Study on the Interaction of the CpG Alternating DNA with CdTe Quantum Dots

A novel sensitive method for detection of DNA methylation was developed with thioglycollic acid (TGA)-capped CdTe quantum dots (QDs) as fluorescence probes. Recognition of methylated DNA sites would be useful strategy due to the important roles of methylation in disease occurrence and developmental processes. DNA methylation occurs most often at cytosine-guanine sites (CpG dinucleotides) of gene promoters. The QDs significantly interacted with hybridized unmethylated and methylated DNA. The interaction of CpG rich methylated and unmethylated DNA hybrid with quantum dots as an optical probe has been investigated by fluorescence spectroscopy and electrophoresis assay. The fluorescence intensity of QDs was highly dependent to unmethylated and methylated DNA. Specific site of CpG islands of Adenomatous polyposis coli (APC), a well-studied tumor suppressor gene, was used as the detection target. Under optimum conditions, upon the addition of unmethylated dsDNA, the fluorescence intensity increased in linear range from 1.0?×?10^??10 to 1.0?×?10^??6M with detection limit of 6.2?×?10^??11 M and on the other hand, the intensity of QDs showed no changes with addition of methylated dsDNA. We also demonstrated that the unmethylated and methylated DNA and QDs complexes showed different mobility in electrophoresis assay. This easy and reliable method could distinguish between methylated and unmethylated DNA sequences.     

A neutron polarization analysis study of Ce2Fe17 in its paramagnetic phase

Spin-flip (paramagnetic) scattering and neutron depolarization studies were performed on Ce₂Fe₁₇ in its paramagnetic phase on the Dhruva neutron polarization analysis spectrometer. The absence of normalQ dependence of the scattered spin flip intensity shows that Ce₂Fe₁₇ is not a normal paramagnetic and there exist superparamagnetic clusters of sufficiently large dimensions (～100Å). The observed neutron depolarization gives an indication of the dynamics of these Ce₂Fe₁₇ superparamagnetic clusters.     

Analytical Holographic Superconductor with Backreaction Using AdS 3/CFT 2

The holographic model for a two-dimensional superconductor has been investigated by considering the three-dimensional gravity in the bulk. To find the critical temperature, we used the Sturm–Liouville variational method. Where as the same method is applied for calculating the condensation of the dual operators on the boundary. We included the back reactions on the metric by a combination of the perturbation method of the fields with respect to the small parameter and then applying the variational integrals on the resulting equations of the motion. The critical temperature has been successfully obtained on the backreaction effects, and we showed that it dropped with a rise in the backreaction of the fields, and it makes the condensation harder. We can use our analytical results to support the numerical data which was reported previously.     

Tachyon-polytropic inflation on the brane

We consider the tachyon-brane inflationary universe model in the context of a polytropic gas equation of state. In slow-roll approximation, we discuss general conditions of this model. For exponential potential, in high-energy limit the characteristics of the model are presented. By using the seven-year Wilkinson Microwave Anisotropy Probe (WMAP7) observational data, we constrain the cosmological parameters of the model.     

Enhancement of free space optical link in heavy rain attenuation using multiple beam concept

Free space optics (FSO) has attracted a lot of attention for a variety of applications in telecommunications area, and it is dream of every researcher and telecommunication society to make it a real alternative solution for the last mile problem, to replace fiber optics. FSO is much preferred because of its low maintenance cost and deployment time. FSO with single-beam system is vulnerable to atmospheric attenuation, so to overcome this, a multiple-beam FSO transceiver system has become prominent and is usually used. In this paper, average rain attenuation is evaluated from the collected rain intensity data which are collected for a period of seven months, and implemented in the study concerning results relating link distance, and received optical power of using multiple-beam FSO system in tropical rainy weather. Comparison is made in terms of received optical power, geometrical losses, atmospheric losses, and bit error rate (BER) on using different number of optical beams, based on simulation at data rate of 1 Gb/s. From the results it is clear that the quality of received power is improved by using up to four beams, along with link distance up to 1141.2 m as compared to one-beam, two-beam, and three-beam, with link distances 833.3 m, 991.0 m, 1075.4 m, respectively.     

