position (oleic acid, elaidic acid and vaccenic acid) as well as palmitic acid in three days. High throughput FTIR spectroscopic measurements on dried films of intact cells showed spectra with high signal-to-noise ratio and great reproducibility. When applying principal component analysis (PCA) a clear discrimination between fatty acid exposures was observed. Higher levels of triacylglycerides were accumulated in cells exposed to elaidic acid than when exposed to the other fatty acids; the least accumulation appeared to be in cells exposed to palmitic acid. An increased absorption at ~966 cm(-1) corresponding to trans-double bond was detected upon elaidic acid exposure but not upon vaccenic acid exposure. Instead, upon vaccenic acid exposure two new absorption bands were observed at 981 and 946 cm(-1) due to the presence of double bond conjugation. Raman spectroscopy on single cells, with and without treatment by vaccenic acid, confirmed the presence of conjugation. By fatty acid composition analysis, the conjugation was further specified to be conjugated linoleic acid (CLA) isomers. Thus, instead of being preserved as a monounsaturated fatty acid, vaccenic acid was converted into CLA in HepG2 cells. The results demonstrate the applicability of high-throughput FTIR spectroscopy as an explorative method in in vitro systems from which biologically relevant hypotheses can be generated and further investigated. 相似文献
869.
Shukla Arpit Parmar Paritosh Kapoor Gitanjali Goswami Dweipayan Jha Chaitanya Kumar Patel Baldev Saraf Meenu 《Molecular diversity》2022,26(1):555-568
Molecular Diversity - Microbes possess a tremendous potential to interact with their surroundings and have continued to shape the future of all life forms existing on earth. Of all the groups of... 相似文献
870.
Khaled Ahmed Mansour Mona El-Neketi Mohamed-Farid Lahloub Ahmed Elbermawi 《Molecules (Basel, Switzerland)》2022,27(11)
Unprecedented nanoemulsion formulations (NE) of Jasminum humile and Jasminum grandiflorum essential oils (EO) were prepared, and examined for their cytotoxic and antiviral activities. NE characterization and stability examination tests were performed to ensure formula stability. The antiviral activity was determined against hepatitis A (HAV) and herpes simplex type-1 (HSV-1) viruses using MTT assay, while the cytotoxic potential was determined against liver (HepG-2), breast (MCF-7), leukemia (THP-1) cancer cell lines and normal Vero cells. Statistical significance was determined in comparison with doxorubicin as cytotoxic and acyclovir as antiviral standard drugs. GC-MS analysis indicated twenty four compounds in the EO of J. humile and seventeen compounds in the EO of J. grandiflorum. Biological investigations of pure EOs revealed weak cytotoxic and antiviral effects. Nevertheless, their NE formulations exhibited high biological value as cytotoxic and antiviral agents. NE formulations also showed feasible selectivity index for the viral-infected and cancer cells (especially HepG-2) than normal Vero cells. Both nanoemulsions showed lower IC50 than standard doxorubicin against HepG-2 (26.65 and 22.58 vs. 33.96 μg/mL) and MCF-7 (36.09 and 36.19 vs. 52.73 μg/mL), respectively. The study results showed the dramatic effect of nanoemulsion preparation on the biological activity of EOs and other liposoluble phytopharmaceuticals. 相似文献