全文获取类型
收费全文 | 1406篇 |
免费 | 30篇 |
国内免费 | 7篇 |
专业分类
化学 | 1018篇 |
晶体学 | 7篇 |
力学 | 10篇 |
数学 | 58篇 |
物理学 | 350篇 |
出版年
2022年 | 9篇 |
2021年 | 15篇 |
2020年 | 10篇 |
2019年 | 16篇 |
2018年 | 12篇 |
2017年 | 13篇 |
2016年 | 15篇 |
2015年 | 21篇 |
2014年 | 28篇 |
2013年 | 68篇 |
2012年 | 67篇 |
2011年 | 88篇 |
2010年 | 45篇 |
2009年 | 56篇 |
2008年 | 71篇 |
2007年 | 93篇 |
2006年 | 62篇 |
2005年 | 72篇 |
2004年 | 65篇 |
2003年 | 60篇 |
2002年 | 66篇 |
2001年 | 36篇 |
2000年 | 33篇 |
1999年 | 21篇 |
1998年 | 18篇 |
1997年 | 16篇 |
1996年 | 12篇 |
1995年 | 17篇 |
1994年 | 20篇 |
1993年 | 12篇 |
1992年 | 19篇 |
1991年 | 17篇 |
1990年 | 20篇 |
1989年 | 16篇 |
1988年 | 20篇 |
1987年 | 11篇 |
1986年 | 12篇 |
1985年 | 25篇 |
1984年 | 20篇 |
1983年 | 8篇 |
1982年 | 11篇 |
1981年 | 17篇 |
1980年 | 12篇 |
1979年 | 18篇 |
1978年 | 11篇 |
1977年 | 7篇 |
1976年 | 9篇 |
1975年 | 9篇 |
1973年 | 10篇 |
1967年 | 8篇 |
排序方式: 共有1443条查询结果,搜索用时 15 毫秒
11.
Photoinduced electron transfer (PET) fluoroionophores (1b, 2b) that consist of diazacrown and two 9-anthryl pendants show fluorescent enhancement with various guest salts. The diaza-12-crown-4 derivative (2b) exhibited Zn(2+) selectivity and in the presence of this cation the host fluorescence intensity was increased by a factor of 182. The guest cation-induced fluorescence enhancement of 2b was larger than the diaza-18-crown-6 derivative (1b). 相似文献
12.
13.
14.
The use of polyamines as electroosmotic modifiers has been shown to be effective in enhancing resolution of protein glycoforms in capillary zone electrophoresis (CZE) using a bare capillary tube. In this study, effectiveness was evaluated by using a polyacrylamide-coated capillary tube instead of a bare capillary tube. Electropherograms obtained in the presence of polyamines were inferior to those obtained in their absence with respect to resolution. Electrophoretic mobility of the proteins decreased and their peaks were broadened by polyamines bound to them. This unfavorable effect was dependent on both the species of polyamines and the pH values of the electrolyte buffer. The reduction of resolution caused by polyamines was in the following order: spermidine (SPD) approximately spermidine-tri-hydrochloride (SPD-HCI) > putrescine (PUT) > hexamethonium chloride (HMC). The observed effect can be ascribed to the formation of complexes between the proteins and the polyamines. In addition, for the bare capillary tube the complexes showed interaction with the inner surface, resulting in local suppression of electroosmosis and poor resolution. The high resolution obtained in the coated capillary tube was reduced in the presence of the polyamines. Thus, the use of the polyamines has a negative effect on the analysis of protein microheterogeneity as a result of protein-polyamine interaction. 相似文献
15.
16.
17.
18.
19.
Y Nomoto H Takai T Hirata M Teranishi T Ohno K Kubo 《Chemical & pharmaceutical bulletin》1991,39(1):86-90
A series of 1-(6,7-dimethoxy-4-quinazolinyl)piperidines carrying various 5-membered heterocycles at the 4-position was synthesized and examined for cardiotonic activity in anesthesized dogs. The (4-oxo-2-thioxo-3-imidazolindinyl)amino derivatives showed the most potent inotropic activity. Marked loss of activity was observed in the 2,4-dihydro-3-thioxo-3H-1,2,4-triazolyl, the 2,4-dihydro-3-oxo-3H-pyrazolyl and the (2,3-dihydro-2-thioxo-3H-1,3,4-thiadiazol-5-yl)amino derivatives. The synthesis and structure-activity relationships are discussed. 相似文献
20.
Liposomes prepared from synthetic amphiphiles. I. Their technetium labeling and stability 总被引:1,自引:0,他引:1
In order to apply liposomes prepared from synthetic amphiphiles containing amino acid residues to radiopharmaceuticals, their labeling with 99Tc or 99mTc and stability in saline or in serum were investigated. These liposomes were highly labeled by embedding stearylamine-diethylenetriamine pentaacetic acid as a ligand of technetium. The labeling was more efficient at pH 7.0 than at pH 4.0 or 8.5. Among these technetium-labeled liposomes tested, liposomes containing the alanine residue were stable in saline or in 50% serum at 37 degrees C for at least 24 h, in contrast to liposomes (phosphatidylcholine: cholesterol = 1:1 molar ratio) whose stability had been enhanced by adding cholesterol. 相似文献