Fingerprint image enhancement using data driven Directional Filter Bank

A new method based upon data driven tool, principal component analysis (PCA), for fingerprint enhancement is proposed in this paper. PCA is a very useful statistical technique that has found application in many different fields like image compression, face recognition and is commonly used for finding patterns in data of high dimension. In the proposed method, the input image is first decomposed into directional images using decimation free Directional Filter Bank (DDFB). Then these directional images are normalized. A data driven technique PCA is applied to these normalized directional fingerprint images, which gives the PCA filtered images. These are basically directional images. Then these directional images are reconstructed into one image which is the enhanced one. Simulation results are included illustrating the capability of the proposed method.     

Novel model of FM-noise conversion in a UMZI using RF external phase modulation of lasers: Theoretical and experimental results

In this paper, we propose and demonstrate a new and original model for theoretical calculation and experimental measurement of the noise power spectral density (NPSD) in phase-modulated optical links. The phase modulation is operated in the RF frequency range by an external phase modulator. The NPSD is derived for the first time in interferometric systems, by considering all effects such as the 1/f FM noise of the laser and white noise applied to light from a 1550 nm DFB laser, with phase modulation. The results show for the first time the influence of the phase modulation index, modulation frequency and interferometric delay in the phase-to-intensity noise conversion. The experimental and simulation results of conversion of FM-noise to intensity noise in an optical link by considering the external RF phase modulation are shown with good agreement.     

Emodin,A Naturally Occuring Anthraquinone: Its Isolation and Spectrophotometric Determination in Rumex Cyprius Plant

A new method for isolation and specrophotometric determination of emodin is presented. Emodin was isolated by thin layer chromatography (tlc) and column chromatography (cc) techniques, as an orange long crystalline substance. Emodin exhibits two absorption maxima, at 420 and 520 nm. Stability of the color and the effect of pH were studied. Beer's law is obeyed in the range 2–30 ppm.

The method is applied to the determination of emodin in roots, stems, and leaves of Rumex cyprius plant.     

Shedding light on the structure of a photoinduced transient excimer by time-resolved diffraction

Time-resolved single-crystal diffraction performed with synchrotron radiation shows that the 53(1) micros phosphorescent state, generated in the crystalline phase of trimeric {[3,5-(CF3)(2)Pyrazolate]Cu}(3) molecules by exposure to 355 nm of light at 17 K, is due to the formation of an excimer rather than the shortening of the intramolecular Cu...Cu distances within the trimeric units, or the formation of a continuous chain of interacting molecules. One of the intermolecular Cu...Cu distances contracts by 0.56 Angstroms from 4.018(1) to 3.46(1) Angstroms;, whereas the interplanar spacing of the trimers is reduced by 0.65 Angstroms; from 3.952(1) to 3.33(1) Angstroms. Density-functional theory calculations support the formation of a Cu...Cu bond through the intermetallic transfer of a Cu 3d electron to a molecular orbital with a large 4p contribution on the reacting Cu atoms.     

B12N12纳米笼：潜在的二氧化氮检测传感器

利用密度泛函理论通过计算吸附能量、HOMO/LUMO能隙变化、电荷转移、结构扭曲等研究二氧化氮分子在B12N12纳米笼的吸附．此外,通过计算B₁₂N₁₂的电子结合能、Gibbs自由能、态密度和分子表面的静电势研究其稳定性和其它特性．B₁₂N₁₂纳米笼吸附二氧化氮显示三种构型．B₁₂N₁₂团簇的HOMO/LUMO能隙变化对二氧化氮分子的存在非常敏感,从自由团簇的6.84 eV降为NO₂/团簇稳定团簇的3.23 eV．团簇的导电性被极大地提高,表明B₁₂N₁₂纳米簇可能是潜在的二氧化氮气体分子检测传感器.