Prediction of Solubility Parameters Based on the Explicit Expression of Statistical Thermodynamics

A robust and efficient procedure is presented for calculating the solubility parameter. An analytical equation for internal pressure is proposed. Through a simple relation reported by Verdier and Andersen (fluid phase equilibrium 231: 125–137, 2005), one can easily find the solubility parameter via our analytical equation for the internal pressure. Also, the radial distribution function (RDF) of a Lennard–Jones LJ (12, 6) fluid, proposed by Xu and Hu (fluid phase equilibrium 30: 221–228, 1986), has been employed to calculate the internal pressure of normal alkanes from methane to decane. Their solubility parameters were evaluated according to the calculated values of the internal pressure. A comparison between the experimental and the estimated values demonstrated a very good agreement between them.     

Microwave-Assisted Aminomethylation of Electron-Rich Compounds Under Solvent-Free Condition

Electron-rich aromatic compounds react with formaldehyde and a secondary amine under solvent-free condition, in the presence of acidic alumina in a commercial microwave oven or at room temperature to produce aminomethylated products in good to excellent yields.